Garcina xipshuanbannaensis
Metabolite list (15)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00033668
|
Bannaxanthone C
|
No. 14 | No. 15 |
|
||||
|
C00030348
|
Normangostin
/ gamma-Mangostin |
CHEMBL260553
|
C102777
|
5 / 2 / 5 | No. 14 | No. 15 |
|
|
|
C00033667
|
Bannaxanthone B
|
No. 14 | No. 15 |
|
||||
|
C00030359
|
Garcinone E
|
CHEMBL454580
|
25 / 20 / 15 | No. 14 | No. 15 |
|
||
|
C00033957
|
Isojacareubin
|
No. 24 | No. 15 |
|
||||
|
C00033671
|
Bannaxanthone F
|
No. 44 |
|
|||||
|
C00033672
|
Bannaxanthone G
|
No. 44 |
|
|||||
|
C00033670
|
Bannaxanthone E
|
No. 44 |
|
|||||
|
C00033669
|
Bannaxanthone D
|
No. 44 |
|
|||||
|
C00033666
|
Bannaxanthone A
|
No. 47 | No. 15 |
|
||||
|
C00030357
|
Garcinone C
|
No. 47 | No. 15 |
|
||||
|
C00033898
|
Guttiferone E
|
CHEMBL454261
CHEMBL502489 CHEMBL2087609 |
2 / 1 / 1 | No. 123 |
|
|||
|
C00003023
|
Xanthochymol
|
CHEMBL454261
CHEMBL502489 CHEMBL2087609 |
C414432
|
2 / 1 / 1 | No. 123 |
|
||
|
C00033629
|
Allanxanthone C
|
No. 3043 |
|
|||||
|
C00033673
|
Bannaxanthone H
|
No. 3043 |
|
Human Protein / Gene in interactions
30 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q09472 | Histone acetyltransferase p300 | Enzyme | C00003023 C00033898 | 1 / 1 |
| Q92831 | Histone acetyltransferase KAT2B | Enzyme | C00003023 C00033898 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00030348 C00030359 | 2 / 2 |
| P49327 | Fatty acid synthase | Transferase | C00030348 C00030359 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00030348 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00030348 | 0 / 3 |
| P06746 | DNA polymerase beta | Enzyme | C00030359 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00030359 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00030359 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00030359 | 1 / 2 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00030348 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00030359 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00030359 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00030359 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00030359 | 7 / 3 |
| Q99700 | Ataxin-2 | Unclassified protein | C00030359 | 1 / 1 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00030359 | 1 / 1 |
| P17861 | X-box-binding protein 1 | Unclassified protein | C00030359 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00030359 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00030359 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00030359 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00030359 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00030359 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00030359 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00030359 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00030359 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00030359 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00030359 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00030359 | 0 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00030359 | 0 / 3 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (21)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #612371 | Major affective disorder 7; mafd7 |
P17861
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #613684 | Rubinstein-taybi syndrome 2; rsts2 |
Q09472
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (19)
| KEGG | name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00504 | Rubinstein-Taybi syndrome |
Q09472
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|