| Organism name | Combretum apiculatum |
|---|---|
| Genus | Combretum |
| Family | Combretaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Combretum apiculatum |
|---|---|
| Linked NCBI taxonomy ID | 493957 |
| Linked level | species |
| Family in NCBI taxonomy | Combretaceae |
|---|---|
| ID | 3954 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00015209
|
2,3-Dimethoxy-4,6,7-trihydroxy-9,10-dihydrophenanthrene
|
No. 75 | No. 28 |
|
||||
|
C00033689
|
Callosin
|
No. 75 | No. 28 |
|
||||
|
C00015243
|
2,6-Dihydroxy-3,4,7-trimethoxy-9,10-dihydrophenanthrene
|
No. 75 | No. 28 |
|
||||
|
C00015683
|
7-Hydroxy-2,3,4,6-tetramethoxy-9,10-dihydrophenanthrene
|
CHEMBL79985
|
No. 75 | No. 28 |
|
|||
|
C00015256
|
2,7-Dihydroxy-3,4,6-trimethoxy-9,10-dihydrophenanthrene
|
No. 75 | No. 28 |
|
||||
|
C00015607
|
6,7-Dihydroxy-2,3,4-trimethoxy-9,10-dihydrophenanthrene
|
No. 75 | No. 28 |
|
||||
|
C00015545
|
4,7-Dihydroxy-2,6-dimethoxy-9,10-dihydrophenanthrene
|
No. 75 | No. 28 |
|
||||
|
C00015540
|
4,7-Dihydorxy-2,3,6-trimethoxy-9,10-dihydrophenanthrene
|
No. 75 | No. 28 |
|
||||
|
C00015425
|
3-Hydroxy-2,4,6,7-tetramethoxy-9,10-dihydrophenanthrene
|
No. 75 | No. 28 |
|
||||
|
C00015313
|
3,4'-Dihydroxy-4,5-dimethoxybibenzyl
|
No. 96 | No. 26 |
|
||||
|
C00015538
|
4,5-Dimethoxy-3,3',4'-trihydroxybibenzyl
|
No. 96 | No. 26 |
|
||||
|
C00015306
|
3,4'-Dihydroxy-3',4,5-trimethoxybibenzyl
|
No. 96 | No. 26 |
|
||||
|
C00015403
|
3,7-Dihydroxy-2,4,6-trimethoxyphenanthrene
|
No. 104 | No. 27 |
|
||||
|
C00015542
|
4,7-dihydroxy-2,3,6-trimethoxyphenanthrene
|
CHEMBL1346456
|
34 / 20 / 13 | No. 104 | No. 27 |
|
||
|
C00015210
|
4,6,7-Trihydroxy-2,3-dimethoxyphenanthrene
/ 2,3-Dimethoxy-4,6,7-trihydroxyphenanthrene |
No. 104 | No. 27 |
|
||||
|
C00015539
|
4,6-Dimethoxy,2,3,7-trihydroxyphenanthrene
|
No. 104 | No. 27 |
|
||||
|
C00015244
|
2,6-Dihydroxy-3,4,7-trimethoxyphenanthrene
|
No. 104 | No. 27 |
|
||||
|
C00015315
|
3,4'-Dihydroxy-5-methoxybibenzyl
|
CHEMBL448371
|
No. 242 | No. 26 |
|
|||
|
C00035241
|
9,10-Dihydrophenanthrene
|
No. 6139 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00015542 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00015542 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00015542 | 1 / 1 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00015542 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00015542 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00015542 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00015542 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00015542 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00015542 | 4 / 2 |
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00015542 | 0 / 0 |
| Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00015542 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00015542 | 1 / 2 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00015542 | 1 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00015542 | 2 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00015542 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00015542 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00015542 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00015542 | 0 / 0 |
| P98073 | Enteropeptidase | Enzyme | C00015542 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00015542 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00015542 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00015542 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00015542 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00015542 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00015542 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00015542 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00015542 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00015542 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00015542 | 1 / 0 |
| Q9UBT2 | SUMO-activating enzyme subunit 2 | Enzyme | C00015542 | 0 / 0 |
| Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00015542 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00015542 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00015542 | 2 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00015542 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #226200 | Enterokinase deficiency |
P98073
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00988 | Enterokinase deficiency |
P98073
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|