Species

KNApSAcK Entry

Organism name Isodon rubescens var. lushanensis
Genus Isodon
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Isodon
Linked NCBI taxonomy ID 204130
Linked level genus

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001078 External link 512 Lutexin
/ Orientin
/ Luteolin 8-C-beta-D-glucopyranoside
/ 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
CHEMBL520866
CHEMBL1468796
C065886
20 / 15 / 14 No. 22 No. 15
C00031075 External link 512 Ponicidin
CHEMBL401207
C090365
No. 83
C00031959 External link 512 Lasiodonin
No. 83
C00031121 External link 512 Rabdosin B
/ (+)-Rabdosin B
C037018
No. 241 No. 41
C00003443 External link 512 Isodonal
CHEMBL453800
No. 241 No. 41
C00031769 External link 512 Epinodosin
CHEMBL510160
CHEMBL1081333
No. 241 No. 41
C00031897 External link 512 Isodonoiol
/ Rabdosin C
/ Rabdophyllin G
CHEMBL452862
C037511
No. 241 No. 41
C00031989 External link 512 Lushanrubescensin H
/ (+)-Lushanrubescensin H
No. 241 No. 41
C00031761 External link 512 Enmenol
CHEMBL1080423
C038064
No. 339
C00031885 External link 512 Inflexusin
/ (-)-Inflexusin
No. 481
C00031988 External link 512 Lushanrubescensin G
/ (-)-Lushanrubescensin G
No. 735
C00031987 External link 512 Lushanrubescensin F
/ (-)-Lushanrubescensin F
No. 735
C00031990 External link 512 Lushanrubescensin I
/ (+)-Lushanrubescensin I
No. 3021

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001078 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001078 1 / 1
P06746 DNA polymerase beta Enzyme C00001078 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00001078 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001078 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00001078 3 / 1
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001078 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001078 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001078 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001078 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001078 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001078 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001078 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001078 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00001078 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001078 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001078 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001078 1 / 1
O00255 Menin Unclassified protein C00001078 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001078 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (14)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)