PCIDB

KNApSAcK Metabolite C00030348

Metabolite

KNApSAcK Entry

id C00030348
Name Normangostin / gamma-Mangostin
CAS RN 31271-07-5
Standard InChI InChI=1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3
Standard InChI (Main Layer) InChI=1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 14

Link

ChEMBL

By standard InChI CHEMBL260553
By standard InChI Main Layer CHEMBL260553

KEGG

By LinkDB

CTD

By CAS RN C102777

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL260553 CHEMBL1008495 (1)
0 / 3
P49327 Fatty acid synthase Transferase CHEMBL260553 CHEMBL1260142 (1)
0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL260553 CHEMBL1008496 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL260553 CHEMBL1785171 (1)
0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 CHEMBL260553 CHEMBL937818 (1) CHEMBL937820 (1)
CHEMBL937821 (2) CHEMBL937825 (1)
2 / 2

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511

KEGG DISEASE (5)

KEGG disease name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)