Species

KNApSAcK Entry

Organism name Scorzonera hispanica
Genus Scorzonera
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Scorzonera hispanica
Linked NCBI taxonomy ID 114289
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000659 External link 512 Medioresinol
/ (+)-Medioresinol
CHEMBL376507
CHEMBL513023
2 / 1 / 1 No. 38 No. 21
C00002631 External link 512 (+)-Lirioresinol B
/ (+)-Syringaresinol
CHEMBL361362
CHEMBL402653
C042192
1 / 0 / 0 No. 38 No. 21
C00007190 External link 512 (+)-Pinoresinol
CHEMBL267963
CHEMBL487611
CHEMBL460862
C103298
7 / 5 / 6 No. 38 No. 21
C00002727 External link 512 Coniferin
/ Coniferoside
CHEMBL459056
C016316
2 / 0 / 0 No. 678 No. 6

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000659 1 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00007190 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00007190 0 / 3
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00007190 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00002631 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002727 0 / 0
P39748 Flap endonuclease 1 Enzyme C00002727 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00007190 5 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00007190 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000659 0 / 1
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00007190 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00007190 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231

KEGG DISEASE (7)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)