Species

KNApSAcK Entry

Organism name Achillea holosericea
Genus Achillea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Achillea holosericea
Linked NCBI taxonomy ID 282740
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000642 External link 512 (+)-Yangambin
CHEMBL510536
CHEMBL454592
CHEMBL1412125
4 / 2 / 0 No. 38 No. 21
C00002595 External link 512 4'-Demethylpodophyllotoxin
CHEMBL28941
CHEMBL31929
CHEMBL290640
CHEMBL172476
CHEMBL172001
CHEMBL1514122
CHEMBL1723729
6 / 4 / 2 No. 427 No. 21

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00002595 4 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00002595 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00002595 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000642 2 / 0
O75496 Geminin Unclassified protein C00000642 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000642 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002595 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002595 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00000642 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00002595 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (2)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)