| Organism name | Populus angustifolia | 
|---|---|
| Genus | Populus | 
| Family | Salicaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Populus angustifolia | 
|---|---|
| Linked NCBI taxonomy ID | 351344 | 
| Linked level | species | 
| Family in NCBI taxonomy | Salicaceae | 
|---|---|
| ID | 3688 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00007937   | 2',4',6'-Trihydroxy-4-methoxydihydrochalcone | No. 90 | No. 13 |   | ||||
| C00007929   | 2',6'-Dihydroxy-4'-methoxydihydrochalcone | CHEMBL486009 | No. 90 | No. 13 |   | |||
| C00007928   | 2',4',6'-Trihydroxydihydrochalcone / 3-Phenyl-1-(2,4,6-trihydroxyphenyl)-1-propanone | CHEMBL503375 | 8 / 5 / 4 | No. 90 | No. 13 |   | ||
| C00007233   | Isosalipurpol / Chalconaringenin / Naringenin chalcone / trans-2',4,4',6'-Tetrahydroxychalcone / (2E)- 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-Propen-1-one | CHEMBL338066 | 12 / 20 / 21 | No. 92 | No. 13 |   | ||
| C00006933   | 2',4',6'-Trihydroxychalcone | CHEMBL129371 | 2 / 0 / 3 | No. 92 | No. 13 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q9UNA4 | DNA polymerase iota | Enzyme | C00007233 C00007928 | 0 / 0 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00007233 C00007928 | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00006933 C00007233 | 0 / 3 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00006933 C00007233 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00007233 C00007928 | 4 / 3 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00007928 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00007233 | 0 / 1 | 
| P04062 | Glucosylceramidase | Enzyme | C00007233 | 6 / 4 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00007233 | 7 / 3 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00007233 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00007928 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00007233 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00007233 | 1 / 2 | 
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00007233 | 0 / 0 | 
| Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00007928 | 0 / 0 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00007928 | 1 / 1 | 
| Q9HCT0 | Fibroblast growth factor 22 | Unclassified protein | C00007928 | 0 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #608013 | Gaucher disease, perinatal lethal | P04062 | 
| #230800 | Gaucher disease, type i | P04062 | 
| #230900 | Gaucher disease, type ii | P04062 | 
| #231000 | Gaucher disease, type iii | P04062 | 
| #231005 | Gaucher disease, type iiic | P04062 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #168600 | Parkinson disease, late-onset; pd | P04062 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00066 | Lewy body dementia (LBD) | P04062
                            (related) | 
| H00126 | Gaucher disease | P04062
                            (related) | 
| H00426 | Defects in the degradation of ganglioside | P04062
                            (related) | 
| H00810 | Progressive myoclonic epilepsy (PME) | P04062
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00017 | Esophageal cancer | P35354
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) |