| Organism name | Ozothamnus lycopodioides | 
|---|---|
| Genus | Ozothamnus | 
| Family | Asteraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Ozothamnus lycopodioides | 
|---|---|
| Linked NCBI taxonomy ID | 1284896 | 
| Linked level | species | 
| Family in NCBI taxonomy | Asteraceae | 
|---|---|
| ID | 4210 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00004638   | Quercetin 3,7-dimethyl ether / 5,3',4'-Trihydroxy-3,7-dimethoxyflavone / 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one | CHEMBL164861 | C065497 | 2 / 1 / 2 | No. 3 | No. 15 |   | |
| C00004733   | 3,7,8-Trimethylgossypetin / Gossypetin 3,7,8-trimethyl ether / 5,3',4'-Trihydroxy-3,7,8-trimethoxyflavone / 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-1-benzopyran-4-one | CHEMBL349973 | No. 3 | No. 15 |   | |||
| C00004684   | Axillarin / Quercetagetin 3,6-dimethyl ether / 3,6-Dimethoxy-5,7,3',4'-tetrahydroxyflavone / 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3,6-dimethoxy-4H-1-benzopyran-4-one | CHEMBL487810 | C056669 | 1 / 1 / 1 | No. 3 | No. 15 |   | |
| C00001076   | Nobiletin / 3',4',5,6,7,8-Hexamethoxyflavone | CHEMBL76447 | C008661 | 22 / 23 / 20 | 5 / 2 | No. 8 | No. 15 |   | 
| C00004008   | Eupalestin / Conyzorigun / 5,6,7,8-Tetramethoxy-2-(7-methoxy-1,3-benzodioxol-5-yl)-4H-1-benzopyran-4-one | No. 8 | No. 15 |   | ||||
| C00004744   | Gossypetin 3,7,8,3',4'-pentamethyl ether / 5-Hydroxy-3,7,8,3',4'-pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-1-benzopyran-4-one | CHEMBL479326 | No. 8 | No. 15 |   | |||
| C00003977   | 5,6,7,8,3',4',5'-Heptamethoxyflavone | CHEMBL310982 | 1 / 1 / 0 | No. 8 | No. 15 |   | ||
| C00004005   | Linderoflavone B / Lucidin dimethyl ether / 5,6,7,8-Tetramethoxy-3',4'-(methylenedioxy)flavone / 2-(1,3-Benzodioxol-5-yl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one | CHEMBL483213 | No. 27 | No. 15 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00001076 C00004684 | 1 / 1 | 
| P08183 | Multidrug resistance protein 1 | drug | C00001076 C00003977 | 1 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001076 | 0 / 0 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001076 | 0 / 0 | 
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00004638 | 0 / 0 | 
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00001076 | 0 / 0 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001076 | 1 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001076 | 0 / 0 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001076 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00001076 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00001076 | 0 / 0 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001076 | 5 / 3 | 
| P00747 | Plasminogen | S1A | C00004638 | 1 / 2 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001076 | 3 / 3 | 
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001076 | 2 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001076 | 2 / 2 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001076 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001076 | 0 / 1 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001076 | 4 / 3 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001076 | 0 / 0 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001076 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00001076 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001076 | 1 / 2 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001076 | 1 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 972 | CD74, DHLAG, HLADG, II, Ia-GAMMA | CD74 molecule, major histocompatibility complex, class II invariant chain | C00001076 | 
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00001076 | 
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | C00001076 | 
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | C00001076 | 
| 4316 | MMP7, MMP-7, MPSL1, PUMP-1 | matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) | C00001076 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #614490 | Blood group, junior system; jr | Q9UNQ0 | 
| %606641 | Body mass index; bmi | P37231 | 
| #609338 | Carotid intimal medial thickness 1 | P37231 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #137800 | Glioma susceptibility 1; glm1 | P37231 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | P37231 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #160900 | Myotonic dystrophy 1; dm1 | Q9NR56 | 
| #601665 | Obesity | P37231 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #217090 | Plasminogen deficiency, type i | P00747 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 | Q9UNQ0 | 
| #278300 | Xanthinuria, type i | P47989 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00223 | Inherited thrombophilia | P00747
                            (related) | 
| H01206 | Plasminogen deficiency | P00747
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) Q13148 (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H00032 | Thyroid cancer | P37231
                            (related) | 
| H00409 | Type II diabetes mellitus | P37231
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P37231
                            (related) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) |