Species

KNApSAcK Entry

Organism name Alpinia officinarum
Genus Alpinia
Family Zingiberaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Alpinia officinarum
Linked NCBI taxonomy ID 199623
Linked level species

Family

Family in NCBI taxonomy Zingiberaceae
ID 4642

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Natural Activity

List (71)

Species Activity
Alpinia officinarum Hance Adenosis
Alpinia officinarum Hance Ague
Alpinia officinarum Hance Allergy
Alpinia officinarum Hance Alzheimer's
Alpinia officinarum Hance Anemia
Alpinia officinarum Hance Anorexia
Alpinia officinarum Hance Antibacterial
Alpinia officinarum Hance Antidiuretic
Alpinia officinarum Hance Antiinflammatory
Alpinia officinarum Hance Antiperiodic
Alpinia officinarum Hance Antiprostaglandin
Alpinia officinarum Hance Antispasmodic
Alpinia officinarum Hance Antitumor
Alpinia officinarum Hance Antiulcer
Alpinia officinarum Hance Aperitif
Alpinia officinarum Hance Aphrodisiac
Alpinia officinarum Hance Arthrosis
Alpinia officinarum Hance Bacteria
Alpinia officinarum Hance Bronchosis
Alpinia officinarum Hance Cancer
Alpinia officinarum Hance Cancer, bladder
Alpinia officinarum Hance Cancer, colon
Alpinia officinarum Hance Cancer, penis
Alpinia officinarum Hance Cancer, skin
Alpinia officinarum Hance Carminative
Alpinia officinarum Hance Catarrh
Alpinia officinarum Hance Cholecystosis
Alpinia officinarum Hance Cholera
Alpinia officinarum Hance Cold
Alpinia officinarum Hance Cramp
Alpinia officinarum Hance Dermatosis
Alpinia officinarum Hance Diarrhea
Alpinia officinarum Hance Dysmenorrhea
Alpinia officinarum Hance Dyspepsia
Alpinia officinarum Hance Emmenagogue
Alpinia officinarum Hance Enterosis
Alpinia officinarum Hance Epigastrosis
Alpinia officinarum Hance Fever
Alpinia officinarum Hance Flu
Alpinia officinarum Hance Freckle
Alpinia officinarum Hance Fungus
Alpinia officinarum Hance Gas
Alpinia officinarum Hance Gastrosis
Alpinia officinarum Hance Gingivosis
Alpinia officinarum Hance Halitosis
Alpinia officinarum Hance Hepatosis
Alpinia officinarum Hance Hypochondria
Alpinia officinarum Hance Infection
Alpinia officinarum Hance Inflammation
Alpinia officinarum Hance Malaria
Alpinia officinarum Hance Nervine
Alpinia officinarum Hance Pain
Alpinia officinarum Hance Pharyngosis
Alpinia officinarum Hance Polyuria
Alpinia officinarum Hance Pulmonosis
Alpinia officinarum Hance Rheumatism
Alpinia officinarum Hance Roemheld Syndrome
Alpinia officinarum Hance Seasickness
Alpinia officinarum Hance Sialagogue
Alpinia officinarum Hance Sore Throat
Alpinia officinarum Hance Stimulant
Alpinia officinarum Hance Stomachache
Alpinia officinarum Hance Stomachic
Alpinia officinarum Hance Stomatosis
Alpinia officinarum Hance Stone
Alpinia officinarum Hance Swelling
Alpinia officinarum Hance Syncope
Alpinia officinarum Hance Tonic
Alpinia officinarum Hance Toothache
Alpinia officinarum Hance Vertigo
Alpinia officinarum Hance vomiting

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001060 External link 512 Kaempferide
CHEMBL40919
6 / 7 / 4 No. 3 No. 15
C00004533 External link 512 Galangin
/ Norizalpinin
/ 3,5,7-Trihydroxyflavone
/ 3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one
CHEMBL309490
C037032
35 / 34 / 29 15 / 4 No. 76 No. 15
C00045488 External link 512 (3R,5R)-1-(4-Hydroxyphenyl)-7-phenyl-3,5-heptanediol
CHEMBL489757
CHEMBL539913
CHEMBL549729
No. 3495
C00029326 External link 512 (5S)-5-Methoxy-1,7-diphenyl-3-heptanone
CHEMBL240485
2 / 1 / 1 No. 4937
C00029365 External link 512 1,7-Diphenyl-4E-hepten-3-one
CHEMBL240484
No. 4937
C00030512 External link 512 Indomethacin
CHEMBL6
D007213
164 / 106 / 80 327 / 271 No. 6565

