Species

KNApSAcK Entry

Organism name Calophyllum membranaceum
Genus Calophyllum
Family Calophyllaceae / Clusiaceae / Clusiaceae-Guttiferae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Calophyllum membranaceum
Linked NCBI taxonomy ID 1009336
Linked level species

Family

Family in NCBI taxonomy Calophyllaceae
ID 703253

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (12)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036468 External link 512 2,7-Dihydroxy-1,8-dimethoxyxanthone
No. 3 No. 15
C00042030 External link 512 1,8-Dimethoxy-2-hydroxyxanthone
No. 3 No. 15
C00038230 External link 512 2-Methoxyxanthone
CHEMBL186609
7 / 7 / 5 No. 76 No. 15
C00042127 External link 512 3-Hydroxy-4-methoxyxanthone
CHEMBL185895
1 / 1 / 1 No. 76 No. 15
C00035014 External link 512 2-Hydroxyxanthone
CHEMBL185960
1 / 1 / 1 No. 76 No. 15
C00042103 External link 512 3,4-Dihydroxyxanthone
CHEMBL446323
C074257
2 / 0 / 3 No. 76 No. 15
C00042142 External link 512 4-Hydroxyxanthone
CHEMBL359978
1 / 1 / 1 No. 76 No. 15
C00031602 External link 512 Apetalic acid
No. 1053
C00042288 External link 512 Blancoic acid
No. 1053
C00042629 External link 512 Isocalolongic acid
No. 1053
C00042383 External link 512 Chapelieric acid
No. 1383
C00042331 External link 512 Calanolide E2
/ (+)-Calanolide E2
No. 6193

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00035014 C00038230 C00042127 C00042142 1 / 1
O75496 Geminin Unclassified protein C00038230 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00042103 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00038230 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00042103 0 / 3
P38398 Breast cancer type 1 susceptibility protein Enzyme C00038230 4 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00038230 0 / 0
Q99816 Tumor susceptibility gene 101 protein Unclassified protein C00038230 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00038230 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398

KEGG DISEASE (8)

KEGG name UniProt
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00548 Brunner syndrome P21397 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)