KCF-S cluster No. 104 (47 metabolites)

Corresponding Phytochemical cluster No. 27

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (47)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Liliopsida	79
rosids	18
Embryophyta	4
eudicotyledons	4

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Cumulative family count

class name	count
Orchidaceae	52
Dioscoreaceae	27
Combretaceae	17
Papaveraceae	4
Marchantiaceae	4
Betulaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Phenanthrenes	3

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metabolites link (3)

br08003 Category	KEGG ID	KNApSAcK ID
Phenanthrenes	C10246	C00000325
Phenanthrenes	C10244	C00002869
Phenanthrenes	C10265	C00002886

Metabolite list (47)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000325	Batatasin I / 6-Hydroxy-2,4,7-trimethoxyphenanthrene
C00002869	Agrostophyllin
C00002886	Isobatatasin I
C00015200	2,3,4,6,7-Pentamethoxyphenanthrene
C00015210	4,6,7-Trihydroxy-2,3-dimethoxyphenanthrene / 2,3-Dimethoxy-4,6,7-trihydroxyphenanthrene
C00015211	2,3-Dimethoxy-7-hydroxy-phenanthrere
C00015212	2,4,5,6-Tetrahydroxyphenanthrene
C00015242	Confusaridin / 2,6-Dihydroxy-3,4,7,8-tetramethoxy-9,10-dihydrophenanthrene
C00015244	2,6-Dihydroxy-3,4,7-trimethoxyphenanthrene
C00015257	2,7-Dihydroxy-3,4,6-trimethoxyphenanthrene
C00015258	Confusarin / 2,7-Dihydroxy-3,4,8-trimethoxy-9,10-dihydrophenanthrene
C00015259	2,7-Dihydroxy-3-methoxyphenanthrene
C00015260	2,7-Dihydroxy-4,6-dimethoxyphenanthrene	CHEMBL509668
C00015264	2,8-Dimethoxy-7-hydroxy-3,4,-methylenedioxyphenanthrene
C00015273	2-Hydroxy-3,6-dimethoxyphenanthrene
C00015302	O-Methylthebaol / O-Methyl-alpha-thebaol / 3,4,6-Trimethoxyphenanthrene
C00015318	3,4-Dimethoxy-2,6,7-trihydroxyphenanthrene
C00015402	alpha-Thebaol / 3,6-Dimethoxy-4-hydroxyphenanthrene
C00015403	3,7-Dihydroxy-2,4,6-trimethoxyphenanthrene
C00015404	3,7-Dihydroxy-2,4-dimethoxyphenanthrene	CHEMBL1083093
C00015423	3,7-Dimethoxy-5-hydroxyphenanthrene
C00015427	3-Hydroxy-2,5-dimethoxyphenanthrene
C00015539	4,6-Dimethoxy,2,3,7-trihydroxyphenanthrene
C00015542	4,7-dihydroxy-2,3,6-trimethoxyphenanthrene	CHEMBL1346456		34 / 20 / 13
C00015543	4,7-Dihydroxy-2,3-dimethoxyphenanthrene
C00015547	Ta IX / 4,8-Dihydroxy-2,3,7trimethoxyphenanthrene
C00015590	Ta IV / 5,7-Dimethoxy-6-hydroxy-1,2-methylenedioxyphenanthrene
C00015608	6,7-Dihydroxy-2,3,4-trimethoxyphenanthrene
C00015609	6,7-Dihydroxy-2,4-dimethoxyphenanthrene
C00015685	7-Hydroxy-2,3,4,6-tetramethoxyphenanthrene	CHEMBL421968
C00015690	8-Hydroxy-2,3,4,7-tetramethoxyphenanthrene
C00015897	Moscatin / Plicatol B	CHEMBL448260	C091085
C00015898	Nudol	CHEMBL253983
C00015900	Bulbophyllanthrin / 3,5-Dihydroxy-2,4-dimethoxyphenanthrene	CHEMBL253981
C00015902	Gymnopusin / 7,9-Dihydroxy-2,3,4-trimethoxyphenanthrene	CHEMBL2208383
C00015903	Cirrhopetalin / 7-Hydroxy-4-methoxy-2,3-methylenedioxyphenanthrene
C00024152	Fimbriol A	CHEMBL2208382
C00024153	Fimbriol B	CHEMBL254188
C00033691	Callosuminin
C00033729	Coeloginanthrin
C00033765	Denthyrsinin	CHEMBL469491
C00033847	Flavanthrinin	CHEMBL447210
C00034034	Lusianthrin
C00034086	Ochrolic acid
C00034157	Plicatol A	CHEMBL438339
C00040831	4-Methoxyphenanthrene-2,3,6,7-tetrol
C00040832	4-Methoxyphenanthrene-2,3,7-triol

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00015542	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00015542	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00015542	1 / 1
P14618	Pyruvate kinase PKM	Enzyme	C00015542	0 / 0
P06746	DNA polymerase beta	Enzyme	C00015542	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00015542	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00015542	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00015542	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00015542	4 / 2
Q00535	Cyclin-dependent kinase 5	Cdk5	C00015542	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00015542	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00015542	1 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00015542	1 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00015542	2 / 2
P39748	Flap endonuclease 1	Enzyme	C00015542	0 / 0
O75496	Geminin	Unclassified protein	C00015542	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00015542	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00015542	0 / 0
P98073	Enteropeptidase	Enzyme	C00015542	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00015542	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00015542	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00015542	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00015542	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00015542	4 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00015542	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00015542	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00015542	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00015542	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00015542	1 / 0
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00015542	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00015542	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00015542	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00015542	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00015542	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions