Species

KNApSAcK Entry

Organism name Anthyllis subsimplex
Genus Anthyllis
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Anthyllis
Linked NCBI taxonomy ID 118889
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005524 External link 512 Isorhamnetin 3-galactoside
CHEMBL234316
CHEMBL516621
1 / 1 / 0 No. 2 No. 15
C00001110 External link 512 Vitexin
/ Apigenin 8-C-glucoside
/ 8-D-Glucosyl-4',5,7-trihydroxyflavone
/ 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL487417
CHEMBL1332209
CHEMBL1357921
16 / 4 / 8 No. 22 No. 15
C00000750 External link 512 Phenylacetic acid
CHEMBL1044
C025136
3 / 1 / 1 3 / 0 No. 2481

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P15121 Aldose reductase Enzyme C00000750 C00001110 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001110 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001110 0 / 1
O75496 Geminin Unclassified protein C00001110 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001110 1 / 0
Q9Y253 DNA polymerase eta Enzyme C00001110 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001110 0 / 0
P27169 Serum paraoxonase/arylesterase 1 Enzyme C00000750 1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001110 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001110 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001110 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00001110 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001110 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00005524 1 / 0
P06239 Tyrosine-protein kinase Lck Src C00000750 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001110 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001110 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001110 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001110 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00000750
5445 PON2 paraoxonase 2 (EC:3.1.1.2 3.1.1.81) C00000750
5446 PON3 paraoxonase 3 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00000750

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#612633 Microvascular complications of diabetes, susceptibility to, 5; mvcd5 P27169
#614674 Periodic fever, menstrual cycle-dependent P08908
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (9)

KEGG name UniProt
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)