Human Protein / Gene in interactions

183 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001060 C00004533 C00030512 0 / 0
P08183 Multidrug resistance protein 1 drug C00001060 C00004533 C00030512 1 / 0
P03372 Estrogen receptor NR3A1 C00029326 C00030512 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00004533 C00030512 0 / 1
P10275 Androgen receptor NR3C4 C00004533 C00030512 3 / 4
P10636 Microtubule-associated protein tau Unclassified protein C00004533 C00030512 4 / 3
Q9UNA4 DNA polymerase iota Enzyme C00004533 C00030512 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00004533 C00030512 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00004533 C00030512 1 / 1
Q02880 DNA topoisomerase 2-beta Isomerase C00001060 C00004533 0 / 0
P22303 Acetylcholinesterase Hydrolase C00004533 C00030512 1 / 0
O00255 Menin Unclassified protein C00004533 C00030512 2 / 5
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001060 C00030512 2 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00004533 C00030512 1 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001060 C00004533 4 / 4
P33765 Adenosine receptor A3 Adenosine receptor C00004533 C00030512 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00004533 C00030512 0 / 1
Q92731 Estrogen receptor beta NR3A2 C00029326 C00030512 0 / 1
P29274 Adenosine receptor A2a Adenosine receptor C00004533 C00030512 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00004533 C00030512 0 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00004533 C00030512 1 / 2
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001060 C00004533 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00030512 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00030512 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00030512 2 / 2
P02545 Prelamin-A/C Unclassified protein C00030512 11 / 10
P43119 Prostacyclin receptor Prostanoid receptor C00030512 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00004533 1 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00030512 3 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00030512 0 / 0
Q9UP65 Cytosolic phospholipase A2 gamma Enzyme C00030512 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00030512 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00030512 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00030512 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00030512 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00030512 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00030512 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00030512 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00030512 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00030512 0 / 0
P02768 Serum albumin Secreted protein C00030512 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00030512 0 / 0
P40925 Malate dehydrogenase, cytoplasmic Enzyme C00030512 0 / 0
P17252 Protein kinase C alpha type Alpha C00030512 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00030512 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00030512 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00030512 0 / 0
P29466 Caspase-1 C14 C00030512 0 / 0
Q9Y5Y4 Prostaglandin D2 receptor 2 Prostanoid receptor C00030512 0 / 0
P16662 UDP-glucuronosyltransferase 2B7 Enzyme C00030512 0 / 0
O14684 Prostaglandin E synthase Enzyme C00030512 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00030512 1 / 8
P11388 DNA topoisomerase 2-alpha Isomerase C00004533 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00030512 2 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00030512 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00030512 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00030512 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00030512 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00030512 0 / 0
P04062 Glucosylceramidase Enzyme C00030512 6 / 4
P34972 Cannabinoid receptor 2 Cannabinoid receptor C00030512 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00030512 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00030512 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00030512 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00030512 1 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00004533 1 / 1
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00030512 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00030512 0 / 0
P42330 Aldo-keto reductase family 1 member C3 Enzyme C00030512 0 / 0
Q9BPW9 Dehydrogenase/reductase SDR family member 9 Enzyme C00030512 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00004533 2 / 0
O75496 Geminin Unclassified protein C00004533 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00030512 0 / 0
Q8TCC7 Solute carrier family 22 member 8 Antiporter C00030512 0 / 0
O15439 Multidrug resistance-associated protein 4 Unclassified protein C00030512 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00004533 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00004533 4 / 2
O60760 Hematopoietic prostaglandin D synthase Enzyme C00030512 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00004533 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00030512 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00030512 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00030512 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00030512 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00030512 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00030512 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00030512 0 / 0
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00030512 0 / 0
P15121 Aldose reductase Enzyme C00030512 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00030512 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00030512 0 / 0
P10145 Interleukin-8 Secreted protein C00030512 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00030512 1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00030512 0 / 0
P08311 Cathepsin G S1A C00030512 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00030512 1 / 0
P03956 Interstitial collagenase M10A C00030512 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00030512 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00030512 7 / 3
Q4U2R8 Solute carrier family 22 member 6 Antiporter C00030512 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00030512 1 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00030512 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00030512 0 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00030512 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00030512 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00004533 2 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00030512 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00030512 2 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00030512 5 / 3
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00030512 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00030512 1 / 0
P08246 Neutrophil elastase S1A C00030512 2 / 1
P21452 Substance-K receptor Neurokinin receptor C00030512 0 / 0
P06276 Cholinesterase Hydrolase C00004533 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00030512 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00030512 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00030512 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00030512 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00030512 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00030512 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00030512 2 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00030512 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00030512 0 / 3
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00030512 1 / 1
Q04828 Aldo-keto reductase family 1 member C1 Enzyme C00030512 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00030512 5 / 2
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00030512 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00004533 0 / 0
P06133 UDP-glucuronosyltransferase 2B4 Enzyme C00030512 0 / 0
P36537 UDP-glucuronosyltransferase 2B10 Enzyme C00030512 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00030512 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00030512 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00030512 1 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00030512 0 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00030512 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00030512 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00030512 0 / 0
Q99895 Chymotrypsin-C S1A C00030512 0 / 2
P21731 Thromboxane A2 receptor Prostanoid receptor C00030512 1 / 1
P25103 Substance-P receptor Neurokinin receptor C00030512 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00030512 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00030512 0 / 0
P34913 Bifunctional epoxide hydrolase 2 Serine protease S33 family C00030512 0 / 0
Q96FL8 Multidrug and toxin extrusion protein 1 Cation antiporter C00030512 0 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00030512 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00030512 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00030512 0 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00030512 1 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00030512 1 / 0
P52895 Aldo-keto reductase family 1 member C2 Enzyme C00030512 1 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00004533 5 / 1
P17516 Aldo-keto reductase family 1 member C4 Enzyme C00030512 1 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00030512 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00004533 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00030512 0 / 0
O75795 UDP-glucuronosyltransferase 2B17 Enzyme C00004533 1 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00030512 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00030512 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00030512 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00030512 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00030512 1 / 1
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00004533 3 / 0
Q04760 Lactoylglutathione lyase Enzyme C00030512 0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00030512 0 / 0
Q99685 Monoglyceride lipase Enzyme C00030512 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00030512 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00030512 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00030512 0 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00030512 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00030512 0 / 0
O95255 Multidrug resistance-associated protein 6 Unclassified protein C00030512 2 / 1
Q96QA9 Multidrug resistance associated protein Unclassified protein C00030512 0 / 0
Q9NSA0 Solute carrier family 22 member 11 Transporter C00030512 0 / 0
Q96J66 ATP-binding cassette sub-family C member 11 Unclassified protein C00030512 1 / 0
Q8WW43 Gamma-secretase subunit APH-1B Enzyme C00030512 0 / 0
P49768 Presenilin-1 A22A C00030512 4 / 4
Q96BI3 Gamma-secretase subunit APH-1A Enzyme C00030512 0 / 0
Q92542 Nicastrin Reg C00030512 1 / 1
Q9NZ42 Gamma-secretase subunit PEN-2 Enzyme C00030512 1 / 1
P49810 Presenilin-2 A22A C00030512 2 / 2
Q9NY46 Sodium channel protein type 3 subunit alpha SCN alpha, NaV1.x C00030512 0 / 0
Q99250 Sodium channel protein type 2 subunit alpha SCN alpha, NaV1.x C00030512 2 / 2
P35498 Sodium channel protein type 1 subunit alpha SCN alpha, NaV1.x C00030512 3 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00004533 0 / 0

336 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00004533 C00030512
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00004533 C00030512
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00004533 C00030512
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00004533 C00030512
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00004533 C00030512
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00004533 C00030512
57761 TRIB3, C20orf97, NIPK, SINK, SKIP3, TRB3 tribbles pseudokinase 3 C00030512
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00004533
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00004533
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00004533
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00004533
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00004533
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00004533
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00004533
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00004533
21 ABCA3, ABC-C, ABC3, EST111653, LBM180, SMDP3 ATP-binding cassette, sub-family A (ABC1), member 3 C00030512
8647 ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP ATP-binding cassette, sub-family B (MDR/TAP), member 11 C00030512
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00030512
8714 ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 C00030512
368 ABCC6, ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 C00030512
1636 ACE, ACE1, CD143, DCP, DCP1, ICH, MVCD3 angiotensin I converting enzyme (EC:3.4.15.1) C00030512
84519 ACRBP, CT23, OY-TES-1, SP32 acrosin binding protein C00030512
9510 ADAMTS1, C3-C5, METH1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 C00030512
9370 ADIPOQ, ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28 adiponectin, C1Q and collagen domain containing C00030512
23394 ADNP, ADNP1 activity-dependent neuroprotector homeobox C00030512
140 ADORA3, A3AR, AD026, bA552M11.5 adenosine A3 receptor C00030512
121536 AEBP2 AE binding protein 2 C00030512
183 AGT, ANHU, SERPINA8 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) C00030512
1645 AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) C00030512
1646 AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) C00030512
8644 AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) C00030512
1109 AKR1C4, 3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA aldo-keto reductase family 1, member C4 (EC:1.1.1.225 1.1.1.357) C00030512
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00030512
160428 ALDH1L2, mtFDH aldehyde dehydrogenase 1 family, member L2 (EC:1.5.1.6) C00030512
262 AMD1, ADOMETDC, AMD, SAMDC adenosylmethionine decarboxylase 1 (EC:4.1.1.50) C00030512
347902 AMIGO2, ALI1, AMIGO-2, DEGA adhesion molecule with Ig-like domain 2 C00030512
51129 ANGPTL4, ANGPTL2, ARP4, FIAF, HARP, HFARP, NL2, PGAR, UNQ171, pp1158 angiopoietin-like 4 C00030512
81573 ANKRD13C, RP4-677H15.5, dJ677H15.3 ankyrin repeat domain 13C C00030512
308 ANXA5, ANX5, ENX2, PP4, RPRGL3 annexin A5 C00030512
324 APC, BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 adenomatous polyposis coli C00030512
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00030512
8289 ARID1A, B120, BAF250, BAF250a, BM029, C1orf4, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1 AT rich interactive domain 1A (SWI-like) C00030512
84159 ARID5B, DESRT, MRF-2, MRF2 AT rich interactive domain 5B (MRF1-like) C00030512
10123 ARL4C, ARL7, LAK ADP-ribosylation factor-like 4C C00030512
57561 ARRDC3, TLIMP arrestin domain containing 3 C00030512
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00030512
22926 ATF6, ATF6A activating transcription factor 6 C00030512
521 ATP5I, ATP5K ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E (EC:3.6.1.14) C00030512
5205 ATP8B1, ATPIC, BRIC, FIC1, ICP1, PFIC, PFIC1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 (EC:3.6.3.1) C00030512
551 AVP, ADH, ARVP, AVP-NPII, AVRP, VP arginine vasopressin C00030512
23621 BACE1, ASP2, BACE, HSPC104 beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) C00030512
572 BAD, BBC2, BCL2L8 BCL2-associated agonist of cell death C00030512
578 BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 BCL2-antagonist/killer 1 C00030512
581 BAX, BCL2L4 BCL2-associated X protein C00030512
11177 BAZ1A, ACF1, WALp1, WCRF180, hACF1 bromodomain adjacent to zinc finger domain, 1A C00030512
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00030512
597 BCL2A1, ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1 BCL2-related protein A1 C00030512
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00030512
8553 BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14 basic helix-loop-helix family, member e40 C00030512
637 BID, FP497 BH3 interacting domain death agonist C00030512
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00030512
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00030512
55589 BMP2K, BIKE BMP2 inducible kinase (EC:2.7.11.1) C00030512
694 BTG1 B-cell translocation gene 1, anti-proliferative C00030512
11067 C10orf10, DEPP, FIG chromosome 10 open reading frame 10 C00030512
347744 C6orf52 chromosome 6 open reading frame 52 C00030512
759 CA1, CA-I, CAB, Car1 carbonic anhydrase I (EC:4.2.1.1) C00030512
760 CA2, CA-II, CAC, CAII, Car2 carbonic anhydrase II (EC:4.2.1.1) C00030512
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00030512
839 CASP6, MCH2 caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) C00030512
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00030512
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00030512
875 CBS, HIP4 cystathionine-beta-synthase (EC:4.2.1.22) C00030512
152137 CCDC50, C3orf6, DFNA44, YMER coiled-coil domain containing 50 C00030512
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00030512
6348 CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 chemokine (C-C motif) ligand 3 C00030512
6351 CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 chemokine (C-C motif) ligand 4 C00030512
891 CCNB1, CCNB cyclin B1 C00030512
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00030512
894 CCND2, KIAK0002 cyclin D2 C00030512
901 CCNG2 cyclin G2 C00030512
9236 CCPG1, CPR8 cell cycle progression 1 C00030512
1232 CCR3, CC-CKR-3, CD193, CKR3, CMKBR3 chemokine (C-C motif) receptor 3 C00030512
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00030512
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00030512
1019 CDK4, CMM3, PSK-J3 cyclin-dependent kinase 4 (EC:2.7.11.22) C00030512
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00030512
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00030512
8837 CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS CASP8 and FADD-like apoptosis regulator C00030512
