Pterocarpus macrocarpus

• Index
• Plant Species
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Pterocarpus macrocarpus
Genus	Pterocarpus
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Pterocarpus macrocarpus
Linked NCBI taxonomy ID	108278
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00000977	Liquiritigenin	CHEMBL252642 CHEMBL271939	C083152	5 / 4 / 4	1 / 1	No. 25	No. 14
C00006120	Macrocarposide					No. 261	No. 14
C00002902	Pterostilbene / 3,5-Dimethoxy-4'-hydroxystilbene	CHEMBL87712 CHEMBL83527	C107773	19 / 19 / 20	54 / 15	No. 344	No. 13
C00012782	(+)-Pterocarpol / Eudesm-4(14)-ene-2a,11-diol / [2R-(2alpha,4aalpha,6beta,8abeta)]-decahydro-6-hydroxy-alpha,alpha,4a-trimethyl-8-methylene-2-naphthalenemethanol					No. 524	No. 38

Human Protein / Gene in interactions

23 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00000977 C00002902	2 / 2
Q04206	Transcription factor p65	Transcription Factor	C00000977	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002902	1 / 1
P14780	Matrix metalloproteinase-9	M10A	C00000977	2 / 2
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00002902	1 / 0
P08183	Multidrug resistance protein 1	drug	C00002902	1 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002902	0 / 0
O75496	Geminin	Unclassified protein	C00002902	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002902	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002902	4 / 2
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002902	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002902	0 / 3
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000977	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002902	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002902	1 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00002902	4 / 3
P05412	Transcription factor AP-1	Transcription Factor	C00000977	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002902	0 / 0
O00255	Menin	Unclassified protein	C00002902	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002902	1 / 2
P00519	Tyrosine-protein kinase ABL1	Abl	C00002902	1 / 2
P11274	Breakpoint cluster region protein	Bcr	C00002902	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002902	1 / 1

55 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1831	TSC22D3, DIP, DSIPI, GILZ, TSC-22R, hDIP	TSC22 domain family, member 3	C00000977
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002902
23600	AMACR, AMACRD, CBAS4, RACE, RM	alpha-methylacyl-CoA racemase (EC:5.1.99.4)	C00002902
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00002902
578	BAK1, BAK, BAK-LIKE, BCL2L7, CDN1	BCL2-antagonist/killer 1	C00002902
581	BAX, BCL2L4	BCL2-associated X protein	C00002902
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002902
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00002902
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002902
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00002902
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002902
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002902
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002902
2921	CXCL3, CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3	chemokine (C-X-C motif) ligand 3	C00002902
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002902
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002902
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00002902
56616	DIABLO, DFNA64, SMAC	diablo, IAP-binding mitochondrial protein	C00002902
1950	EGF, HOMG4, URG	epidermal growth factor	C00002902
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00002902
2002	ELK1	ELK1, member of ETS oncogene family	C00002902
2523	FUT1, H, HH, HSC	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) (EC:2.4.1.69)	C00002902
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00002902
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00002902
4670	HNRNPM, CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1, hnRNP_M	heterogeneous nuclear ribonucleoprotein M	C00002902
3313	HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74	heat shock 70kDa protein 9 (mortalin)	C00002902
3458	IFNG, IFG, IFI	interferon, gamma	C00002902
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002902
3696	ITGB8	integrin, beta 8	C00002902
3717	JAK2, JTK10, THCYT3	Janus kinase 2 (EC:2.7.10.2)	C00002902
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00002902
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002902
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00002902
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002902
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002902
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002902
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00002902
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002902
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002902
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002902
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00002902
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00002902
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00002902
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00002902
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002902
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002902
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002902
6301	SARS, SERRS, SERS	seryl-tRNA synthetase (EC:6.1.1.11)	C00002902
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002902
6667	SP1	Sp1 transcription factor	C00002902
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00002902
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002902
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002902
9189	ZBED1, ALTE, DREF, TRAMP, hDREF	zinc finger, BED-type containing 1	C00002902
118738	ZNF488	zinc finger protein 488	C00002902

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions