Celastrus orbiculatus

• Index
• Plant Species
• Metabolite list (16)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Celastrus orbiculatus
Genus	Celastrus
Family	Celastraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Celastrus orbiculatus
Linked NCBI taxonomy ID	85181
Linked level	species

Family

Family in NCBI taxonomy	Celastraceae
ID	4305

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (16)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005432	Quercetin 3,7-dirhamnoside / Quercetin 3,7-di-O-alpha-L-rhamnopyranoside					No. 1	No. 15
C00005428	Quercetin 3-glucoside-7-rhamnoside / Quercetin 3-O-glucoside-7-O-rhamnoside / Quercetin 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside	CHEMBL592361 CHEMBL1774171				No. 1	No. 15
C00000956	(-)-Epicatechin	CHEMBL80941 CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912		85 / 58 / 54		No. 52	No. 14
C00048243	(3'Z,5'Z)-Celaxanthin					No. 131	No. 59
C00048244	(3'Z,5'Z)-Torulene					No. 131	No. 59
C00035955	6alpha-Acetoxy-9beta-benzoyloxy-1beta-cinnamoyloxy-8beta-(2-methylbutanoyloxy)-beta-dihydroagarofuran					No. 168
C00046249	Orbiculin F / (+)-Orbiculin F					No. 168
C00046248	Orbiculin E / (+)-Orbiculin E					No. 168
C00046246	Orbiculin A	CHEMBL500894				No. 168
C00046247	Orbiculin D / (+)-Orbiculin D					No. 173
C00029919	Celastrol	CHEMBL301982 CHEMBL1321090 CHEMBL1712082	C050414	46 / 43 / 67	100 / 0	No. 403	No. 51
C00013252	Epicatechin 5-O-beta-D-glucopyranoside-3-benzoate / (2R,3R)-3-(Benzoyloxy)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-5-yl beta-D-glucopyranoside	CHEMBL473673				No. 540
C00013188	[3R-[3alpha,5beta,5aalpha,6alpha(E),7alpha,9alpha,9aalpha]]-5,7-bis(Acetyloxy)octahydro-2,2,5a,9-tetramethyl-2H-3,9a-methano-1-benzoxepin-6-yl ester 3-phenyl-2-propenoic acid					No. 3318
C00013187	Isocelorbicol / (-)-Isocelorbicol / [3R-(3alpha,5beta,5aalpha,6alpha,7alpha,9alpha,9aalpha)]-Octahydro-2,2,5a,9-tetramethyl-2H-3,9a-methano-1-benzoxepin-5,6,7-triol					No. 4206
C00013190	Celorbicol / [3R-(3alpha,5beta,5aalpha,6alpha,9alpha,9aalpha,10R*)]-Octahydro-2,2,5a,9-tetramethyl-2H-3,9a-methano-1-benzoxepin-5,6,10-triol					No. 4206
C00038717	Celaphanol A / (+)-Celaphanol A	CHEMBL512226				No. 4786