1082 CGB, CGB3, CGB5, CGB7, CGB8, hCGB chorionic gonadotropin, beta polypeptide C00030512
79094 CHAC1 ChaC, cation transport regulator homolog 1 (E. coli) C00030512
1105 CHD1 chromodomain helicase DNA binding protein 1 (EC:3.6.4.12) C00030512
63924 CIDEC, CIDE-3, CIDE3, FPLD5, FSP27 cell death-inducing DFFA-like effector c C00030512
10370 CITED2, ASD8, MRG-1, MRG1, P35SRJ, VSD2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 C00030512
1277 COL1A1, OI4 collagen, type I, alpha 1 C00030512
11052 CPSF6, CFIM, CFIM68, HPBRII-4, HPBRII-7 cleavage and polyadenylation specific factor 6, 68kDa C00030512
1389 CREBL2 cAMP responsive element binding protein-like 2 C00030512
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00030512
79848 CSPP1, CSPP centrosome and spindle pole associated protein 1 C00030512
1491 CTH cystathionase (cystathionine gamma-lyase) (EC:4.4.1.1) C00030512
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00030512
1508 CTSB, APPS, CPSB cathepsin B (EC:3.4.22.1) C00030512
3627 CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 chemokine (C-X-C motif) ligand 10 C00030512
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00030512
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00030512
1649 DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 DNA-damage-inducible transcript 3 C00030512
11083 DIDO1, BYE1, C20orf158, DATF-1, DATF1, DIDO2, DIDO3, DIO-1, DIO1, dJ885L7.8 death inducer-obliterator 1 C00030512
10294 DNAJA2, CPR3, DJ3, DJA2, DNAJ, DNJ3, HIRIP4, PRO3015, RDJ2 DnaJ (Hsp40) homolog, subfamily A, member 2 C00030512
3338 DNAJC4, DANJC4, HSPF2, MCG18 DnaJ (Hsp40) homolog, subfamily C, member 4 C00030512
667 DST, BP240, BPA, BPAG1, CATX-15, CATX15, D6S1101, DMH, DT, EBSB2, HSAN6, MACF2 dystonin C00030512
1843 DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10 dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) C00030512
1848 DUSP6, HH19, MKP3, PYST1 dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48) C00030512
1871 E2F3, E2F-3 E2F transcription factor 3 C00030512
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00030512
1910 EDNRB, ABCDS, ET-B, ET-BR, ETB, ETBR, ETRB, HSCR, HSCR2, WS4A endothelin receptor type B C00030512
23167 EFR3A EFR3 homolog A (S. cerevisiae) C00030512
1950 EGF, HOMG4, URG epidermal growth factor C00030512
1958 EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 early growth response 1 C00030512
1964 EIF1AX, EIF1A, EIF1AP1, EIF4C, eIF-1A, eIF-4C eukaryotic translation initiation factor 1A, X-linked C00030512
2150 F2RL1, GPR11, PAR2 coagulation factor II (thrombin) receptor-like 1 C00030512
2152 F3, CD142, TF, TFA coagulation factor III (thromboplastin, tissue factor) C00030512
2167 FABP4, A-FABP, AFABP, ALBP, aP2 fatty acid binding protein 4, adipocyte C00030512
26190 FBXW2, FBW2, Fwd2, Md6 F-box and WD repeat domain containing 2 C00030512
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00030512
94234 FOXQ1, HFH1 forkhead box Q1 C00030512
8324 FZD7, FzE3 frizzled family receptor 7 C00030512
4616 GADD45B, GADD45BETA, MYD118 growth arrest and DNA-damage-inducible, beta C00030512
2627 GATA6 GATA binding protein 6 C00030512
2633 GBP1 guanylate binding protein 1, interferon-inducible C00030512
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00030512
2730 GCLM, GLCLR glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) C00030512
9518 GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB growth differentiation factor 15 C00030512
2744 GLS, AAD20, GAC, GAM, GLS1, KGA glutaminase (EC:3.5.1.2) C00030512
2752 GLUL, GLNS, GS, PIG43, PIG59 glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2) C00030512
57531 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 C00030512
256158 HMCN2 hemicentin 2 C00030512
3248 HPGD, 15-PGDH, PGDH, PGDH1, PHOAR1, SDR36C1 hydroxyprostaglandin dehydrogenase 15-(NAD) (EC:1.1.1.141) C00030512
3291 HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3 hydroxysteroid (11-beta) dehydrogenase 2 (EC:1.1.1.146) C00030512
3297 HSF1, HSTF1 heat shock transcription factor 1 C00030512
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00030512
3309 HSPA5, BIP, GRP78, MIF2 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) C00030512
3312 HSPA8, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, NIP71 heat shock 70kDa protein 8 C00030512
3458 IFNG, IFG, IFI interferon, gamma C00030512
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00030512
3589 IL11, AGIF, IL-11 interleukin 11 C00030512
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00030512
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00030512
3557 IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4 interleukin 1 receptor antagonist C00030512
3558 IL2, IL-2, TCGF, lymphokine interleukin 2 C00030512
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00030512
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00030512
3572 IL6ST, CD130, CDW130, GP130, IL-6RB interleukin 6 signal transducer (gp130, oncostatin M receptor) C00030512
3574 IL7, IL-7 interleukin 7 C00030512
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00030512
3630 INS, IDDM2, ILPR, IRDN, MODY10 insulin C00030512
3843 IPO5, IMB3, KPNB3, Pse1, RANBP5, imp5 importin 5 C00030512
81875 ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 C00030512
3684 ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6 integrin, alpha M (complement component 3 receptor 3 subunit) C00030512
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00030512
3726 JUNB, AP-1 jun B proto-oncogene C00030512
115207 KCTD12, C13orf2, PFET1, PFETIN potassium channel tetramerization domain containing 12 C00030512
9817 KEAP1, INrf2, KLHL19 kelch-like ECH-associated protein 1 C00030512
55196 C12orf35 KIAA1551 C00030512
9314 KLF4, EZF, GKLF Kruppel-like factor 4 (gut) C00030512
3827 KNG1, BDK, BK, KNG kininogen 1 C00030512
3915 LAMC1, LAMB2 laminin, gamma 1 (formerly LAMB2) C00030512
81606 LBH limb bud and heart development C00030512
3949 LDLR, FH, FHC, LDLCQ2 low density lipoprotein receptor C00030512
3952 LEP, LEPD, OB, OBS leptin C00030512
4023 LPL, HDLCQ11, LIPD lipoprotein lipase (EC:3.1.1.34) C00030512
4049 LTA, LT, TNFB, TNFSF1 lymphotoxin alpha C00030512
4067 LYN, JTK8, p53Lyn, p56Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) C00030512
6416 MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1 mitogen-activated protein kinase kinase 4 (EC:2.7.12.2) C00030512
9448 MAP4K4, FLH21957, HGK, MEKKK4, NIK mitogen-activated protein kinase kinase kinase kinase 4 (EC:2.7.11.1) C00030512
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00030512
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00030512
4154 MBNL1, EXP, EXP35, EXP40, EXP42, MBNL muscleblind-like splicing regulator 1 C00030512
4155 MBP myelin basic protein C00030512
124512 METTL23, C17orf95 methyltransferase like 23 C00030512
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00030512
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00030512
6307 MSMO1, DESP4, ERG25, SC4MOL methylsterol monooxygenase 1 (EC:1.14.13.72) C00030512
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00030512
4739 NEDD9, CAS-L, CAS2, CASL, CASS2, HEF1 neural precursor cell expressed, developmentally down-regulated 9 C00030512
10276 NET1, ARHGEF8, NET1A neuroepithelial cell transforming 1 C00030512
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00030512
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00030512
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00030512
4803 NGF, Beta-NGF, HSAN5, NGFB nerve growth factor (beta polypeptide) C00030512
57224 NHSL1, C6orf63 NHS-like 1 C00030512
4824 NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A NK3 homeobox 1 C00030512
4830 NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1 NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6) C00030512
4869 NPM1, B23, NPM nucleophosmin (nucleolar phosphoprotein B23, numatrin) C00030512
4878 NPPA, ANF, ANP, ATFB6, CDD-ANF, PND natriuretic peptide A C00030512
7026 NR2F2, ARP1, COUPTFB, COUPTFII, NF-E3, NR2F1, SVP40, TFCOUP2 nuclear receptor subfamily 2, group F, member 2 C00030512
3164 NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3 nuclear receptor subfamily 4, group A, member 1 C00030512
4897 NRCAM neuronal cell adhesion molecule C00030512
4907 NT5E, CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT 5'-nucleotidase, ecto (CD73) (EC:3.1.3.5) C00030512
9891 NUAK1, ARK5 NUAK family, SNF1-like kinase, 1 (EC:2.7.11.1) C00030512
57532 NUFIP2, 182-FIP, 82-FIP, FIP-82 nuclear fragile X mental retardation protein interacting protein 2 C00030512
8106 PABPN1, OPMD, PAB2, PABII, PABP-2, PABP2 poly(A) binding protein, nuclear 1 C00030512
53354 PANK1, PANK pantothenate kinase 1 (EC:2.7.1.33) C00030512
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00030512
5111 PCNA proliferating cell nuclear antigen C00030512
54704 PDP1, PDH, PDP, PDPC, PPM2C pyruvate dehyrogenase phosphatase catalytic subunit 1 (EC:3.1.3.43) C00030512
9867 PJA2, Neurodap1, RNF131 praja ring finger 2, E3 ubiquitin protein ligase (EC:6.3.2.-) C00030512
8502 PKP4, p0071 plakophilin 4 C00030512
5328 PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA plasminogen activator, urokinase (EC:3.4.21.73) C00030512
123 PLIN2, ADFP, ADRP perilipin 2 C00030512
10769 PLK2, SNK, hPlk2, hSNK polo-like kinase 2 (EC:2.7.11.21) C00030512
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00030512
56937 PMEPA1, STAG1, TMEPAI prostate transmembrane protein, androgen induced 1 C00030512
5465 PPARA, NR1C1, PPAR, PPARalpha, hPPAR peroxisome proliferator-activated receptor alpha C00030512
5467 PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB peroxisome proliferator-activated receptor delta C00030512
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00030512
151987 PPP4R2, PP4R2 protein phosphatase 4, regulatory subunit 2 C00030512
5579 PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 protein kinase C, beta (EC:2.7.11.13) C00030512
5581 PRKCE, PKCE, nPKC-epsilon protein kinase C, epsilon (EC:2.7.11.13) C00030512
5583 PRKCH, PKC-L, PKCL, PRKCL, nPKC-eta protein kinase C, eta (EC:2.7.11.13) C00030512
5584 PRKCI, DXS1179E, PKCI, nPKC-iota protein kinase C, iota (EC:2.7.11.13) C00030512
8899 PRPF4B, PR4H, PRP4, PRP4H, PRP4K, dJ1013A10.1 pre-mRNA processing factor 4B (EC:2.7.11.1) C00030512
5723 PSPH, PSP, PSPHD phosphoserine phosphatase (EC:3.1.3.3) C00030512
11251 PTGDR2, CD294, CRTH2, DL1R, DP2, GPR44 prostaglandin D2 receptor 2 C00030512
5732 PTGER2, EP2 prostaglandin E receptor 2 (subtype EP2), 53kDa C00030512
5742 PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00030512
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00030512
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK protein tyrosine kinase 2 (EC:2.7.10.2) C00030512
5782 PTPN12, PTP-PEST, PTPG1 protein tyrosine phosphatase, non-receptor type 12 (EC:3.1.3.48) C00030512
221749 PXDC1, C6orf145 PX domain containing 1 C00030512
5887 RAD23B, HHR23B, HR23B, P58 RAD23 homolog B (S. cerevisiae) C00030512
51735 RAPGEF6, KIA001LB, PDZ-GEF2, PDZGEF2, RA-GEF-2, RAGEF2 Rap guanine nucleotide exchange factor (GEF) 6 C00030512
65059 RAPH1, ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 C00030512
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00030512
64783 RBM15, OTT, OTT1, SPEN RNA binding motif protein 15 C00030512
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00030512
5972 REN, HNFJ2 renin (EC:3.4.23.15) C00030512
51455 REV1, REV1L REV1, polymerase (DNA directed) C00030512
388 RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 ras homolog family member B C00030512
255488 RNF144B, IBRDC2, PIR2, bA528A10.3, p53RFP ring finger protein 144B C00030512
153830 RNF145 ring finger protein 145 C00030512
9475 ROCK2, ROCK-II Rho-associated, coiled-coil containing protein kinase 2 (EC:2.7.11.1) C00030512
6256 RXRA, NR2B1 retinoid X receptor, alpha C00030512
6299 SALL1, HSAL1, Sal-1, TBS, ZNF794 spalt-like transcription factor 1 C00030512
6301 SARS, SERRS, SERS seryl-tRNA synthetase (EC:6.1.1.11) C00030512
6303 SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1 spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) C00030512
11341 SCRG1, SCRG-1 stimulator of chondrogenesis 1 C00030512
11231 SEC63, DNAJC23, ERdj2, PRO2507, SEC63L SEC63 homolog (S. cerevisiae) C00030512
6402 SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1 selectin L C00030512
5265 SERPINA1, A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 C00030512
5054 SERPINE1, PAI, PAI-1, PAI1, PLANH1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 C00030512
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00030512
6573 SLC19A1, CHMD, FOLT, IFC1, REFC, RFC1 solute carrier family 19 (folate transporter), member 1 C00030512
10560 SLC19A2, TC1, THMD1, THT1, THTR1, TRMA solute carrier family 19 (thiamine transporter), member 2 C00030512
6580 SLC22A1, HOCT1, OCT1, oct1_cds solute carrier family 22 (organic cation transporter), member 1 C00030512
55867 SLC22A11, OAT4, hOAT4 solute carrier family 22 (organic anion/urate transporter), member 11 C00030512
116085 SLC22A12, OAT4L, RST, URAT1 solute carrier family 22 (organic anion/urate transporter), member 12 C00030512
6582 SLC22A2, OCT2 solute carrier family 22 (organic cation transporter), member 2 C00030512
9356 SLC22A6, HOAT1, OAT1, PAHT, ROAT1 solute carrier family 22 (organic anion transporter), member 6 C00030512
10864 SLC22A7, NLT, OAT2 solute carrier family 22 (organic anion transporter), member 7 C00030512
9376 SLC22A8, OAT3 solute carrier family 22 (organic anion transporter), member 8 C00030512
114571 SLC22A9, HOAT4, OAT4, OAT7, UST3H, ust3 solute carrier family 22 (organic anion transporter), member 9 C00030512
9962 SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2 solute carrier family 23 (ascorbic acid transporter), member 2 C00030512
6520 SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE solute carrier family 3 (amino acid transporter heavy chain), member 2 C00030512
23657 SLC7A11, CCBR1, xCT solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 C00030512
6578 SLCO2A1, MATR1, OATP2A1, PGT, PHOAR2, SLC21A2 solute carrier organic anion transporter family, member 2A1 C00030512
4092 SMAD7, CRCS3, MADH7, MADH8 SMAD family member 7 C00030512
6591 SNAI2, SLUG, SLUGH1, SNAIL2, WS2D snail family zinc finger 2 C00030512
9655 SOCS5, CIS6, CISH6, Cish5, SOCS-5 suppressor of cytokine signaling 5 C00030512
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00030512
6651 SON, BASS1, C21orf50, DBP-5, NREBP, SON3 SON DNA binding protein C00030512
54345 SOX18, HLTS SRY (sex determining region Y)-box 18 C00030512
83595 SOX7 SRY (sex determining region Y)-box 7 C00030512
30014 SPANXA1, CT11.1, NAP-X, SPAN-Xa, SPAN-Xb, SPANX sperm protein associated with the nucleus, X-linked, family member A1 C00030512
132671 SPATA18, Mieap, SPETEX1 spermatogenesis associated 18 C00030512
221409 SPATS1, DDIP, SPATA8, SRSP1 spermatogenesis associated, serine-rich 1 C00030512
6431 SRSF6, B52, SFRS6, SRP55 serine/arginine-rich splicing factor 6 C00030512
6772 STAT1, CANDF7, ISGF-3, STAT91 signal transducer and activator of transcription 1, 91kDa C00030512
6781 STC1, STC stanniocalcin 1 C00030512
6934 TCF7L2, TCF-4, TCF4 transcription factor 7-like 2 (T-cell specific, HMG-box) C00030512
6996 TDG, hTDG thymine-DNA glycosylase (EC:3.2.2.29) C00030512
7037 TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 transferrin receptor C00030512
96764 TGS1, NCOA6IP, PIMT, PIPMT trimethylguanosine synthase 1 (EC:2.1.1.-) C00030512
7056 THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM thrombomodulin C00030512
7057 THBS1, THBS, THBS-1, TSP, TSP-1, TSP1 thrombospondin 1 C00030512
7076 TIMP1, CLGI, EPA, EPO, HCI, TIMP TIMP metallopeptidase inhibitor 1 C00030512
23671 TMEFF2, CT120.2, HPP1, TENB2, TPEF, TR transmembrane protein with EGF-like and two follistatin-like domains 2 C00030512
65062 TMEM237, ALS2CR4, JBTS14 transmembrane protein 237 C00030512
7114 TMSB4X, FX, PTMB4, TB4X, TMSB4 thymosin beta 4, X-linked C00030512
83857 TMTC1, OLF, TMTC1A transmembrane and tetratricopeptide repeat containing 1 C00030512
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00030512
27242 TNFRSF21, BM-018, CD358, DR6 tumor necrosis factor receptor superfamily, member 21 C00030512
10140 TOB1, APRO6, PIG49, TOB, TROB, TROB1 transducer of ERBB2, 1 C00030512
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00030512
7164 TPD52L1, D53, hD53 tumor protein D52-like 1 C00030512
2034 EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 endothelial PAS domain protein 1 C00004533
10626 TRIM16, EBBP tripartite motif containing 16 C00030512
6738 TROVE2, RO60, RORNP, SSA2 TROVE domain family, member 2 C00030512
8848 TSC22D1, Ptg-2, TGFB1I4, TSC22 TSC22 domain family, member 1 C00030512
51175 TUBE1, TUBE, dJ142L7.2 tubulin, epsilon 1 C00030512
10426 TUBGCP3, 104p, GCP3, Grip104, SPBC98, Spc98, Spc98p tubulin, gamma complex associated protein 3 C00030512
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00030512
10628 TXNIP, EST01027, HHCPA78, THIF, VDUP1 thioredoxin interacting protein C00030512
23350 U2SURP, SR140, fSAPa U2 snRNP-associated SURP domain containing C00030512
134510 UBLCP1, CPUB1 ubiquitin-like domain containing CTD phosphatase 1 (EC:3.1.3.16) C00030512
51366 UBR5, DD5, EDD, EDD1, HYD ubiquitin protein ligase E3 component n-recognin 5 C00030512
7351 UCP2, BMIQ4, SLC25A8, UCPH uncoupling protein 2 (mitochondrial, proton carrier) C00030512
7357 UGCG, GCS, GLCT1 UDP-glucose ceramide glucosyltransferase (EC:2.4.1.80) C00030512
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00030512
54657 UGT1A4, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D UDP glucuronosyltransferase 1 family, polypeptide A4 (EC:2.4.1.17) C00030512
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00030512
10941 UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (EC:2.4.1.17) C00030512
7364 UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9 UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17) C00030512
133688 UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 (EC:2.4.1.17) C00030512
7378 UPP1, UDRPASE, UP, UPASE, UPP uridine phosphorylase 1 (EC:2.4.2.3) C00030512
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00030512
81671 VMP1, EPG3, TANGO5, TMEM49 vacuole membrane protein 1 C00030512
23063 WAPAL, FOE, KIAA0261, WAPL wings apart-like homolog (Drosophila) C00030512
8840 WISP1, CCN4, WISP1c, WISP1i, WISP1tc WNT1 inducible signaling pathway protein 1 C00030512
7494 XBP1, TREB5, XBP-1, XBP2 X-box binding protein 1 C00030512
7498 XDH, XO, XOR xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) C00030512
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00030512
55432 YOD1, DUBA8, OTUD2, PRO0907 YOD1 deubiquitinase (EC:3.4.19.12) C00030512
51441 YTHDF2, HGRG8, NY-REN-2 YTH domain family, member 2 C00030512
253943 YTHDF3 YTH domain family, member 3 C00030512
7531 YWHAE, 14-3-3E, KCIP-1, MDCR, MDS tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide C00030512
27107 ZBTB11, ZNF-U69274, ZNF913 zinc finger and BTB domain containing 11 C00030512
10472 ZBTB18, C2H2-171, RP58, TAZ-1, ZNF238 zinc finger and BTB domain containing 18 C00030512
360023 ZBTB41, FRBZ1, RP11-469L3.1, ZNF924 zinc finger and BTB domain containing 41 C00030512
29068 ZBTB44, BTBD15, HSPC063, ZNF851 zinc finger and BTB domain containing 44 C00030512
23091 ZC3H13, KIAA0853 zinc finger CCCH-type containing 13 C00030512
56829 ZC3HAV1, ARTD13, FLB6421, PARP13, ZAP, ZC3H2, ZC3HDC2 zinc finger CCCH-type, antiviral 1 C00030512
92092 ZC3HAV1L, C7orf39 zinc finger CCCH-type, antiviral 1-like C00030512
6935 ZEB1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A zinc finger E-box binding homeobox 1 C00030512
7707 ZNF148, BERF-1, BFCOL1, HT-BETA, ZBP-89, ZFP148, pHZ-52 zinc finger protein 148 C00030512
57541 ZNF398, P51, P71, ZER6 zinc finger protein 398 C00030512
54680 ZNHIT6, BCD1, C1orf181, NY-BR-75 zinc finger, HIT-type containing 6 C00030512

