Laurencia aldingensis

• Index
• Plant Species
• Metabolite list (2)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Laurencia aldingensis
Genus
Family
Kingdom

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Laurencia aldingensis
Linked NCBI taxonomy ID	1167835
Linked level	species

Family

Family in NCBI taxonomy	Rhodomelaceae
ID	2803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Eukaryota
ID	2759

Plant class

Plant class
ID

Metabolite list (2)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003648	Cholesterol / Cholesterin / Cholest-5-en-3beta-ol	CHEMBL112570 CHEMBL1597825 CHEMBL1867358	D002784	20 / 28 / 24	45 / 23	No. 53	No. 11
C00001233	Palmitic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 184	No. 68

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04150	Glucocorticoid receptor	NR3C1	C00001233 C00003648	0 / 1
P10275	Androgen receptor	NR3C4	C00001233 C00003648	3 / 4
P08183	Multidrug resistance protein 1	drug	C00001233 C00003648	1 / 0
O60603	Toll-like receptor 2	Membrane receptor	C00001233	1 / 1
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00001233	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003648	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003648	11 / 10
P08047	Transcription factor Sp1	Unclassified protein	C00001233	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00003648	4 / 2
Q16850	Lanosterol 14-alpha demethylase	Cytochrome P450 51A1	C00003648	0 / 0
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00001233	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00001233	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00003648	2 / 3
O75496	Geminin	Unclassified protein	C00001233	0 / 0
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00001233	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001233	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00003648	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001233	2 / 2
Q96RI1	Bile acid receptor	NR1H4	C00001233	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003648	0 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00001233	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00003648	2 / 0
P03372	Estrogen receptor	NR3A1	C00001233	1 / 1
P09884	DNA polymerase alpha catalytic subunit	Transferase	C00003648	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003648	0 / 0
O00204	Sulfotransferase family cytosolic 2B member 1	Enzyme	C00003648	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001233	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00003648	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003648	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00003648	0 / 0
Q9NY46	Sodium channel protein type 3 subunit alpha	SCN alpha, NaV1.x	C00003648	0 / 0
Q99250	Sodium channel protein type 2 subunit alpha	SCN alpha, NaV1.x	C00003648	2 / 2
P35498	Sodium channel protein type 1 subunit alpha	SCN alpha, NaV1.x	C00003648	3 / 2

77 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00001233 C00003648
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001233 C00003648
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00001233 C00003648
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001233
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00003648
64240	ABCG5, STSL	ATP-binding cassette, sub-family G (WHITE), member 5	C00003648
335	APOA1	apolipoprotein A-I	C00003648
857	CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV	caveolin 1, caveolae protein, 22kDa	C00003648
859	CAV3, LGMD1C, LQT9, VIP-21, VIP21	caveolin 3	C00003648
1050	CEBPA, C/EBP-alpha, CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	C00003648
1066	CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1	carboxylesterase 1 (EC:3.1.1.1 3.1.1.56)	C00003648
1583	CYP11A1, CYP11A, CYPXIA1, P450SCC	cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6)	C00003648
1593	CYP27A1, CP27, CTX, CYP27	cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15)	C00003648
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00003648
10858	CYP46A1, CP46, CYP46	cytochrome P450, family 46, subfamily A, polypeptide 1 (EC:1.14.13.98)	C00003648
1581	CYP7A1, CP7A, CYP7, CYPVII	cytochrome P450, family 7, subfamily A, polypeptide 1 (EC:1.14.13.17)	C00003648
1718	DHCR24, DCE, Nbla03646, SELADIN1, seladin-1	24-dehydrocholesterol reductase (EC:1.3.1.72)	C00003648
1717	DHCR7, SLOS	7-dehydrocholesterol reductase (EC:1.3.1.21)	C00003648
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00003648
2222	FDFT1, DGPT, ERG9, SQS, SS	farnesyl-diphosphate farnesyltransferase 1 (EC:2.5.1.21)	C00003648
2252	FGF7, HBGF-7, KGF	fibroblast growth factor 7	C00003648
2264	FGFR4, CD334, JTK2, TKF	fibroblast growth factor receptor 4 (EC:2.7.10.1)	C00003648
2773	GNAI3, 87U6, ARCND1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	C00003648
2778	GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PHP1A, PHP1B, PHP1C, POH	GNAS complex locus	C00003648
338442	HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g	hydroxycarboxylic acid receptor 2	C00003648
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003648
3667	IRS1, HIRS-1	insulin receptor substrate 1	C00003648
3931	LCAT	lecithin-cholesterol acyltransferase (EC:2.3.1.43)	C00003648
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00003648
4481	MSR1, CD204, SCARA1, SR-A, SRA, phSR1, phSR2	macrophage scavenger receptor 1	C00003648
4864	NPC1, NPC	Niemann-Pick disease, type C1	C00003648
7376	NR1H2, LXR-b, LXRB, NER, NER-I, RIP15, UNR	nuclear receptor subfamily 1, group H, member 2	C00003648
10062	NR1H3, LXR-a, LXRA, RLD-1	nuclear receptor subfamily 1, group H, member 3	C00003648
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00003648
5338	PLD2	phospholipase D2 (EC:3.1.4.4)	C00003648
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00003648
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00003648
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00003648
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00003648
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00003648
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00003648
6721	SREBF2, SREBP-2, SREBP2, bHLHd2	sterol regulatory element binding transcription factor 2	C00003648
6770	STAR, STARD1	steroidogenic acute regulatory protein	C00003648
27346	TMEM97, MAC30	transmembrane protein 97	C00003648
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00003648
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00001233
581	BAX, BCL2L4	BCL2-associated X protein	C00001233
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001233
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001233
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00001233
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00001233
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00001233
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00001233
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00001233
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00001233
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00001233
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00001233
64241	ABCG8, GBD4, STSL	ATP-binding cassette, sub-family G (WHITE), member 8	C00003648
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001233
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00001233
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001233
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00001233
4493	MT1E, MT1, MTD	metallothionein 1E	C00001233
4494	MT1F, MT1	metallothionein 1F	C00001233
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00001233
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00001233
4502	MT2A, MT2	metallothionein 2A	C00001233
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001233
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00001233
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001233
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00001233
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001233
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00001233
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001233
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00001233
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001233
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00001233

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions