Species

KNApSAcK Entry

Organism name Rubus idaeus L.
Genus Rubus
Family Rosaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Rubus idaeus
Linked NCBI taxonomy ID 32247
Linked level species

Family

Family in NCBI taxonomy Rosaceae
ID 3745

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (20)

Species Activity
Rubus idaeus L. Anticancer
Rubus idaeus L. Anticholinesterase
Rubus idaeus L. Antiinflammatory
Rubus idaeus L. Antipyretic
Rubus idaeus L. Antiseptic
Rubus idaeus L. Antispasmodic
Rubus idaeus L. Antiviral
Rubus idaeus L. Astringent
Rubus idaeus L. Choleretic
Rubus idaeus L. Depurative
Rubus idaeus L. Diaphoretic
Rubus idaeus L. Diuretic
Rubus idaeus L. Hemostat
Rubus idaeus L. Laxative
Rubus idaeus L. Myostimulant
Rubus idaeus L. Postparturient
Rubus idaeus L. Stimulant
Rubus idaeus L. Tonic
Rubus idaeus L. Uterorelaxant
Rubus idaeus L. Uterotonic

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006672 External link 512 Cyanidin 3-(2G-glucosylrutinoside)
CHEMBL1171062
No. 5 No. 15
C00011153 External link 512 Gallogen
/ Ellagic acid
/ Elagostasine
/ Alizarin yellow
CHEMBL6246
D004610
104 / 97 / 100 77 / 9 No. 2068 No. 81
C00001179 External link 512 Vitamin C
/ L-Ascorbate
/ L-Ascorbic acid
/ (+)-Ascorbic acid
CHEMBL196
CHEMBL1161421
D001205
104 / 58 / 50 254 / 98 No. 8774

Human Protein / Gene in interactions

197 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P02545 Prelamin-A/C Unclassified protein C00001179 C00011153 11 / 10
P10636 Microtubule-associated protein tau Unclassified protein C00001179 C00011153 4 / 3
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001179 C00011153 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001179 C00011153 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00001179 C00011153 0 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00001179 C00011153 5 / 9
P49841 Glycogen synthase kinase-3 beta Gsk C00001179 C00011153 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00001179 C00011153 2 / 3
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00001179 C00011153 1 / 8
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001179 C00011153 0 / 1
P00918 Carbonic anhydrase 2 Lyase C00001179 C00011153 1 / 2
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00001179 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00001179 0 / 0
P06746 DNA polymerase beta Enzyme C00011153 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00001179 0 / 0
P04746 Pancreatic alpha-amylase Hydrolase C00001179 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00011153 1 / 1
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00011153 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00011153 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00011153 0 / 0
P29466 Caspase-1 C14 C00001179 0 / 0
P17252 Protein kinase C alpha type Alpha C00001179 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00001179 0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00011153 0 / 0
Q9UGH3 Solute carrier family 23 member 2 Ascorbate C00001179 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00001179 2 / 2
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00011153 0 / 0
Q8N1Q1 Carbonic anhydrase 13 Lyase C00011153 0 / 0
O14965 Aurora kinase A Aur C00011153 0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00011153 1 / 4
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00011153 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001179 1 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00011153 3 / 1
P68400 Casein kinase II subunit alpha Ck2 C00011153 0 / 0
P08246 Neutrophil elastase S1A C00001179 2 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00001179 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00001179 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00001179 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00001179 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00001179 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00001179 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00001179 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00001179 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00011153 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00001179 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00001179 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00001179 0 / 0
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily C00011153 1 / 3
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily C00011153 0 / 0
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family C00011153 1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein C00011153 1 / 8
Q9GZT9 Egl nine homolog 1 Enzyme C00001179 1 / 1
P54132 Bloom syndrome protein Enzyme C00011153 1 / 2
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00011153 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00011153 1 / 0
P13674 Prolyl 4-hydroxylase subunit alpha-1 Enzyme C00001179 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00001179 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001179 0 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00001179 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001179 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00001179 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00001179 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00001179 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00001179 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00011153 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00001179 0 / 0
Q96KS0 Egl nine homolog 2 Enzyme C00001179 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00001179 1 / 1
O15296 Arachidonate 15-lipoxygenase B Enzyme C00011153 0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00001179 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00001179 1 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00011153 0 / 0
P68871 Hemoglobin subunit beta Secreted protein C00011153 4 / 4
O43570 Carbonic anhydrase 12 Lyase C00011153 1 / 2
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00011153 1 / 1
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00001179 0 / 0
P54760 Ephrin type-B receptor 4 Eph C00011153 0 / 0
P39748 Flap endonuclease 1 Enzyme C00011153 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00011153 0 / 0
Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor Enzyme C00001179 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00011153 2 / 0
O75496 Geminin Unclassified protein C00011153 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00001179 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00001179 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00001179 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00001179 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00001179 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00001179 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00001179 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00001179 0 / 0
P15121 Aldose reductase Enzyme C00011153 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00001179 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00001179 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00001179 1 / 0
P00915 Carbonic anhydrase 1 Lyase C00011153 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001179 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00001179 0 / 0
P08311 Cathepsin G S1A C00001179 0 / 0
Q05397 Focal adhesion kinase 1 Fak C00011153 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00001179 1 / 0
P09211 Glutathione S-transferase P Enzyme C00011153 0 / 1
Q02763 Angiopoietin-1 receptor Tie C00011153 1 / 1
P03956 Interstitial collagenase M10A C00001179 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00001179 0 / 0
P15056 Serine/threonine-protein kinase B-raf Raf C00011153 6 / 3
P08107 Heat shock 70 kDa protein 1A/1B Unclassified protein C00011153 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00011153 1 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily C00011153 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00011153 1 / 2
Q4U2R8 Solute carrier family 22 member 6 Antiporter C00011153 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00011153 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00011153 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00011153 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00001179 0 / 1
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00011153 5 / 4
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00001179 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00001179 0 / 0
P14679 Tyrosinase Oxidoreductase C00001179 4 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00001179 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00001179 2 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00011153 2 / 0
P09619 Platelet-derived growth factor receptor beta Pdgfr C00011153 5 / 1
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00001179 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00001179 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00011153 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00001179 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00001179 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00001179 0 / 0
P04745 Alpha-amylase 1 Enzyme C00001179 0 / 0
Q96GD4 Aurora kinase B Aur C00011153 0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00011153 1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00011153 2 / 3
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00001179 1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00011153 0 / 0
P35916 Vascular endothelial growth factor receptor 3 Vegfr C00011153 2 / 1
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00001179 2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001179 0 / 0
P00390 Glutathione reductase, mitochondrial Oxidoreductase C00011153 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00011153 0 / 1
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 C00011153 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00011153 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00011153 2 / 2
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00001179 0 / 0
P03372 Estrogen receptor NR3A1 C00001179 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00001179 1 / 0
P12821 Angiotensin-converting enzyme M2 C00011153 4 / 2
P22303 Acetylcholinesterase Hydrolase C00001179 1 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00001179 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00001179 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00001179 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00001179 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00001179 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00001179 0 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00011153 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00001179 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00011153 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00011153 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00011153 4 / 1
Q9H6Z9 Egl nine homolog 3 Enzyme C00001179 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001179 0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00001179 0 / 0
P07949 Proto-oncogene tyrosine-protein kinase receptor Ret Ret C00011153 9 / 4
Q9UNA4 DNA polymerase iota Enzyme C00011153 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00011153 0 / 0
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00011153 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00011153 7 / 37
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001179 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00001179 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00001179 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00001179 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00001179 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00001179 1 / 1
P07451 Carbonic anhydrase 3 Lyase C00011153 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00001179 0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00001179 0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00011153 1 / 0
P22748 Carbonic anhydrase 4 Lyase C00011153 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00011153 0 / 0
P11142 Heat shock cognate 71 kDa protein Unclassified protein C00011153 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00011153 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00011153 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00011153 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00011153 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00011153 1 / 0
O00255 Menin Unclassified protein C00011153 2 / 5
Q13951 Core-binding factor subunit beta Unclassified protein C00011153 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00011153 1 / 4
Q9NSA0 Solute carrier family 22 member 11 Transporter C00011153 0 / 0
P20248 Cyclin-A2 Other cytosolic protein C00011153 0 / 0
P78396 Cyclin-A1 Other cytosolic protein C00011153 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00011153 0 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka C00011153 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00011153 0 / 0
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka C00011153 0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily C00011153 1 / 1
P06748 Nucleophosmin Other nuclear protein C00011153 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00011153 0 / 0

317 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00001179 C00011153
7453 WARS, GAMMA-2, IFI53, IFP53 tryptophanyl-tRNA synthetase (EC:6.1.1.2) C00001179 C00011153
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00001179 C00011153
6774 STAT3, APRF, HIES signal transducer and activator of transcription 3 (acute-phase response factor) C00001179 C00011153
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00001179 C00011153
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00001179 C00011153
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00001179 C00011153
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00001179 C00011153
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00001179 C00011153
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001179 C00011153
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00001179 C00011153
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00001179 C00011153
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00001179 C00011153
467 ATF3 activating transcription factor 3 C00001179 C00011153
2961 GTF2E2, FE, TF2E2, TFIIE-B general transcription factor IIE, polypeptide 2, beta 34kDa C00011153
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00001179
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00001179
397 ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 Rho GDP dissociation inhibitor (GDI) beta C00001179
16 AARS, CMT2N alanyl-tRNA synthetase (EC:6.1.1.7) C00001179
338 APOB, FLDB, LDLCQ4 apolipoprotein B C00001179
9212 AURKB, AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5, aurkb-sv1, aurkb-sv2 aurora kinase B (EC:2.7.11.1) C00001179
581 BAX, BCL2L4 BCL2-associated X protein C00001179
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00001179
335 APOA1 apolipoprotein A-I C00001179
79370 BCL2L14, BCLG BCL2-like 14 (apoptosis facilitator) C00001179
632 BGLAP, BGP, OC, OCN bone gamma-carboxyglutamate (gla) protein C00001179
12095 C00001179
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00001179
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00001179
699 BUB1, BUB1A, BUB1L, hBUB1 BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) C00001179
768 CA9, CAIX, MN carbonic anhydrase IX (EC:4.2.1.1) C00001179
301 ANXA1, ANX1, LPC1 annexin A1 C00001179
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00001179
847 CAT catalase (EC:1.11.1.6) C00001179
875 CBS, HIP4 cystathionine-beta-synthase (EC:4.2.1.22) C00001179
290 ANPEP, APN, CD13, GP150, LAP1, P150, PEPN alanyl (membrane) aminopeptidase (EC:3.4.11.2) C00001179
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00001179
894 CCND2, KIAK0002 cyclin D2 C00001179
100133941 CD24, CD24A CD24 molecule C00001179
947 CD34 CD34 molecule C00001179
958 CD40, Bp50, CDW40, TNFRSF5, p50 CD40 molecule, TNF receptor superfamily member 5 C00001179
990 CDC6, CDC18L, HsCDC18, HsCDC6 cell division cycle 6 C00001179
728642 CDK11A, CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA cyclin-dependent kinase 11A (EC:2.7.11.22) C00001179
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00001179
629 CFB, AHUS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2 complement factor B (EC:3.4.21.47) C00001179
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00001179
11113 CIT, CRIK, STK21 citron (rho-interacting, serine/threonine kinase 21) (EC:2.7.11.1) C00001179
1264 CNN1, SMCC, Sm-Calp calponin 1, basic, smooth muscle C00001179
1270 CNTF, HCNTF ciliary neurotrophic factor C00001179
1277 COL1A1, OI4 collagen, type I, alpha 1 C00001179
1380 CR2, C3DR, CD21, CR, CVID7, SLEB9 complement component (3d/Epstein Barr virus) receptor 2 C00001179
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00001179
1519 CTSO, CTSO1 cathepsin O (EC:3.4.22.42) C00001179
3627 CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 chemokine (C-X-C motif) ligand 10 C00001179
6372 CXCL6, CKA-3, GCP-2, GCP2, SCYB6 chemokine (C-X-C motif) ligand 6 C00001179
4283 CXCL9, CMK, Humig, MIG, SCYB9, crg-10 chemokine (C-X-C motif) ligand 9 C00001179
