| Organism name | Wikstroemia viridiflora | 
|---|---|
| Genus | Wikstroemia | 
| Family | Thymelaeaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Wikstroemia | 
|---|---|
| Linked NCBI taxonomy ID | 142693 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Thymelaeaceae | 
|---|---|
| ID | 39987 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00007190   | (+)-Pinoresinol | CHEMBL267963 CHEMBL487611 CHEMBL460862 | C103298 | 7 / 5 / 6 | No. 38 | No. 21 |   | |
| C00000609   | (-)-Arctigenin | CHEMBL369142 CHEMBL435734 CHEMBL1966556 | C071942 | 13 / 7 / 6 | No. 223 | No. 21 |   | |
| C00000606   | (-)-Matairesinol | CHEMBL425148 | C068935 | 1 / 0 / 0 | No. 223 | No. 21 |   | |
| C00007203   | (+)-Wikstromol / (+)-Nortrachelogenin | CHEMBL453799 CHEMBL1483370 | 3 / 2 / 2 | No. 223 | No. 21 |   | ||
| C00002463   | Daphnoretin | CHEMBL508494 | C035316 | 14 / 11 / 10 | No. 1906 | No. 25 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00000609 C00007203 | 1 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000609 C00002463 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000609 C00002463 | 0 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 C00007203 | 0 / 0 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 | 5 / 3 | 
| P06746 | DNA polymerase beta | Enzyme | C00002463 | 0 / 0 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00007203 | 1 / 1 | 
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 | 0 / 0 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002463 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000609 | 0 / 1 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002463 | 1 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002463 | 0 / 0 | 
| P04278 | Sex hormone-binding globulin | Secreted protein | C00000606 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000609 | 2 / 0 | 
| O75496 | Geminin | Unclassified protein | C00002463 | 0 / 0 | 
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00000609 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000609 | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 | 0 / 3 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000609 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000609 | 0 / 0 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002463 | 3 / 3 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002463 | 2 / 2 | 
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00000609 | 1 / 1 | 
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000609 | 1 / 1 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000609 | 1 / 0 | 
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00000609 | 1 / 1 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002463 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002463 | 4 / 3 | 
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002463 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002463 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002463 | 1 / 1 | 
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 | 0 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| %606641 | Body mass index; bmi | P37231 | 
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 | Q02750 | 
| #609338 | Carotid intimal medial thickness 1 | P37231 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #137800 | Glioma susceptibility 1; glm1 | P37231 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | P37231 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #160900 | Myotonic dystrophy 1; dm1 | Q9NR56 | 
| #257220 | Niemann-pick disease, type c1; npc1 | O15118 | 
| #601665 | Obesity | P37231 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) | O15118
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00017 | Esophageal cancer | P35354
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00032 | Thyroid cancer | P37231
                            (related) | 
| H00409 | Type II diabetes mellitus | P37231
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P37231
                            (related) | 
| H00523 | Noonan syndrome and related disorders | Q02750
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) Q9NUW8 (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) |