Species

KNApSAcK Entry

Organism name Wyethia glabra
Genus Wyethia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Wyethia glabra
Linked NCBI taxonomy ID 230218
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008304 External link 512 Sternbin
C079930
No. 25 No. 14
C00000997 External link 512 6-Prenylnaringenin
CHEMBL1537093
14 / 16 / 16 No. 28 No. 14
C00006952 External link 512 2',4',6'-Trihydroxy-4-methoxychalcone
CHEMBL133588
No. 92 No. 13

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04062 Glucosylceramidase Enzyme C00000997 6 / 4
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00000997 1 / 4
Q92830 Histone acetyltransferase KAT2A Enzyme C00000997 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000997 2 / 0
O75496 Geminin Unclassified protein C00000997 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00000997 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000997 1 / 2
P28482 Mitogen-activated protein kinase 1 Erk C00000997 0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00000997 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000997 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000997 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000997 4 / 3
Q13951 Core-binding factor subunit beta Unclassified protein C00000997 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00000997 1 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#208900 Ataxia-telangiectasia; at Q13315
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (16)

KEGG name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)