Species

KNApSAcK Entry

Organism name Ononis natrix
Genus Ononis
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ononis natrix
Linked NCBI taxonomy ID 200954
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005182 External link 512 Kaempferol 3,7-diglucoside
/ Kaempferol 3,7-O-beta-D-diglucopyranoside
CHEMBL2206209
No. 1 No. 15
C00001075 External link 512 Nevadensin
CHEMBL312073
C023982
1 / 0 / 0 No. 3 No. 15
C00003879 External link 512 Xanthomicrol
/ 5-Hydroxy-2-(4-hydroxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL476121
C462036
No. 3 No. 15
C00003876 External link 512 Desmethoxysudachitin
/ 5,7,4'-Trihydroxy-6,8-dimethoxyflavone
/ 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one
CHEMBL476120
C078367
No. 3 No. 15
C00003966 External link 512 Agecorynin D
/ 2-(2,4-Dihydroxy-5-methoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one
No. 8 No. 15
C00003934 External link 512 Hymenoxin
/ 5,7-Dihydroxy-6,8,3',4'-tetramethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6,8-dimethoxy-4H-1-benzopyran-4-one
CHEMBL504325
C068785
No. 8 No. 15
C00003883 External link 512 Gardenin B
/ Demethyltangeretin
/ 5-Hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL226512
7 / 10 / 4 No. 8 No. 15
C00002547 External link 512 (-)-Medicarpin
/ 3-Hydroxy-9-methoxypterocarpan
CHEMBL238845
CHEMBL413297
C047353
3 / 1 / 1 No. 66 No. 15
C00002546 External link 512 Inermin
/ Maackiain
/ (-)-Maackiain
/ Demethylpterocarpin
/ 3-Hydroxy-8,9-methylenedioxypterocarpan
CHEMBL334918
CHEMBL239047
CHEMBL445279
3 / 2 / 3 No. 66 No. 15
C00007929 External link 512 2',6'-Dihydroxy-4'-methoxydihydrochalcone
CHEMBL486009
No. 90 No. 13

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75496 Geminin Unclassified protein C00002547 C00003883 0 / 0
P15559 NAD(P)H dehydrogenase [quinone] 1 Enzyme C00001075 C00003883 0 / 0
P13866 Sodium/glucose cotransporter 1 Glucose C00002546 1 / 1
P31639 Sodium/glucose cotransporter 2 Glucose C00002546 1 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00003883 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003883 2 / 0
Q99700 Ataxin-2 Unclassified protein C00003883 1 / 1
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00003883 7 / 3
P28482 Mitogen-activated protein kinase 1 Erk C00003883 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002546 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002547 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002547 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
#606824 Glucose/galactose malabsorption; ggm P13866
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#233100 Renal glucosuria; glys1 P31639
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (8)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01261 Congenital glucose-galactose malabsorption (GGM) P13866 (related)
H01126 Familial renal glucosuria (FRG) P31639 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)