Human Protein / Gene in interactions

113 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000956 C00029919	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000956 C00029919	1 / 2
O00255	Menin	Unclassified protein	C00000956 C00029919	2 / 5
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000956 C00029919	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000956 C00029919	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00000956 C00029919	4 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00000956 C00029919	4 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00000956 C00029919	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000956 C00029919	0 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000956 C00029919	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000956 C00029919	2 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000956 C00029919	3 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00000956 C00029919	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000956 C00029919	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000956 C00029919	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000956 C00029919	2 / 0
P39748	Flap endonuclease 1	Enzyme	C00000956 C00029919	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000956 C00029919	2 / 3
P07451	Carbonic anhydrase 3	Lyase	C00000956	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00000956	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000956	0 / 1
Q16543	Hsp90 co-chaperone Cdc37	Unclassified protein	C00029919	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00029919	4 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00000956	3 / 2
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000956	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000956	1 / 2
P02768	Serum albumin	Secreted protein	C00000956	0 / 0
P49327	Fatty acid synthase	Transferase	C00000956	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000956	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00000956	1 / 2
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000956	0 / 0
P52209	6-phosphogluconate dehydrogenase, decarboxylating	Enzyme	C00000956	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000956	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000956	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000956	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000956	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00029919	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000956	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000956	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00000956	1 / 2
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00029919	4 / 2
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00029919	0 / 0
P07998	Ribonuclease pancreatic	Enzyme	C00000956	0 / 0
P11413	Glucose-6-phosphate 1-dehydrogenase	Enzyme	C00029919	1 / 2
Q00613	Heat shock factor protein 1	Unclassified protein	C00029919	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00000956	0 / 0
O75496	Geminin	Unclassified protein	C00029919	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000956	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000956	0 / 0
P07711	Cathepsin L1	C1A	C00000956	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00029919	0 / 0
P51684	C-C chemokine receptor type 6	CC chemokine receptor	C00029919	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000956	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000956	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000956	3 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00029919	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000956	0 / 0
P00734	Prothrombin	S1A	C00000956	4 / 2
P04745	Alpha-amylase 1	Enzyme	C00000956	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00029919	2 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00000956	2 / 3
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00029919	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000956	1 / 1
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000956	0 / 1
P56817	Beta-secretase 1	A1A	C00000956	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000956	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00000956	0 / 1
P06746	DNA polymerase beta	Enzyme	C00000956	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000956	3 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000956	5 / 2
P00374	Dihydrofolate reductase	Oxidoreductase	C00000956	1 / 1
P35372	Mu-type opioid receptor	Opioid receptor	C00000956	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000956	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00029919	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000956	0 / 3
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000956	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00029919	2 / 0
Q99700	Ataxin-2	Unclassified protein	C00029919	1 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00000956	1 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00029919	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000956	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000956	5 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000956	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00029919	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00029919	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00029919	0 / 0
P29350	Tyrosine-protein phosphatase non-receptor type 6	Tyr	C00029919	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00000956	1 / 1
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00000956	0 / 7
Q9NR96	Toll-like receptor 9	Toll-like and Il-1 receptors	C00029919	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00029919	7 / 37
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000956	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000956	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000956	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00029919	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000956	1 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000956	3 / 0
Q05513	Protein kinase C zeta type	Iota	C00000956	0 / 0
Q04759	Protein kinase C theta type	Delta	C00000956	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00000956	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00000956	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000956	0 / 0
Q05655	Protein kinase C delta type	Delta	C00000956	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00000956	1 / 1
P05771	Protein kinase C beta type	Alpha	C00000956	0 / 0
P24723	Protein kinase C eta type	Eta	C00000956	1 / 0
P41743	Protein kinase C iota type	Iota	C00000956	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00000956	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00029919	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00029919	0 / 3
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000956	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00029919	2 / 1
Q06710	Paired box protein Pax-8	Unclassified protein	C00029919	1 / 2

