PCIDB

Cassia nomae

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	rosids
ID	71275

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00019420	Physcion / 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone	CHEMBL42624	C008905	18 / 20 / 14	1 / 0	No. 41	No. 62

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08246	Neutrophil elastase	S1A	C00019420	2 / 1
P11473	Vitamin D3 receptor	NR1I1	C00019420	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00019420	0 / 0
P08311	Cathepsin G	S1A	C00019420	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00019420	0 / 0
Q9H244	P2Y purinoceptor 12	Purine receptor	C00019420	1 / 1
P06280	Alpha-galactosidase A	Enzyme	C00019420	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00019420	2 / 2
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00019420	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00019420	4 / 3
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00019420	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00019420	0 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00019420	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00019420	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00019420	0 / 1
P03372	Estrogen receptor	NR3A1	C00019420	1 / 1
P09619	Platelet-derived growth factor receptor beta	Pdgfr	C00019420	5 / 1
P16234	Platelet-derived growth factor receptor alpha	Pdgfr	C00019420	2 / 1

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00019420

OMIM	preferred title	UniProt
#615007	Basal ganglia calcification, idiopathic, 4; ibgc4	P09619
#609821	Bleeding disorder, platelet-type, 8; bdplt8	Q9H244
#162800	Cyclic neutropenia	P08246
#119900	Digital clubbing, isolated congenital	P15428
#615363	Estrogen resistance; estrr	P03372
#301500	Fabry disease	P06280
#600274	Frontotemporal dementia; ftd	P10636
#606764	Gastrointestinal stromal tumor; gist	P16234
#607685	Hypereosinophilic syndrome, idiopathic; hes	P16234
#259100	Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1	P15428
#607785	Juvenile myelomonocytic leukemia; jmml	P09619
#601626	Leukemia, acute myeloid; aml	P09619
#607948	Mycobacterium tuberculosis, susceptibility to	P11473
#131440	Myeloproliferative disorder, chronic, with eosinophilia	P09619
#228550	Myofibromatosis, infantile, 1; imf1	P09619
#202700	Neutropenia, severe congenital, 1, autosomal dominant; scn1	P08246
#260540	Parkinson-dementia syndrome	P10636
#172700	Pick disease of brain	P10636
#601104	Supranuclear palsy, progressive, 1; psnp1	P10636
#277440	Vitamin d-dependent rickets, type 2a; vddr2a	P11473

KEGG	name	UniProt
H00026	Endometrial Cancer	P03372 (marker) Q92731 (marker)
H00093	Combined immunodeficiencies (CIDs)	P06239 (related)
H00125	Fabry disease	P06280 (related)
H00100	Neutropenic disorders	P08246 (related)
H00042	Glioma	P09619 (related) P16234 (related)
H00058	Amyotrophic lateral sclerosis (ALS)	P10636 (related)
H00077	Progressive supranuclear palsy (PSP)	P10636 (related)
H00078	Frontotemporal lobar degeneration (FTLD)	P10636 (related)
H00342	Tuberculosis	P11473 (related)
H00784	Localized autosomal recessive hypotrichosis	P11473 (related)
H01143	Vitamin D-dependent rickets	P11473 (related)
H00457	Primary hypertrophic osteoarthropathy (PHO)	P15428 (related)
H01246	Isolated congenital nail clubbing (ICNC)	P15428 (related)
H01235	Bleeding disorder platelet-type	Q9H244 (related)