643 CXCR5, BLR1, CD185, MDR15 chemokine (C-X-C motif) receptor 5 C00001179
79901 CYBRD1, CYB561A2, DCYTB, FRRS3 cytochrome b reductase 1 C00001179
1583 CYP11A1, CYP11A, CYPXIA1, P450SCC cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6) C00001179
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001179
248 ALPI, IAP alkaline phosphatase, intestinal (EC:3.1.3.1) C00001179
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00001179
1556 CYP2B7P, CYP2B, CYP2B7, CYP2B7P1 cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene C00001179
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00001179
22943 DKK1, DKK-1, SK dickkopf WNT signaling pathway inhibitor 1 C00001179
9787 DLGAP5, DLG7, HURP discs, large (Drosophila) homolog-associated protein 5 C00001179
54431 DNAJC10, ERdj5, JPDI, MTHr, PDIA19 DnaJ (Hsp40) homolog, subfamily C, member 10 C00001179
1773 DNASE1, DNL1, DRNI deoxyribonuclease I (EC:3.1.21.1) C00001179
1803 DPP4, ADABP, ADCP2, CD26, DPPIV, TP103 dipeptidyl-peptidase 4 (EC:3.4.14.5) C00001179
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00001179
1908 EDN3, ET-3, ET3, HSCR4, PPET3, WS4B endothelin 3 C00001179
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00001179
112399 EGLN3, HIFP4H3, HIFPH3, PHD3 egl-9 family hypoxia-inducible factor 3 (EC:1.14.11.29) C00001179
8894 EIF2S2, EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa C00001179
8661 EIF3A, EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185 eukaryotic translation initiation factor 3, subunit A C00001179
8343525 C00001179
1973 EIF4A1, DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I eukaryotic translation initiation factor 4A1 (EC:3.6.4.13) C00001179
2012 EMP1, CL-20, EMP-1, TMP epithelial membrane protein 1 C00001179
2014 EMP3, YMP epithelial membrane protein 3 C00001179
2034 EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 endothelial PAS domain protein 1 C00001179
2052 EPHX1, EPHX, EPOX, HYL1, MEH epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9) C00001179
2053 EPHX2, CEH, SEH epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) C00001179
2058 EPRS, EARS, GLUPRORS, PARS, QARS, QPRS glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17) C00001179
2172 FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP fatty acid binding protein 6, ileal C00001179
2321 FLT1, FLT, FLT-1, VEGFR-1, VEGFR1 fms-related tyrosine kinase 1 (EC:2.7.10.1) C00001179
2326 FMO1 flavin containing monooxygenase 1 (EC:1.14.13.8) C00001179
2330 FMO5 flavin containing monooxygenase 5 (EC:1.14.13.8) C00001179
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00001179
2302 FOXJ1, FKHL13, HFH-4, HFH4 forkhead box J1 C00001179
2534 FYN, SLK, SYN, p59-FYN FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2) C00001179
2535 FZD2, Fz2, fz-2, fzE2, hFz2 frizzled family receptor 2 C00001179
50486 G0S2, RP1-28O10.2 G0/G1switch 2 C00001179
2580 GAK, DNAJ26, DNAJC26 cyclin G associated kinase (EC:2.7.11.1) C00001179
2617 GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1 glycyl-tRNA synthetase (EC:6.1.1.14) C00001179
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00001179
2674 GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1 GDNF family receptor alpha 1 C00001179
2744 GLS, AAD20, GAC, GAM, GLS1, KGA glutaminase (EC:3.5.1.2) C00001179
2876 GPX1, GPXD, GSHPX1 glutathione peroxidase 1 (EC:1.11.1.9) C00001179
2877 GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9) C00001179
2936 GSR glutathione reductase (EC:1.8.1.7) C00001179
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00001179
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00001179
2952 GSTT1 glutathione S-transferase theta 1 (EC:2.5.1.18) C00001179
2965 GTF2H1, BTF2, P62, TFB1, TFIIH general transcription factor IIH, polypeptide 1, 62kDa C00001179
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00001179
9843 HEPH, CPL hephaestin C00001179
9709 HERPUD1, HERP, Mif1, SUP homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 C00001179
231 AKR1B1, ADR, ALDR1, ALR2, AR aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) C00001179
3098 HK1, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1 hexokinase 1 (EC:2.7.1.1) C00001179
112 ADCY6, AC6 adenylate cyclase 6 (EC:4.6.1.1) C00001179
3240 HP, BP, HP2ALPHA2, HPA1S haptoglobin C00001179
3283 HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) C00001179
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00001179
3309 HSPA5, BIP, GRP78, MIF2 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) C00001179
3313 HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 heat shock 70kDa protein 9 (mortalin) C00001179
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00001179
3347 HTN3, HIS2, HTN2, HTN5 histatin 3 C00001179
3376 IARS, IARS1, ILERS, ILRS, IRS, PRO0785 isoleucyl-tRNA synthetase (EC:6.1.1.5) C00001179
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00001179
8870 IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1 immediate early response 3 C00001179
3488 IGFBP5, IBP5 insulin-like growth factor binding protein 5 C00001179
10320 IKZF1, Hs.54452, IK1, IKAROS, LYF1, PRO0758, ZNFN1A1, hIk-1 IKAROS family zinc finger 1 (Ikaros) C00001179
59 ACTA2, AAT6, ACTSA, MYMY5 actin, alpha 2, smooth muscle, aorta C00001179
59272 ACE2, ACEH angiotensin I converting enzyme 2 (EC:3.4.17.23) C00001179
3745 KCNB1, DRK1, KV2.1, h-DRK1 potassium voltage-gated channel, Shab-related subfamily, member 1 C00001179
3791 KDR, CD309, FLK1, VEGFR, VEGFR2 kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1) C00001179
9493 KIF23, CHO1, KNSL5, MKLP-1, MKLP1 kinesin family member 23 C00001179
3932 LCK, LSK, YT16, p56lck, pp58lck lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) C00001179
3956 LGALS1, GAL1, GBP lectin, galactoside-binding, soluble, 1 C00001179
4017 LOXL2, LOR2, WS9-14 lysyl oxidase-like 2 (EC:1.4.3.-) C00001179