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (125)

OMIM preferred title UniProt
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#142690 Acne inversa, familial, 1; acninv1 Q92542
#613736 Acne inversa, familial, 2; acninv2 Q9NZ42
#613737 Acne inversa, familial, 3; acninv3 P49768
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#103780 Alcohol dependence P08172
P14416
P31645
#607822 Alzheimer disease 3 P49768
#606889 Alzheimer disease 4 P49810
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#117800 Apocrine gland secretion, variation in Q96J66
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614473 Arterial calcification, generalized, of infancy, 2; gaci2 O95255
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614009 Bleeding disorder, platelet-type, 13, susceptibility to; bdplt13 P21731
#614490 Blood group, junior system; jr Q9UNQ0
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#612560 Bone mineral density quantitative trait locus 12; bmnd12 O75795
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#613694 Cardiomyopathy, dilated, 1u; cmd1u P49768
#613697 Cardiomyopathy, dilated, 1v; cmd1v P49810
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P84022
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#607208 Dravet syndrome P35498
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#613721 Epileptic encephalopathy, early infantile, 11; eiee11 Q99250
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
P49768
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#604403 Generalized epilepsy with febrile seizures plus, type 2; gefsp2 P35498
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 P04626
P37231
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#145000 Hyperparathyroidism 1; hrpt1 O00255
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#601626 Leukemia, acute myeloid; aml P36888
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#609634 Migraine, familial hemiplegic, 3; fhm3 P35498
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#264800 Pseudoxanthoma elasticum; pxe O95255
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#607745 Seizures, benign familial infantile, 3; bfis3 Q99250
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#112100 Yt blood group antigen P22303

KEGG DISEASE (87)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00560 Pseudoxanthoma elasticum O95255 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
P49768 (related)
P49810 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
P38398 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P38398 (related)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
P49768 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H01235 Bleeding disorder platelet-type P21731 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00775 Familial or sporadic hemiplegic migraine P35498 (related)
H00783 Febrile seizures P35498 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00192 Xanthinuria P47989 (related)
H00056 Alzheimer's disease (AD) P49768 (related)
P49810 (related)
H00681 Acne inversa P49768 (related)
Q92542 (related)
Q9NZ42 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00606 Early infantile epileptic encephalopathy Q99250 (related)
H00806 Benign familial neonatal and infantile epilepsies Q99250 (related)
H00932 Tropical calcific pancreatitis Q99895 (related)
H00933 Hereditary pancreatitis Q99895 (related)

Diseases related to CTD interactions

275 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006943 Hyperglycemia C00004533
D006946 Hyperinsulinism C00004533
D015228 Hypertriglyceridemia C00004533
D007333 Insulin Resistance C00004533
D015746 Abdominal Pain C00030512
D058186 Acute Kidney Injury C00030512
D000230 Adenocarcinoma C00030512
D000236 Adenoma C00030512
D000380 Agranulocytosis C00030512
D016301 Alveolar Bone Loss C00030512
D000544 Alzheimer Disease C00030512
D000707 Anaphylaxis C00030512
D000740 Anemia C00030512
D000741 Anemia, Aplastic C00030512
D000743 Anemia, Hemolytic C00030512
D018798 Anemia, Iron-Deficiency C00030512
D000783 Aneurysm C00030512
D000787 Angina Pectoris C00030512
D000799 Angioedema C00030512
D000855 Anorexia C00030512
D000860 Anoxia C00030512
D001002 Anuria C00030512
D001008 Anxiety Disorders C00030512
D001014 Aortic Aneurysm C00030512
D017544 Aortic Aneurysm, Abdominal C00030512
D018771 Arthralgia C00030512
D001168 Arthritis C00030512
D015210 Arthritis, Gouty C00030512
D001170 Arthritis, Infectious C00030512
D001171 Arthritis, Juvenile C00030512
D001172 Arthritis, Rheumatoid C00030512
D001201 Ascites C00030512
D001265 Athletic Injuries C00030512
D053099 Azotemia C00030512
D001477 Bartter Syndrome C00030512
D001714 Bipolar Disorder C00030512
D001919 Bradycardia C00030512
D001927 Brain Diseases C00030512
D001929 Brain Edema C00030512
D001930 Brain Injuries C00030512
D002545 Brain Ischemia C00030512
D001932 Brain Neoplasms C00030512
D001943 Breast Neoplasms C00030512
D001997 Bronchopulmonary Dysplasia C00030512
D002056 Burns C00030512
D002100 Cachexia C00030512
D006528 Carcinoma, Hepatocellular C00030512
D018827 Carcinoma, Lewis Lung C00030512
D018276 Carcinoma, Medullary C00030512
D002292 Carcinoma, Renal Cell C00030512
D002294 Carcinoma, Squamous Cell C00030512
D006332 Cardiomegaly C00030512
D018376 Cardiovascular Abnormalities C00030512
D002318 Cardiovascular Diseases C00030512
D002375 Catalepsy C00030512
D002429 Cecal Diseases C00030512
D002493 Central Nervous System Diseases C00030512
D002543 Cerebral Hemorrhage C00030512
D002764 Cholecystitis C00030512
D002779 Cholestasis C00030512
D002780 Cholestasis, Intrahepatic C00030512
D002805 Chondrocalcinosis C00030512
D003027 Cluster Headache C00030512
D003072 Cognition Disorders C00030512
D003110 Colonic Neoplasms C00030512
D015179 Colorectal Neoplasms C00030512
D003128 COMA C00030512
D003221 Confusion C00030512
D003229 Conjunctival Diseases C00030512
D003244 Consciousness Disorders C00030512
D003251 Constriction, Pathologic C00030512
D054059 Coronary Occlusion C00030512
D003329 Coronary Vasospasm C00030512
D018352 Coronavirus Infections C00030512
D003556 Cystitis C00030512
D018856 Cystitis, Interstitial C00030512
D003693 Delirium C00030512
D018500 Diabetes Insipidus, Nephrogenic C00030512
D003967 Diarrhea C00030512
D004211 Disseminated Intravascular Coagulation C00030512
D004213 Dissociative Disorders C00030512
D004244 Dizziness C00030512
D003875 Drug Eruptions C00030512
D004342 Drug Hypersensitivity C00030512
D056486 Drug-Induced Liver Injury C00030512
D004374 Ductus Arteriosus, Patent C00030512
D004381 Duodenal Ulcer C00030512
D004409 Dyskinesia, Drug-Induced C00030512
D004412 Dysmenorrhea C00030512
D004415 Dyspepsia C00030512
D020920 Dyssomnias C00030512
D004487 Edema C00030512
D004715 Endometriosis C00030512
D019446 Endotoxemia C00030512
D004751 Enteritis C00030512
D020345 Enterocolitis, Necrotizing C00030512
D004802 Eosinophilia C00030512
D004938 Esophageal Neoplasms C00030512
D005076 Exanthema C00030512
D005119 Extravasation of Diagnostic and Therapeutic Materials C00030512
D005198 Fanconi Syndrome C00030512
D005315 Fetal Diseases C00030512
D005317 Fetal Growth Retardation C00030512
D005334 Fever C00030512
D005354 Fibrosarcoma C00030512
D005355 Fibrosis C00030512
D005499 Folliculitis C00030512
D005756 Gastritis C00030512
D005767 Gastrointestinal Diseases C00030512
D006471 Gastrointestinal Hemorrhage C00030512
D005909 Glioblastoma C00030512
D005910 Glioma C00030512
D005921 Glomerulonephritis C00030512
D005923 Glomerulosclerosis, Focal Segmental C00030512
D006042 Goiter C00030512
D006073 Gout C00030512
D006099 Granuloma C00030512
D006212 Hallucinations C00030512
D006261 Headache C00030512
D020773 Headache Disorders C00030512
D006258 Head and Neck Neoplasms C00030512
D006319 Hearing Loss, Sensorineural C00030512
D006356 Heartburn C00030512
D006330 Heart Defects, Congenital C00030512
D006331 Heart Diseases C00030512
D006333 Heart Failure C00030512
D006396 Hematemesis C00030512
D006417 Hematuria C00030512
D006470 Hemorrhage C00030512
D006501 Hepatic Encephalopathy C00030512
D019693 Hepatitis, Autoimmune C00030512
D006509 Hepatitis B C00030512
D019698 Hepatitis C, Chronic C00030512
D015160 Hydrops Fetalis C00030512
D006930 Hyperalgesia C00030512
D034321 Hyperamylasemia C00030512
D006934 Hypercalcemia C00030512
D006940 Hyperemia C00030512
D006941 Hyperesthesia C00030512
D006947 Hyperkalemia C00030512
D006949 Hyperlipidemias C00030512
D006955 Hypernatremia C00030512
D006965 Hyperplasia C00030512
D006973 Hypertension C00030512
D006976 Hypertension, Pulmonary C00030512
D006977 Hypertension, Renal C00030512
D017379 Hypertrophy, Left Ventricular C00030512
D017380 Hypertrophy, Right Ventricular C00030512
D034141 Hypoalbuminemia C00030512
D006994 Hypoaldosteronism C00030512
D007008 Hypokalemia C00030512
D007010 Hyponatremia C00030512
D007022 Hypotension C00030512
D007024 Hypotension, Orthostatic C00030512
D007077 Ileal Diseases C00030512
D007079 Ileitis C00030512
D007177 Inappropriate ADH Syndrome C00030512
D007232 Infant, Newborn, Diseases C00030512
D007235 Infant, Premature, Diseases C00030512
D007249 Inflammation C00030512
D007410 Intestinal Diseases C00030512
D007414 Intestinal Neoplasms C00030512
D007416 Intestinal Perforation C00030512
D007417 Intestinal Polyps C00030512
D020300 Intracranial Hemorrhages C00030512
D019586 Intracranial Hypertension C00030512
D007511 Ischemia C00030512
D007565 Jaundice C00030512
D007579 Jejunal Diseases C00030512
D007674 Kidney Diseases C00030512
D052177 Kidney Diseases, Cystic C00030512
D007676 Kidney Failure, Chronic C00030512
D007680 Kidney Neoplasms C00030512
D007681 Kidney Papillary Necrosis C00030512
D007683 Kidney Tubular Necrosis, Acute C00030512
D016773 Leishmaniasis, Cutaneous C00030512
D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive C00030512
D015470 Leukemia, Myeloid, Acute C00030512
D007964 Leukocytosis C00030512
D007969 Leukomalacia, Periventricular C00030512
D007970 Leukopenia C00030512
D007984 Leydig Cell Tumor C00030512
D008101 Liver Abscess, Amebic C00030512
D008103 Liver Cirrhosis C00030512
D008106 Liver Cirrhosis, Experimental C00030512
D008107 Liver Diseases C00030512
D008113 Liver Neoplasms C00030512
D008171 Lung Diseases C00030512
D008175 Lung Neoplasms C00030512
D008180 Lupus Erythematosus, Systemic C00030512
D015674 Mammary Neoplasms, Animal C00030512
D008415 Mastocytosis C00030512
D008581 Meningitis C00030512
D001523 Mental Disorders C00030512
D008881 Migraine Disorders C00030512
D028361 Mitochondrial Diseases C00030512
D009062 Mouth Neoplasms C00030512
D009325 Nausea C00030512
D009336 Necrosis C00030512
D009362 Neoplasm Metastasis C00030512
D009374 Neoplasms, Experimental C00030512
D009395 Nephritis, Interstitial C00030512
D009401 Nephrosis C00030512
D009404 Nephrotic Syndrome C00030512
D019636 Neurodegenerative Diseases C00030512
D007752 Obstetric Labor, Premature C00030512
D016104 Oligohydramnios C00030512
D009846 Oliguria C00030512
D009999 Ossification, Heterotopic C00030512
D010003 Osteoarthritis C00030512
D015207 Osteoarthritis, Hip C00030512
D016471 Ovarian Hyperstimulation Syndrome C00030512
D010146 Pain C00030512
D010149 Pain, Postoperative C00030512
D010195 Pancreatitis C00030512
D010257 Paraneoplastic Syndromes C00030512
D020734 Parkinsonian Disorders C00030512
D051302 Paroxysmal Hemicrania C00030512
D010437 Peptic Ulcer C00030512
D010490 Pericardial Effusion C00030512
D010493 Pericarditis C00030512
D010518 Periodontitis C00030512
D010523 Peripheral Nervous System Diseases C00030512
D010547 Persistent Fetal Circulation Syndrome C00030512
D010996 Pleural Effusion C00030512
D011014 Pneumonia C00030512
D006831 Polyhydramnios C00030512
D011141 Polyuria C00030512
D047928 Premature Birth C00030512
D011507 Proteinuria C00030512
D011546 Pseudohypoaldosteronism C00030512
D011559 Pseudotumor Cerebri C00030512
D011605 Psychoses, Substance-Induced C00030512
D011654 Pulmonary Edema C00030512
D011660 Pulmonary Heart Disease C00030512
D011693 Purpura C00030512
D011704 Pyelonephritis C00030512
D011928 Raynaud Disease C00030512
D012021 Reflex, Abnormal C00030512
D056844 Renal Colic C00030512
D051437 Renal Insufficiency C00030512
D051436 Renal Insufficiency, Chronic C00030512
D015427 Reperfusion Injury C00030512
D012216 Rheumatic Diseases C00030512
D012585 Sciatica C00030512
D012640 Seizures C00030512
D018805 Sepsis C00030512
D012735 Sexual Dysfunction, Physiological C00030512
D012871 Skin Diseases C00030512
D012893 Sleep Disorders C00030512
D013119 Spinal Cord Injuries C00030512
D013167 Spondylitis, Ankylosing C00030512
D013226 Status Epilepticus C00030512
D013272 Stomach Diseases C00030512
D013274 Stomach Neoplasms C00030512
D013276 Stomach Ulcer C00030512
D013610 Tachycardia C00030512
D052256 Tendinopathy C00030512
D013921 Thrombocytopenia C00030512
D013964 Thyroid Neoplasms C00030512
D014202 Tremor C00030512
D014262 Tricuspid Valve Insufficiency C00030512
D014456 Ulcer C00030512
D014511 Uremia C00030512
D014514 Ureteral Calculi C00030512
D001745 Urinary Bladder Diseases C00030512
D001749 Urinary Bladder Neoplasms C00030512
D014571 Urologic Neoplasms C00030512
D014581 Urticaria C00030512
D014652 Vascular Diseases C00030512
D018366 Vasculitis, Leukocytoclastic, Cutaneous C00030512
D020301 Vasospasm, Intracranial C00030512
D018497 Ventricular Dysfunction, Right C00030512
D014717 Vertigo C00030512
D014839 Vomiting C00030512