Rhus javanica

• Index
• Plant Species
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Rhus javanica
Genus	Rhus
Family	Anacardiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Brucea javanica
Linked NCBI taxonomy ID	210348
Linked level	species

Family

Family in NCBI taxonomy	Simaroubaceae
ID	23808

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00032984	Fouquierone / (+)-Fouquierone	CHEMBL224814				No. 23	No. 51
C00033061	Isofouquierone peroxide / (+)-Isofouquierone peroxide					No. 23	No. 51
C00006941	Butein	CHEMBL128000	C040918	17 / 31 / 34	8 / 0	No. 92	No. 13
C00008026	Sulfuretin / Sulphuretin / 6,3',4'-Trihydroxyaurone	CHEMBL490355 CHEMBL513487	C054989	42 / 37 / 34		No. 450	No. 13
C00033379	Semialatic acid					No. 827

Human Protein / Gene in interactions

53 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11473	Vitamin D3 receptor	NR1I1	C00006941 C00008026	2 / 3
O00255	Menin	Unclassified protein	C00006941 C00008026	2 / 5
Q9UBT6	DNA polymerase kappa	Enzyme	C00006941 C00008026	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00006941 C00008026	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00006941 C00008026	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00006941 C00008026	1 / 2
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00006941	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00006941	0 / 0
Q9HBX9	Relaxin receptor 1	Relaxin receptor	C00008026	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00008026	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00006941	1 / 8
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00008026	0 / 0
P47901	Vasopressin V1b receptor	Vasopressin and oxytocin receptor	C00008026	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00008026	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00008026	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00008026	2 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00008026	4 / 2
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00008026	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00008026	7 / 3
Q9Y253	DNA polymerase eta	Enzyme	C00008026	1 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00008026	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00008026	3 / 1
P11308	Transcriptional regulator ERG	Unclassified protein	C00008026	1 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00008026	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00008026	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00008026	1 / 1
P10828	Thyroid hormone receptor beta	NR1A2	C00008026	3 / 1
P35968	Vascular endothelial growth factor receptor 2	Vegfr	C00006941	1 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00006941	2 / 3
P10696	Alkaline phosphatase, placental-like	Enzyme	C00008026	0 / 1
P08253	72 kDa type IV collagenase	M10A	C00008026	1 / 3
O15118	Niemann-Pick C1 protein	Unclassified protein	C00008026	1 / 1
Q8WXD0	Relaxin receptor 2	Relaxin receptor	C00008026	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00008026	0 / 0
P11362	Fibroblast growth factor receptor 1	Fgfr	C00006941	4 / 5
Q9UNA4	DNA polymerase iota	Enzyme	C00008026	0 / 0
P04062	Glucosylceramidase	Enzyme	C00006941	6 / 4
P10636	Microtubule-associated protein tau	Unclassified protein	C00008026	4 / 3
P10721	Mast/stem cell growth factor receptor Kit	Pdgfr	C00006941	4 / 3
P21802	Fibroblast growth factor receptor 2	TK tyrosine-protein kinase TLK subfamily	C00006941	9 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00008026	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00008026	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00008026	0 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00008026	0 / 0
O00487	26S proteasome non-ATPase regulatory subunit 14	Enzyme	C00008026	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00008026	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00008026	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00008026	1 / 4
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00006941	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00006941	0 / 3
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00008026	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00008026	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00008026	2 / 1

8 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00006941
1734	DIO2, 5DII, D2, DIOII, SelY, TXDI2	deiodinase, iodothyronine, type II (EC:1.97.1.10)	C00006941
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00006941
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00006941
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00006941
23411	SIRT1, SIR2L1	sirtuin 1	C00006941
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00006941
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00006941

Related Diseases

Diseases related to proteins in ChEMBL interactions