4067 LYN, JTK8, p53Lyn, p56Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) C00001179
23764 MAFF, U-MAF, hMafF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F C00001179
10892 MALT1, IMD12, MLT, MLT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 (EC:3.4.22.-) C00001179
5606 MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2 mitogen-activated protein kinase kinase 3 (EC:2.7.12.2) C00001179
5608 MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3 mitogen-activated protein kinase kinase 6 (EC:2.7.12.2) C00001179
4217 MAP3K5, ASK1, MAPKKK5, MEKK5 mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25) C00001179
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00001179
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00001179
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00001179
4173 MCM4, CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21 minichromosome maintenance complex component 4 (EC:3.6.4.12) C00001179
4224 MEP1A, PPHA meprin A, alpha (PABA peptide hydrolase) (EC:3.4.24.18) C00001179
4233 MET, AUTS9, HGFR, RCCP2, c-Met met proto-oncogene (EC:2.7.10.1) C00001179
4288 MKI67, KIA, MIB-1 marker of proliferation Ki-67 C00001179
4292 MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1 mutL homolog 1 C00001179
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00001179
4316 MMP7, MMP-7, MPSL1, PUMP-1 matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) C00001179
4353 MPO myeloperoxidase (EC:1.11.2.2) C00001179
4436 MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2 mutS homolog 2 C00001179
4485 MST1, D3F15S2, DNF15S2, HGFL, MSP, NF15S2 macrophage stimulating 1 (hepatocyte growth factor-like) C00001179
11223 MST1L, BRF-1, D1F15S1A, MSPL-7, MSPL7, MST1P9, MSTP7, MSTP9 macrophage stimulating 1-like C00001179
4504 MT3, GIF, GIFB, GRIF, ZnMT3 metallothionein 3 C00001179
10797 MTHFD2, NMDMC methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15) C00001179
4605 MYBL2, B-MYB, BMYB v-myb avian myeloblastosis viral oncogene homolog-like 2 C00001179
4640 MYO1A, BBMI, DFNA48, MIHC, MYHL myosin IA C00001179
4677 NARS, ASNRS, NARS1 asparaginyl-tRNA synthetase (EC:6.1.1.22) C00001179
10397 NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5 N-myc downstream regulated 1 C00001179
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00001179
4800 NFYA, CBF-A, CBF-B, HAP2, NF-YA nuclear transcription factor Y, alpha C00001179
4814 NINJ1, NIN1, NINJURIN ninjurin 1 C00001179
7080 NKX2-1, BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1 NK2 homeobox 1 C00001179
4830 NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1 NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6) C00001179
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00001179
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00001179
2908 NR3C1, GCCR, GCR, GR, GRL nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) C00001179
8013 NR4A3, CHN, CSMF, MINOR, NOR1, TEC nuclear receptor subfamily 4, group A, member 3 C00001179
4973 OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 oxidized low density lipoprotein (lectin-like) receptor 1 C00001179
10956 OS9, ERLEC2, OS-9 osteosarcoma amplified 9, endoplasmic reticulum lectin C00001179
8974 P4HA2 prolyl 4-hydroxylase, alpha polypeptide II (EC:1.14.11.2) C00001179
54681 P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) C00001179
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001179
5106 PCK2, PEPCK, PEPCK-M, PEPCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32) C00001179
64714 PDIA2, PDA2, PDI, PDIP, PDIR protein disulfide isomerase family A, member 2 (EC:5.3.4.1) C00001179
2923 PDIA3, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC protein disulfide isomerase family A, member 3 (EC:5.3.4.1) C00001179
26227 PHGDH, 3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA phosphoglycerate dehydrogenase (EC:1.1.1.95) C00001179
22822 PHLDA1, DT1P1B11, PHRIP, TDAG51 pleckstrin homology-like domain, family A, member 1 C00001179
7262 PHLDA2, BRW1C, BWR1C, HLDA2, IPL, TSSC3 pleckstrin homology-like domain, family A, member 2 C00001179
11145 PLA2G16, AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3 phospholipase A2, group XVI (EC:3.1.1.4 3.1.1.32) C00001179
5340 PLG plasminogen (EC:3.4.21.7) C00001179
5347 PLK1, PLK, STPK13 polo-like kinase 1 (EC:2.7.11.21) C00001179
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00001179
5376 PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110 peripheral myelin protein 22 C00001179
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00001179
5445 PON2 paraoxonase 2 (EC:3.1.1.2 3.1.1.81) C00001179
5460 POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 POU class 5 homeobox 1 C00001179
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001179
5588 PRKCQ, PRKCT, nPKC-theta protein kinase C, theta (EC:2.7.11.13) C00001179
38175 C00001179
5702 PSMC3, TBP1 proteasome (prosome, macropain) 26S subunit, ATPase, 3 C00001179
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00001179
5865 RAB3B RAB3B, member RAS oncogene family C00001179
5870 RAB6A, RAB6 RAB6A, member RAS oncogene family C00001179
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00001179
5889 RAD51C, BROVCA3, FANCO, R51H3, RAD51L2 RAD51 paralog C C00001179
25788 RAD54B, RDH54 RAD54 homolog B (S. cerevisiae) C00001179
1827 RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1 regulator of calcineurin 1 C00001179
860 RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA runt-related transcription factor 2 C00001179
795 S100G, CABP, CABP1, CABP9K, CALB3 S100 calcium binding protein G C00001179
5055 SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 C00001179
83667 SESN2, HI95, SES2, SEST2 sestrin 2 C00001179
6439 SFTPB, PSP-B, SFTB3, SFTP3, SMDP1, SP-B surfactant protein B C00001179
6472 SHMT2, GLYA, SHMT serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1) C00001179
6476 SI sucrase-isomaltase (alpha-glucosidase) (EC:3.2.1.10 3.2.1.48) C00001179
4891 SLC11A2, DCT1, DMT1, NRAMP2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 C00001179
10864 SLC22A7, NLT, OAT2 solute carrier family 22 (organic anion transporter), member 7 C00001179
9963 SLC23A1, SLC23A2, SVCT1, YSPL3 solute carrier family 23 (ascorbic acid transporter), member 1 C00001179
9962 SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2 solute carrier family 23 (ascorbic acid transporter), member 2 C00001179
79677 SMC6, SMC-6, SMC6L1, hSMC6 structural maintenance of chromosomes 6 C00001179
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00001179
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00001179
6657 SOX2, ANOP3, MCOPS3 SRY (sex determining region Y)-box 2 C00001179
6667 SP1 Sp1 transcription factor C00001179
6670 SP3, SPR2 Sp3 transcription factor C00001179
6671 SP4, HF1B, SPR-1 Sp4 transcription factor C00001179
6678 SPARC, ON secreted protein, acidic, cysteine-rich (osteonectin) C00001179
6696 SPP1, BNSP, BSPI, ETA-1, OPN secreted phosphoprotein 1 C00001179
6772 STAT1, CANDF7, ISGF-3, STAT91 signal transducer and activator of transcription 1, 91kDa C00001179
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001179
9262 STK17B, DRAK2 serine/threonine kinase 17b (EC:2.7.11.1) C00001179
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00001179
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00001179
20888 C00001179
6822 SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14) C00001179
6876 TAGLN, SM22, SMCC, TAGLN1, WS3-10 transgelin C00001179
6897 TARS, ThrRS threonyl-tRNA synthetase (EC:6.1.1.3) C00001179
6901 TAZ, BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1 tafazzin C00001179
7018 TF, PRO1557, PRO2086, TFQTL1 transferrin C00001179
7032 TFF2, SML1, SP trefoil factor 2 C00001179
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00001179
7076 TIMP1, CLGI, EPA, EPO, HCI, TIMP TIMP metallopeptidase inhibitor 1 C00001179
4071 TM4SF1, H-L6, L6, M3S1, TAAL6 transmembrane 4 L six family member 1 C00001179
164656 TMPRSS6, IRIDA transmembrane protease, serine 6 C00001179
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00001179
4982 TNFRSF11B, OCIF, OPG, TR1 tumor necrosis factor receptor superfamily, member 11b C00001179
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00001179
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001179
11257 TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1 TP53 target 1 (non-protein coding) C00001179
57761 TRIB3, C20orf97, NIPK, SINK, SKIP3, TRB3 tribbles pseudokinase 3 C00001179
9322 TRIP10, CIP4, HSTP, STOT, STP thyroid hormone receptor interactor 10 C00001179
7224 TRPC5, TRP5 transient receptor potential cation channel, subfamily C, member 5 C00001179
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00001179
7319 UBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2 ubiquitin-conjugating enzyme E2A (EC:6.3.2.19) C00001179
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00001179
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00001179
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00001179
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00001179
7428 VHL, HRCA1, RCA1, VHL1, pVHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase C00001179
55350 VNN3, HSA238982 vanin 3 C00001179
7443 VRK1, PCH1, PCH1A vaccinia related kinase 1 (EC:2.7.11.1) C00001179
19 ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD ATP-binding cassette, sub-family A (ABC1), member 1 C00001179
10352 WARS2, TrpRS tryptophanyl tRNA synthetase 2, mitochondrial (EC:6.1.1.2) C00001179
25937 WWTR1, TAZ WW domain containing transcription regulator 1 C00001179
7512 XPNPEP2, APP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (EC:3.4.11.9) C00001179
7515 XRCC1, RCC X-ray repair complementing defective repair in Chinese hamster cells 1 C00001179
7718 ZNF165, CT53, LD65, ZSCAN7 zinc finger protein 165 C00001179
55 ACPP, 5'-NT, ACP-3, ACP3, PAP acid phosphatase, prostate (EC:3.1.3.2 3.1.3.5) C00011153
213 ALB, PRO0883, PRO0903, PRO1341 albumin C00011153
317 APAF1, APAF-1, CED4 apoptotic peptidase activating factor 1 C00011153
429 ASCL1, ASH1, HASH1, MASH1, bHLHa46 achaete-scute family bHLH transcription factor 1 C00011153
9474 ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5 autophagy related 5 C00011153
654 BMP6, VGR, VGR1 bone morphogenetic protein 6 C00011153
2972 BRF1, BRF, BRF-1, GTF3B, TAF3B2, TAF3C, TAFIII90, TF3B90, TFIIIB90, hBRF BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit C00011153
811 CALR, CRT, RO, SSA, cC1qR calreticulin C00011153
929 CD14 CD14 molecule C00011153
1616 DAXX, BING2, DAP6, EAP1 death-domain associated protein C00011153
1676 DFFA, DFF-45, DFF1, ICAD DNA fragmentation factor, 45kDa, alpha polypeptide C00011153
1877 E4F1, E4F E4F transcription factor 1 C00011153
1960 EGR3, EGR-3, PILOT early growth response 3 C00011153
2033 EP300, KAT3B, RSTS2, p300 E1A binding protein p300 (EC:2.3.1.48) C00011153
2060 EPS15, AF-1P, AF1P, MLLT5 epidermal growth factor receptor pathway substrate 15 C00011153
2145 EZH1, KMT6B enhancer of zeste homolog 1 (Drosophila) (EC:2.1.1.43) C00011153
2161 F12, HAE3, HAEX, HAF coagulation factor XII (Hageman factor) (EC:3.4.21.38) C00011153
2260 FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 fibroblast growth factor receptor 1 (EC:2.7.10.1) C00011153
2316 FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD filamin A, alpha C00011153
2822 GPLD1, GPIPLD, GPIPLDM, PIGPLD, PIGPLD1 glycosylphosphatidylinositol specific phospholipase D1 (EC:3.1.4.50) C00011153
2941 GSTA4, GSTA4-4, GTA4 glutathione S-transferase alpha 4 (EC:2.5.1.18) C00011153
55937 APOM, G3a, HSPC336, NG20, apo-M apolipoprotein M C00001179
2968 GTF2H4, P52, TFB2, TFIIH general transcription factor IIH, polypeptide 4, 52kDa C00011153
9592 IER2, ETR101 immediate early response 2 C00011153
3485 IGFBP2, IBP2, IGF-BP53 insulin-like growth factor binding protein 2, 36kDa C00011153
3487 IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4 insulin-like growth factor binding protein 4 C00011153
3554 IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80 interleukin 1 receptor, type I C00011153
3635 INPP5D, SHIP, SHIP-1, SHIP1, SIP-145, hp51CN inositol polyphosphate-5-phosphatase, 145kDa (EC:3.1.3.86) C00011153
10788 IQGAP2 IQ motif containing GTPase activating protein 2 C00011153
10379 IRF9, IRF-9, ISGF3, ISGF3G, p48 interferon regulatory factor 9 C00011153
354 KLK3, APS, KLK2A1, PSA, hK3 kallikrein-related peptidase 3 (EC:3.4.21.77) C00011153
9516 LITAF, PIG7, SIMPLE, TP53I7 lipopolysaccharide-induced TNF factor C00011153
4130 MAP1A, MAP1L, MTAP1A microtubule-associated protein 1A C00011153
23531 MMD, MMA, MMD1, PAQR11 monocyte to macrophage differentiation-associated C00011153
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00011153
4791 NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) C00011153
4826 NNAT, Peg5 neuronatin C00011153
10528 NOP56, NOL5A, SCA36 NOP56 ribonucleoprotein C00011153
4862 NPAS2, MOP4, PASD4, bHLHe9 neuronal PAS domain protein 2 C00011153
9970 NR1I3, CAR, CAR1, MB67 nuclear receptor subfamily 1, group I, member 3 C00011153
8505 PARG, PARG99 poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) C00011153
5320 PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) C00011153
5355 PLP2, A4, A4LSB proteolipid protein 2 (colonic epithelium-enriched) C00011153
5371 PML, MYL, PP8675, RNF71, TRIM19 promyelocytic leukemia C00011153
5467 PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB peroxisome proliferator-activated receptor delta C00011153
5592 PRKG1, 1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha protein kinase, cGMP-dependent, type I (EC:2.7.11.12) C00011153
5764 PTN, HARP, HBGF8, HBNF, NEGF1 pleiotrophin C00011153
5799 PTPRN2, IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2 protein tyrosine phosphatase, receptor type, N polypeptide 2 (EC:3.1.3.48) C00011153
5901 RAN, ARA24, Gsp1, TC4 RAN, member RAS oncogene family C00011153
8434 RECK, ST15 reversion-inducing-cysteine-rich protein with kazal motifs C00011153
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00011153
8490 RGS5, MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129 regulator of G-protein signaling 5 C00011153
6319 SCD, FADS5, MSTP008, SCD1, SCDOS stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) C00011153
4735 SEPT2, DIFF6, NEDD-5, NEDD5, Pnutl3, hNedd5 septin 2 C00011153
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC:1.15.1.1) C00011153
9013 TAF1C, MGC:39976, SL1, TAFI110, TAFI95 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa C00011153
6938 TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20 transcription factor 12 C00011153
7015 TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT telomerase reverse transcriptase (EC:2.7.7.49) C00011153
7019 TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 transcription factor A, mitochondrial C00011153
7360 UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379 UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9) C00011153
7375 USP4, UNP, Unph ubiquitin specific peptidase 4 (proto-oncogene) (EC:3.4.19.12) C00011153
7704 ZBTB16, PLZF, ZNF145 zinc finger and BTB domain containing 16 C00011153
7750 ZMYM2, FIM, MYM, RAMP, SCLL, ZNF198 zinc finger, MYM-type 2 C00011153

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (131)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#208900 Ataxia-telangiectasia; at Q13315
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#114480 Breast cancer P31749
#300615 Brunner syndrome P21397
#115150 Cardiofaciocutaneous syndrome 1; cfc1 P15056
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#209880 Central hypoventilation syndrome, congenital; cchs P07949
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P07949
P15056
P31749
P84022
#615109 Cowden syndrome 6; cws6 P31749
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#119900 Digital clubbing, isolated congenital P15428
#246200 Donohue syndrome P06213
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 O75874
P04626
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#602089 Hemangioma, capillary infantile P35916
P35968
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#114550 Hepatocellular carcinoma P08581
#142623 Hirschsprung disease, susceptibility to, 1; hscr1 P07949
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#143860 Hyperchlorhidrosis, isolated O43570
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#270450 Insulin-like growth factor i, resistance to P08069
#603932 Intervertebral disc disease; idd P14780
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#613707 Leopard syndrome 3 P15056
#601626 Leukemia, acute myeloid; aml P09619
P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
P15056
#153100 Lymphedema, hereditary, ia P35916
#605027 Lymphoma, non-hodgkin, familial P15056
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#171400 Multiple endocrine neoplasia, type iia; men2a P07949
#162300 Multiple endocrine neoplasia, type iib; men2b P07949
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#254500 Myeloma, multiple P24385
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#159900 Myoclonic dystonia P14416
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#613706 Noonan syndrome 7; ns7 P15056
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#171300 Pheochromocytoma P07949
#172700 Pick disease of brain P10636
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#176920 Proteus syndrome P31749
#191830 Renal adysplasia P07949
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#267430 Renal tubular dysgenesis; rtd P12821
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#603903 Sickle cell anemia P68871
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P12821
