| Organism name | Fucus vesiculosus | 
|---|---|
| Genus | Fucus | 
| Family | Fucaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Fucus vesiculosus | 
|---|---|
| Linked NCBI taxonomy ID | 49266 | 
| Linked level | species | 
| Family in NCBI taxonomy | Fucaceae | 
|---|---|
| ID | 3010 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Eukaryota | 
|---|---|
| ID | 2759 | 
| Plant class | |
|---|---|
| ID | 
| Species | Activity | 
|---|---|
| Fucus vesiculosus L. | Alterative | 
| Fucus vesiculosus L. | Antiaggregant | 
| Fucus vesiculosus L. | Antihypothyroid | 
| Fucus vesiculosus L. | Antiobesity | 
| Fucus vesiculosus L. | Antirheumatic | 
| Fucus vesiculosus L. | Antiseptic | 
| Fucus vesiculosus L. | Demulcent | 
| Fucus vesiculosus L. | Depurative | 
| Fucus vesiculosus L. | Emollient | 
| Fucus vesiculosus L. | Hemagglutinant | 
| Fucus vesiculosus L. | Hypoglycemic | 
| Fucus vesiculosus L. | Immunomodulator | 
| Fucus vesiculosus L. | Laxative | 
| Fucus vesiculosus L. | Metal-Chelator | 
| Fucus vesiculosus L. | Tonic | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00000931   | Zeaxanthin / all-trans-Zeaxanthin | CHEMBL1357855 CHEMBL2359248 | C005881 | 4 / 2 / 3 | 1 / 0 | No. 26 | No. 59 |   | 
| C00003653   | Fucosterol / (24R)24-Ethylcholesta-5,24(28)-dien-3beta-ol | CHEMBL519971 CHEMBL1836654 | C015896 | No. 53 | No. 11 |   | ||
| C00003773   | Fucoxanthin | CHEMBL1575074 | C025164 | 12 / 17 / 46 | 6 / 3 | No. 114 | No. 59 |   | 
| C00040472   | Tetrafucol A | No. 270 |   | |||||
| C00040473   | Tetrafucol B | No. 270 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000931 C00003773 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00000931 C00003773 | 0 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00000931 C00003773 | 2 / 3 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000931 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003773 | 2 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00003773 | 1 / 1 | 
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00003773 | 0 / 1 | 
| P06280 | Alpha-galactosidase A | Enzyme | C00003773 | 1 / 1 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003773 | 4 / 3 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003773 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00003773 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00003773 | 0 / 0 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00003773 | 7 / 37 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) | C00000931 | 
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 | C00003773 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00003773 | 
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) | C00003773 | 
| 2697 | GJA1, AVSD3, CMDR, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD | gap junction protein, alpha 1, 43kDa | C00003773 | 
| 2705 | GJB1, CMTX, CMTX1, CX32 | gap junction protein, beta 1, 32kDa | C00003773 | 
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) | C00003773 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #133239 | Esophageal cancer | P04637 | 
| #301500 | Fabry disease | P06280 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #211980 | Lung cancer | P04637 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00033 | Adrenal carcinoma | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H00125 | Fabry disease | P06280
                            (related) | 
| H00079 | Asthma | P07550
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) |