Species

KNApSAcK Entry

Organism name Parabaena sagittata Miers
Genus Parabaena
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Parabaena
Linked NCBI taxonomy ID 152350
Linked level genus

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025252 External link 512 Rotundine
/ l-Tetrahydropalmatine
/ (-)-Tetrahydropalmatine
/ (-)-Rotundine(Stephania)
CHEMBL187892
CHEMBL487182
CHEMBL2334889
8 / 5 / 2 No. 37 No. 4
C00025255 External link 512 (-)-Thaicanine
CHEMBL465823
No. 37 No. 4
C00025337 External link 512 O-Methylthaicanine
/ (-)-O-Methylthaicanine
No. 37 No. 4
C00025347 External link 512 Tembetarine
/ (+)-Tembetarine
C003383
No. 896

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P21728 D(1A) dopamine receptor Dopamine receptor C00025252 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00025252 2 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00025252 1 / 0
P13726 Tissue factor Membrane receptor C00025252 0 / 0
P03372 Estrogen receptor NR3A1 C00025252 1 / 1
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00025252 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00025252 0 / 1
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00025252 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#615363 Estrogen resistance; estrr P03372
#159900 Myoclonic dystonia P14416
#614674 Periodic fever, menstrual cycle-dependent P08908

KEGG DISEASE (2)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)