Species

KNApSAcK Entry

Organism name Drypetes molunduana Pax and Hoffm
Genus Drypetes
Family Putranjivaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Drypetes
Linked NCBI taxonomy ID 20145
Linked level genus

Family

Family in NCBI taxonomy Putranjivaceae
ID 233879

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00030459 External link 512 Hederagenin
CHEMBL486400
CHEMBL492472
CHEMBL1436053
C025763
7 / 11 / 11 No. 13 No. 51
C00019065 External link 512 Erythrodiol
/ 3beta-Erythrodiol
CHEMBL298604
CHEMBL60687
CHEMBL400074
C077953
4 / 0 / 1 No. 13 No. 51
C00000627 External link 512 (-)-Lirioresinol B
/ (-)-Syringaresinol
CHEMBL361362
CHEMBL402653
1 / 0 / 0 No. 38 No. 21
C00037073 External link 512 Drypemolundein B
/ (-)-Drypemolundein B
No. 101 No. 52
C00033565 External link 512 Acetyloleanolic acid
/ Oleanolic acid acetate
/ 3-O-Acetyloleanolic acid
/ (+)-Acetyloleanolic acid
/ (+)-Oleanolic acid acetate
/ (+)-3-O-Acetyloleanolic acid
/ 3beta-Acetoxyolean-12-en-28-oic acid
CHEMBL486822
CHEMBL494653
CHEMBL1315416
C052658
1 / 0 / 0 No. 177
C00037072 External link 512 Drypemolundein A
/ (-)-Drypemolundein A
No. 8259

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00019065 C00030459 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00030459 C00033565 0 / 0
P15559 NAD(P)H dehydrogenase [quinone] 1 Enzyme C00030459 0 / 0
P02545 Prelamin-A/C Unclassified protein C00030459 11 / 10
P08047 Transcription factor Sp1 Unclassified protein C00030459 0 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00019065 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00000627 0 / 0
P15121 Aldose reductase Enzyme C00019065 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00030459 0 / 1
P17706 Tyrosine-protein phosphatase non-receptor type 2 Tyr C00019065 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00030459 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (12)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00408 Type I diabetes mellitus P17706 (related)