Ephedra helvetica

• Index
• Plant Species
• Metabolite list (2)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Ephedra helvetica
Genus	Ephedra
Family	Ephedraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Ephedra
Linked NCBI taxonomy ID	3387
Linked level	genus

Family

Family in NCBI taxonomy	Ephedraceae
ID	3386

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Spermatophyta
ID	58024

Metabolite list (2)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001409	Ephedrine / L-Ephedrine / 1(R),2(S)-erythro-(-)-Ephedrine	CHEMBL357080 CHEMBL211456 CHEMBL1590 CHEMBL1620154 CHEMBL2110656 CHEMBL2110905	D004809	13 / 12 / 10	7 / 50	No. 2149	No. 9
C00032016	Methylephedrine / N-Methylephedrine / (-)-Methylephedrine	CHEMBL445001 CHEMBL1589978		3 / 0 / 0		No. 2149	No. 9

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001409	1 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00001409	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00001409	3 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001409	0 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001409	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00032016	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00001409	1 / 1
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00001409	2 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001409	3 / 3
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00001409	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00001409	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001409	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001409	0 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00032016	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00001409	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00032016	0 / 0

7 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
335	APOA1	apolipoprotein A-I	C00001409
336	APOA2, Apo-AII, ApoA-II, apoAII	apolipoprotein A-II	C00001409
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00001409
341	APOC1	apolipoprotein C-I	C00001409
344	APOC2, APO-CII, APOC-II	apolipoprotein C-II	C00001409
345	APOC3, APOCIII, HALP2	apolipoprotein C-III	C00001409
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00001409

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions