Piptadenia macrocarpa

• Index
• Plant Species
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Piptadenia macrocarpa
Genus	Piptadenia
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Piptadenia
Linked NCBI taxonomy ID	148717
Linked level	genus

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00019220	Lupenone	CHEMBL486393 CHEMBL575188		3 / 4 / 2		No. 23	No. 51
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00008827	Mesquitol	CHEMBL96523		1 / 1 / 1		No. 52	No. 14
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00002519	Dalbergin / 6-Hydroxy-7-methoxy-4-phenylcoumarin	CHEMBL1829658				No. 54	No. 17
C00010198	Kuhlmannin / 6-Hydroxy-7,8-dimethoxy-4-phenylcoumarin	CHEMBL1568181		2 / 0 / 1		No. 54	No. 17
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00033681	beta-Sitosterol palmitate					No. 1152
C00001402	Bufotenine	CHEMBL416526	D002027	6 / 3 / 0		No. 1385	No. 4

Human Protein / Gene in interactions

29 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00003749 C00019308	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003672 C00019308	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003672 C00010198	0 / 1
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672 C00019308	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00003672 C00019220	4 / 2
P00734	Prothrombin	S1A	C00003672 C00019308	4 / 2
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00019308	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003672	1 / 0
P08183	Multidrug resistance protein 1	drug	C00003672	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003672	0 / 1
P11387	DNA topoisomerase 1	Isomerase	C00003749	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00010198	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00008827	1 / 1
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00019220	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001402	2 / 0
Q96RI1	Bile acid receptor	NR1H4	C00019220	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003672	0 / 0
P03372	Estrogen receptor	NR3A1	C00003672	1 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001402	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001402	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003672	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672	2 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00001402	1 / 0
P28221	5-hydroxytryptamine receptor 1D	Serotonin receptor	C00001402	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003672	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001402	0 / 0

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions