Species

KNApSAcK Entry

Organism name Bauhinia purpurea
Genus Bauhinia
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Bauhinia purpurea
Linked NCBI taxonomy ID 3806
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00013600 External link 512 5,6-Dihydroxy-7-methoxyflavone 6-O-beta-D-xylopyranoside
/ 5-Hydroxy-7-methoxy-2-phenyl-6-(b-D-xylopyranosyloxy)-4H-1-benzopyran-4-one
No. 2 No. 15
C00008168 External link 512 Desmethoxymatteucinol
CHEMBL53439
5 / 1 / 4 No. 25 No. 14
C00007182 External link 512 3,4-Dihydroxychalcone 4-beta-L-arabinopyranosyl-(1->4)-galactoside
No. 169 No. 13
C00007220 External link 512 Butein 4'-arabinosyl-(1->4)-galactoside
No. 169 No. 13
C00014400 External link 512 6-(3''-Oxobutyl)taxifolin
/ 3,5,7,3',4'-Pentahydroxy-6-(3-oxobutyl)flavanone
No. 1881 No. 14
C00001200 External link 512 Pyruvic acid
CHEMBL1162144
D019289
5 / 2 / 2 10 / 4 No. 2782
C00041373 External link 512 Bauhiniastatin 4
CHEMBL480649
No. 3067
C00041371 External link 512 Bauhiniastatin 2
CHEMBL482245
No. 3067
C00041372 External link 512 Bauhiniastatin 3
CHEMBL510988
No. 3067
C00041370 External link 512 Bauhiniastatin 1
CHEMBL520775
No. 7693

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00008168 1 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00008168 0 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00008168 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00008168 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00008168 0 / 0
O15427 Monocarboxylate transporter 4 Unclassified protein C00001200 0 / 0
Q92959 Solute carrier organic anion transporter family member 2A1 Unclassified protein C00001200 1 / 0
O60669 Monocarboxylate transporter 2 Unclassified protein C00001200 0 / 0
Q05BR4 SLC16A10 protein Unclassified protein C00001200 0 / 0
Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO Unclassified protein C00001200 1 / 2

10 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
31 ACACA, ACAC, ACACAD, ACC, ACC1, ACCA acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14) C00001200
1487 CTBP1, BARS C-terminal binding protein 1 C00001200
1488 CTBP2 C-terminal binding protein 2 C00001200
1586 CYP17A1, CPT7, CYP17, P450C17, S17AH cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) C00001200
14103 C00001200
2516 NR5A1, AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3 nuclear receptor subfamily 5, group A, member 1 C00001200
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001200
23411 SIRT1, SIR2L1 sirtuin 1 C00001200
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00001200
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00001200

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#612938 Growth retardation, developmental delay, coarse facies, and early death; gdfd Q9C0B1
#614441 Hypertrophic osteoarthropathy, primary, autosomal recessive, 2; phoar2 Q92959
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (6)

KEGG name UniProt
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00409 Type II diabetes mellitus Q9C0B1 (related)
H00926 Growth retardation, developmental delay, coarse facies, and early death Q9C0B1 (related)

Diseases related to CTD interactions

4 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006943 Hyperglycemia C00001200
D028361 Mitochondrial Diseases C00001200
D009135 Muscular Diseases C00001200
D009336 Necrosis C00001200