100 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
10598	AHSA1, AHA1, C14orf3, p38	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	C00029919
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00029919
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00029919
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00029919
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00029919
84159	ARID5B, DESRT, MRF-2, MRF2	AT rich interactive domain 5B (MRF1-like)	C00029919
467	ATF3	activating transcription factor 3	C00029919
9531	BAG3, BAG-3, BIS, CAIR-1, MFM6	BCL2-associated athanogene 3	C00029919
581	BAX, BCL2L4	BCL2-associated X protein	C00029919
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00029919
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00029919
694	BTG1	B-cell translocation gene 1, anti-proliferative	C00029919
8209	C21orf33, ES1, GT335, HES1, KNPH, KNPI	chromosome 21 open reading frame 33	C00029919
27101	CACYBP, GIG5, RP1-102G20.6, S100A6BP, SIP	calcyclin binding protein	C00029919
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00029919
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00029919
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00029919
831	CAST, BS-17	calpastatin	C00029919
874	CBR3, SDR21C2, hCBR3	carbonyl reductase 3 (EC:1.1.1.184)	C00029919
8317	CDC7, CDC7L1, HsCDC7, Hsk1, huCDC7	cell division cycle 7 (EC:2.7.11.1)	C00029919
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00029919
26973	CHORDC1, CHP1	cysteine and histidine-rich domain (CHORD) containing 1	C00029919
10370	CITED2, ASD8, MRG-1, MRG1, P35SRJ, VSD2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	C00029919
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00029919
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00029919
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00029919
3301	DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2	DnaJ (Hsp40) homolog, subfamily A, member 1	C00029919
11080	DNAJB4, DNAJW, DjB4, HLJ1	DnaJ (Hsp40) homolog, subfamily B, member 4	C00029919
1948	EFNB2, EPLG5, HTKL, Htk-L, LERK5	ephrin-B2	C00029919
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00029919
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00029919
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00029919
11153	FICD, HIP13, HYPE, UNQ3041	FIC domain containing (EC:2.7.7.n1)	C00029919
2322	FLT3, CD135, FLK-2, FLK2, STK1	fms-related tyrosine kinase 3 (EC:2.7.10.1)	C00029919
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00029919
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00029919
54676	GTPBP2	GTP binding protein 2	C00029919
29923	HILPDA, C7orf68, HIG-2, HIG2	hypoxia inducible lipid droplet-associated	C00029919
3157	HMGCS1, HMGCS	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)	C00029919
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00029919
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00029919
3303	HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1	heat shock 70kDa protein 1A	C00029919
3304	HSPA1B, HSP70-1B, HSP70-2	heat shock 70kDa protein 1B	C00029919
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00029919
10808	HSPH1, HSP105, HSP105A, HSP105B, NY-CO-25	heat shock 105kDa/110kDa protein 1	C00029919
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00029919
3458	IFNG, IFG, IFI	interferon, gamma	C00029919
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00029919
3557	IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4	interleukin 1 receptor antagonist	C00029919
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00029919
182	JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1	jagged 1	C00029919
3781	KCNN2, KCa2.2, SK2, SKCA2, SKCa_2, hSK2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	C00029919
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00029919
23175	LPIN1, PAP1	lipin 1 (EC:3.1.3.4)	C00029919
26046	LTN1, C21orf10, C21orf98, RNF160, ZNF294	listerin E3 ubiquitin protein ligase 1	C00029919
9935	MAFB, KRML, MCTO	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	C00029919
4191	MDH2, M-MDH, MDH, MGC:3559, MOR1	malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)	C00029919
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00029919
4335	MNT, MAD6, MXD6, ROX, bHLHd3	MAX network transcriptional repressor	C00029919
29074	MRPL18, L18mt, MRP-L18	mitochondrial ribosomal protein L18	C00029919
2956	MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160	mutS homolog 6	C00029919
6307	MSMO1, DESP4, ERG25, SC4MOL	methylsterol monooxygenase 1 (EC:1.14.13.72)	C00029919
23077	MYCBP2, PAM	MYC binding protein 2, E3 ubiquitin protein ligase	C00029919
55892	MYNN, OSZF, ZBTB31, ZNF902	myoneurin	C00029919
4683	NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95	nibrin	C00029919
4824	NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A	NK3 homeobox 1	C00029919
9315	NREP, C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17	neuronal regeneration related protein	C00029919
4986	OPRK1, K-OR-1, KOR, KOR-1, OPRK	opioid receptor, kappa 1	C00029919
51526	OSER1, C20orf111, HSPC207, Osr1, Perit1, dJ1183I21.1	oxidative stress responsive serine-rich 1	C00029919
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00029919
5152	PDE9A, HSPDE9A2	phosphodiesterase 9A (EC:3.1.4.35)	C00029919
5293	PIK3CD, P110DELTA, PI3K, p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153)	C00029919
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00029919
10105	PPIF, CYP3, CyP-M, Cyp-D, CypD	peptidylprolyl isomerase F (EC:5.2.1.8)	C00029919
5813	PURA, PUR-ALPHA, PUR1, PURALPHA	purine-rich element binding protein A	C00029919
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00029919
6241	RRM2, R2, RR2, RR2M	ribonucleotide reductase M2 (EC:1.17.4.1)	C00029919
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00029919
27230	SERP1, RAMP4	stress-associated endoplasmic reticulum protein 1	C00029919
27244	SESN1, PA26, SEST1	sestrin 1	C00029919
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00029919
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00029919
79811	SLTM, Met	SAFB-like, transcription modulator	C00029919
6659	SOX4, EVI16	SRY (sex determining region Y)-box 4	C00029919
100380807			C00029919
10963	STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L	stress-induced-phosphoprotein 1	C00029919
51347	TAOK3, DPK, JIK, MAP3K18	TAO kinase 3 (EC:2.7.11.1)	C00029919
7113	TMPRSS2, PP9284, PRSS10	transmembrane protease, serine 2 (EC:3.4.21.-)	C00029919
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00029919
8797	TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1	tumor necrosis factor receptor superfamily, member 10a	C00029919
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00029919
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00029919
10628	TXNIP, EST01027, HHCPA78, THIF, VDUP1	thioredoxin interacting protein	C00029919
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00029919
7320	UBE2B, E2-17kDa, HHR6B, HR6B, RAD6B, UBC2	ubiquitin-conjugating enzyme E2B (EC:6.3.2.19)	C00029919
7358	UGDH, GDH, UDP-GlcDH, UDPGDH, UGD	UDP-glucose 6-dehydrogenase (EC:1.1.1.22)	C00029919
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00029919
79084	WDR77, MEP-50, MEP50, Nbla10071, RP11-552M11.3, p44, p44/Mep50	WD repeat domain 77	C00029919
23099	ZBTB43, ZBTB22B, ZNF-X, ZNF297B	zinc finger and BTB domain containing 43	C00029919
80149	ZC3H12A, MCPIP, MCPIP1, RP3-423B22.1, dJ423B22.1	zinc finger CCCH-type containing 12A	C00029919

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Diseases related to proteins in ChEMBL interactions