Species

KNApSAcK Entry

Organism name Hypericum paturum
Genus Hypericum
Family Hypericaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hypericum
Linked NCBI taxonomy ID 55962
Linked level genus

Family

Family in NCBI taxonomy Hypericaceae
ID 629714

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00030348 External link 512 Normangostin
/ gamma-Mangostin
CHEMBL260553
C102777
5 / 2 / 5 No. 14 No. 15
C00032117 External link 512 Paxanthone
No. 24 No. 15
C00032369 External link 512 Toxyloxanthone B
CHEMBL482997
No. 24 No. 15

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00030348 0 / 3
P49327 Fatty acid synthase Transferase C00030348 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00030348 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00030348 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00030348 2 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511

KEGG DISEASE (5)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)