Penicillium brevicompactum
Species
KNApSAcK Entry
| Organism name | Penicillium brevicompactum |
|---|---|
| Genus | Penicillium |
| Family | Trichocomaceae |
| Kingdom | Fungi |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Penicillium brevicompactum |
|---|---|
| Linked NCBI taxonomy ID | 5074 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Aspergillaceae |
|---|---|
| ID | 1131492 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00042430
|
cyclo(D-Leu-L-Trp)
|
CHEMBL365348
CHEMBL471388 |
1 / 0 / 0 | No. 1509 |
|
|||
|
C00042429
|
cyclo(D-Ile-L-Trp)
|
CHEMBL472229
|
No. 1509 |
|
||||
|
C00011280
|
Brevianamide F
/ L-Prolyl-L-tryptophan anhydride |
CHEMBL563557
CHEMBL2031508 CHEMBL2031509 CHEMBL2031510 |
No. 1509 |
|
||||
|
C00042302
|
Brevicompanine C
/ (-)-Brevicompanine C |
CHEMBL472025
|
No. 3186 |
|
||||
|
C00027029
|
Brevicompanine B
/ (-)-Brevicompanine B |
No. 3186 |
|
|||||
|
C00027028
|
Brevicompanine A
/ (-)-Brevicompanine A |
No. 3186 |
|
|||||
|
C00011278
|
Brevianamide C
|
No. 4759 |
|
|||||
|
C00011279
|
Brevianamide D
|
No. 4759 |
|
|||||
|
C00018753
|
MPA
/ Melbex / NSC 129185 / Lilly 68618 / Mycophenolic acid |
CHEMBL866
|
D009173
|
111 / 72 / 58 | 29 / 11 | No. 5526 |
|
|
|
C00026932
|
Brevianamide E
|
No. 6081 |
|
|||||
|
C00027956
|
Brevioxime
/ (-)-Brevioxime |
No. 8874 |
|
Human Protein / Gene in interactions
112 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00018753 | 1 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00018753 | 4 / 1 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00018753 | 0 / 0 |
| P20839 | Inosine-5'-monophosphate dehydrogenase 1 | Oxidoreductase | C00018753 | 2 / 2 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00018753 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00018753 | 0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00018753 | 2 / 2 |
| P08246 | Neutrophil elastase | S1A | C00018753 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00018753 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00018753 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00018753 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00018753 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00018753 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00018753 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00018753 | 2 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00018753 | 11 / 10 |
| P37840 | Alpha-synuclein | Unclassified protein | C00018753 | 4 / 2 |
| P12268 | Inosine-5'-monophosphate dehydrogenase 2 | Oxidoreductase | C00018753 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00018753 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00018753 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00018753 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00018753 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00018753 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00018753 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00018753 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00018753 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00018753 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00018753 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00018753 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00018753 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00018753 | 0 / 1 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00018753 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00018753 | 1 / 8 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00018753 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00018753 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00018753 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00018753 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00018753 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00018753 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00018753 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00018753 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00018753 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00018753 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00018753 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00018753 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00018753 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00018753 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00018753 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00018753 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00018753 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00018753 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00018753 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00018753 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00018753 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00018753 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00018753 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00018753 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00018753 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00018753 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00018753 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00018753 | 1 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00018753 | 0 / 0 |
| P07384 | Calpain-1 catalytic subunit | C2 | C00042430 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00018753 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00018753 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00018753 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00018753 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00018753 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00018753 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00018753 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00018753 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00018753 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00018753 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00018753 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00018753 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00018753 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00018753 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00018753 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00018753 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00018753 | 2 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00018753 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00018753 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00018753 | 2 / 2 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00018753 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00018753 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00018753 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00018753 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00018753 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00018753 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00018753 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00018753 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00018753 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00018753 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00018753 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00018753 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00018753 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00018753 | 0 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00018753 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00018753 | 5 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00018753 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00018753 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00018753 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00018753 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00018753 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00018753 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00018753 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00018753 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00018753 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00018753 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00018753 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00018753 | 1 / 4 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00018753 | 1 / 1 |
29 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00018753
|
| 466 | ATF1, EWS-ATF1, FUS/ATF-1, TREB36 | activating transcription factor 1 |
C00018753
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00018753
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00018753
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00018753
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00018753
|
| 1385 | CREB1, CREB | cAMP responsive element binding protein 1 |
C00018753
|
| 1558 | CYP2C8, CPC8, CYPIIC8, MP-12/MP-20 | cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1) |
C00018753
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00018753
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00018753
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00018753
|
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00018753
|
| 3558 | IL2, IL-2, TCGF, lymphokine | interleukin 2 |
C00018753
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00018753
|
| 22914 | KLRK1, CD314, D12S2489E, KLR, NKG2-D, NKG2D | killer cell lectin-like receptor subfamily K, member 1 |
C00018753
|
| 4067 | LYN, JTK8, p53Lyn, p56Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) |
C00018753
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00018753
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00018753
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00018753
|
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00018753
|
| 4137 | MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU | microtubule-associated protein tau |
C00018753
|
| 9437 | NCR1, CD335, LY94, NK-p46, NKP46 | natural cytotoxicity triggering receptor 1 |
C00018753
|
| 9436 | NCR2, CD336, LY95, NK-p44, NKP44, dJ149M18.1 | natural cytotoxicity triggering receptor 2 |
C00018753
|
| 259197 | NCR3, 1C7, CD337, LY117, MALS, NKp30 | natural cytotoxicity triggering receptor 3 |
C00018753
|
| 5578 | PRKCA, AAG6, PKC-alpha, PKCA, PRKACA | protein kinase C, alpha (EC:2.7.11.13) |
C00018753
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00018753
|
| 6194 | RPS6, S6 | ribosomal protein S6 |
C00018753
|
| 6776 | STAT5A, MGF, STAT5 | signal transducer and activator of transcription 5A |
C00018753
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00018753
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (72)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #162800 | Cyclic neutropenia |
P08246
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
P37231 |
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613837 | Leber congenital amaurosis 11; lca11 |
P20839
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #180105 | Retinitis pigmentosa 10; rp10 |
P20839
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (58)
| KEGG | name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P20839
(related)
|
| H00837 | Leber congenital amaurosis (LCR) |
P20839
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
Diseases related to CTD interactions
11 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000740 | Anemia |
C00018753
|
| D005767 | Gastrointestinal Diseases |
C00018753
|
| D006086 | Graft vs Host Disease |
C00018753
|
| D006526 | Hepatitis C |
C00018753
|
| D007249 | Inflammation |
C00018753
|
| D007968 | Leukoencephalopathy, Progressive Multifocal |
C00018753
|
| D007970 | Leukopenia |
C00018753
|
| D055953 | Microscopic Polyangiitis |
C00018753
|
| D009336 | Necrosis |
C00018753
|
| D009421 | Nervous System Malformations |
C00018753
|
| D014890 | Wegener Granulomatosis |
C00018753
|