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#155240 Thyroid carcinoma, familial medullary; mtc P07949
#188550 Thyroid carcinoma, papillary P07949
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (113)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
P08581 (related)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P24385 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
P08581 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
P68871 (marker)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P09619 (related)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P24385 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P08581 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
Q13315 (related)
H00006 Hairy-cell leukemia P04637 (related)
P24385 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
P24385 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
Q9UM73 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
P08069 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P68871 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P07949 (related)
P07949 (marker)
P15056 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P11802 (related)
P14679 (marker)
P15056 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
P24385 (marker)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00822 Renal agenesis and Renal adysplasia P07949 (related)
H00910 Hirschsprung disease (HD) P07949 (related)
H00916 Congenital central hypoventilation syndrome (CCHS) P07949 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00024 Prostate cancer P09211 (related)
P09211 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00523 Noonan syndrome and related disorders P15056 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00535 Lymphedemas P35916 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00094 DNA repair defects P54132 (related)
Q13315 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00531 Venous malformations Q02763 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

104 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002471 Cell Transformation, Neoplastic C00001179
C00011153
D009203 Myocardial Infarction C00001179
C00011153
D006965 Hyperplasia C00001179
C00011153
D011230 Precancerous Conditions C00001179
D018798 Anemia, Iron-Deficiency C00001179
D000749 Anemia, Megaloblastic C00001179
D000756 Anemia, Sideroblastic C00001179
D001206 Ascorbic Acid Deficiency C00001179
D001424 Bacterial Infections C00001179
D001766 Blindness C00001179
D001847 Bone Diseases C00001179
D001927 Brain Diseases C00001179
D002545 Brain Ischemia C00001179
D001943 Breast Neoplasms C00001179
D002277 Carcinoma C00001179
D006528 Carcinoma, Hepatocellular C00001179
D009202 Cardiomyopathies C00001179
D018376 Cardiovascular Abnormalities C00001179
D002318 Cardiovascular Diseases C00001179
D002375 Catalepsy C00001179
D002386 Cataract C00001179
D058186 Acute Kidney Injury C00001179
D002607 Charcot-Marie-Tooth Disease C00001179
D002869 Chromosome Aberrations C00001179
D003139 Common Cold C00001179
D020918 Complex Regional Pain Syndromes C00001179
D003327 Coronary Disease C00001179
D003681 Dehydration C00001179
D003924 Diabetes Mellitus, Type 2 C00001179
D003928 Diabetic Nephropathies C00001179
D003930 Diabetic Retinopathy C00001179
D056486 Drug-Induced Liver Injury C00001179
D062787 Drug Overdose C00001179
D064420 Drug-Related Side Effects and Adverse Reactions C00001179
C538011 Eales disease C00001179
D004890 Erythema C00001179
D005221 Fatigue C00001179
D006029 Glycosuria C00001179
D006130 Growth Disorders C00001179
D006212 Hallucinations C00001179
D006330 Heart Defects, Congenital C00001179
D006548 Hernia, Diaphragmatic C00001179
D015658 HIV Infections C00001179
D006959 Hyperoxaluria C00001179
D000647 Amnesia C00001179
D006973 Hypertension C00001179
D006977 Hypertension, Renal C00001179
D007022 Hypotension C00001179
D007037 Hypothyroidism C00001179
146850 IMMUNE SUPPRESSION C00001179
D007674 Kidney Diseases C00001179
D007683 Kidney Tubular Necrosis, Acute C00001179
D007859 Learning Disorders C00001179
D007945 Leukemia, Lymphoid C00001179
D008103 Liver Cirrhosis C00001179
D008114 Liver Neoplasms, Experimental C00001179
D008171 Lung Diseases C00001179
D008175 Lung Neoplasms C00001179
D020149 Manganese Poisoning C00001179
D008630 Mercury Poisoning C00001179
D048629 Micronuclei, Chromosome-Defective C00001179
D009120 Muscle Cramp C00001179
D009135 Muscular Diseases C00001179
D055371 Acute Lung Injury C00001179
D009325 Nausea C00001179
D009336 Necrosis C00001179
D009369 Neoplasms C00001179
D009374 Neoplasms, Experimental C00001179
D009395 Nephritis, Interstitial C00001179
D053040 Nephrolithiasis C00001179
D009410 Nerve Degeneration C00001179
D009422 Nervous System Diseases C00001179
D009765 Obesity C00001179
D009845 Oligospermia C00001179
D010149 Pain, Postoperative C00001179
D010212 Papilloma C00001179
D016491 Peripheral Vascular Diseases C00001179
D011041 Poisoning C00001179
D000740 Anemia C00001179
D011471 Prostatic Neoplasms C00001179
D011507 Proteinuria C00001179
D011561 Pseudoxanthoma Elasticum C00001179
D011605 Psychoses, Substance-Induced C00001179
D011654 Pulmonary Edema C00001179
D011657 Pulmonary Eosinophilia C00001179
D011658 Pulmonary Fibrosis C00001179
D051437 Renal Insufficiency C00001179
D012174 Retinitis Pigmentosa C00001179
D012614 Scurvy C00001179
D012640 Seizures C00001179
D012871 Skin Diseases C00001179
D013226 Status Epilepticus C00001179
D013274 Stomach Neoplasms C00001179
D013276 Stomach Ulcer C00001179
D020521 Stroke C00001179
D013375 Substance Withdrawal Syndrome C00001179
D013921 Thrombocytopenia C00001179
D001749 Urinary Bladder Neoplasms C00001179
D000014 Abnormalities, Drug-Induced C00011153
D007248 Infertility, Male C00011153
D015427 Reperfusion Injury C00011153
D012878 Skin Neoplasms C00011153
D013471 Sunburn C00011153
D013733 Testicular Diseases C00011153