| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00018986
|
Dalversinol A
/ 5,7,2',4'-Tetrahydroxy-8-prenyl-3'-(1,1-dimethyl-2-propenyl)isoflavanone |
CHEMBL463094
|
No. 19 | No. 14 |
|
|||
|
C00018987
|
(+)-Medicarpin
/ (+)-(6aS,11aS)-Medicarpin |
CHEMBL238845
CHEMBL413297 |
3 / 1 / 1 | No. 66 | No. 15 |
|
||
|
C00018988
|
Resveratrol trimethyl ether
/ 3,5,4'-Trimethoxy-trans-stilbene |
CHEMBL296411
CHEMBL311636 |
25 / 16 / 22 | No. 344 | No. 13 |
|
||
|
C00043202
|
4',6'-Dihydroxy-3',5'-dimethyl-2'-methoxychalcone
|
CHEMBL463095
|
No. 1043 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P17252 | Protein kinase C alpha type | Alpha | C00018988 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00018988 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00018988 | 1 / 0 |
| Q12778 | Forkhead box protein O1 | Unclassified protein | C00018988 | 1 / 1 |
| O75496 | Geminin | Unclassified protein | C00018987 | 0 / 0 |
| P01106 | Myc proto-oncogene protein | Unclassified protein | C00018988 | 1 / 13 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00018988 | 4 / 4 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00018988 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00018988 | 1 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00018987 | 0 / 0 |
| P00519 | Tyrosine-protein kinase ABL1 | Abl | C00018988 | 1 / 2 |
| P11274 | Breakpoint cluster region protein | Bcr | C00018988 | 1 / 2 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00018988 | 0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00018988 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00018988 | 1 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00018988 | 2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00018988 | 0 / 0 |
| P07437 | Tubulin beta chain | Structural | C00018988 | 0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00018988 | 1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00018988 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00018988 | 2 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00018987 | 1 / 1 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00018988 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00018988 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00018988 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00018988 | 0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00018988 | 0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00018988 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #113970 | Burkitt lymphoma; bl |
P01106
|
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #608232 | Leukemia, chronic myeloid; cml |
P00519
P11274 |
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #604229 | Peters anomaly |
Q16678
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #268220 | Rhabdomyosarcoma 2; rms2 |
Q12778
|
| KEGG | name | UniProt |
|---|---|---|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
P00519
(related)
P00519 (marker) P01106 (related) P01106 (marker) P11274 (related) P11274 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
P00519
(related)
P00519 (marker) P11274 (related) P11274 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
P01106
(related)
|
| H00008 | Burkitt lymphoma |
P01106
(related)
P01106 (marker) |
| H00010 | Multiple myeloma |
P01106
(related)
|
| H00013 | Small cell lung cancer |
P01106
(related)
|
| H00016 | Oral cancer |
P01106
(related)
|
| H00025 | Penile cancer |
P01106
(related)
|
| H00027 | Ovarian cancer |
P01106
(related)
|
| H00028 | Choriocarcinoma |
P01106
(related)
|
| H00031 | Breast cancer |
P01106
(related)
|
| H00036 | Osteosarcoma |
P01106
(related)
|
| H00041 | Kaposi's sarcoma |
P01106
(related)
|
| H00055 | Laryngeal cancer |
P01106
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00037 | Alveolar rhabdomyosarcoma |
Q12778
(related)
Q12778 (marker) |
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|