Species

KNApSAcK Entry

Organism name Haplophyllum bucharicum
Genus Haplophyllum
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Haplophyllum bucharicum
Linked NCBI taxonomy ID 1006069
Linked level species

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000701 External link 512 Justicidin B
No. 285 No. 21
C00025441 External link 512 Pteleprenine
C111713
No. 781
C00026388 External link 512 4-Hydroxyquinolin-2(1H)-one
CHEMBL223449
5 / 7 / 3 No. 3673
C00002142 External link 512 Bucharaine
CHEMBL1338870
7 / 10 / 13 No. 6960 No. 7
C00002143 External link 512 Bucharidine
CHEMBL1891586
1 / 0 / 0 No. 8566 No. 7

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002142 C00026388 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002142 2 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00026388 0 / 0
O75496 Geminin Unclassified protein C00026388 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00026388 7 / 3
P83916 Chromobox protein homolog 1 Unclassified protein C00002143 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00002142 1 / 0
Q16637 Survival motor neuron protein Unclassified protein C00002142 4 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00026388 0 / 0
O00255 Menin Unclassified protein C00002142 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002142 1 / 2
P01215 Glycoprotein hormones alpha chain Unclassified protein C00002142 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#119900 Digital clubbing, isolated congenital P15428
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (16)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)