Species

KNApSAcK Entry

Organism name Capsicum frutescens
Genus Capsicum
Family Solanaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Capsicum frutescens
Linked NCBI taxonomy ID 4073
Linked level species

Family

Family in NCBI taxonomy Solanaceae
ID 4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (59)

Species Activity
Capsicum frutescens L. spp. Analgesic
Capsicum frutescens L. spp. Anesthetic
Capsicum frutescens L. spp. Antiaggregant
Capsicum frutescens L. spp. Antibacterial
Capsicum frutescens L. spp. Anticancer
Capsicum frutescens L. spp. Antidote
Capsicum frutescens L. spp. Antiinflammatory
Capsicum frutescens L. spp. Antiischemic
Capsicum frutescens L. spp. Antinitrosaminic
Capsicum frutescens L. spp. Antioxidant
Capsicum frutescens L. spp. Antipsoriatic
Capsicum frutescens L. spp. Antipyretic
Capsicum frutescens L. spp. Antiseptic
Capsicum frutescens L. spp. Antispasmodic
Capsicum frutescens L. spp. Antiulcer
Capsicum frutescens L. spp. Antiviral
Capsicum frutescens L. spp. Aperitif
Capsicum frutescens L. spp. Astringent
Capsicum frutescens L. spp. Bradycardic
Capsicum frutescens L. spp. Bronchoconstrictor
Capsicum frutescens L. spp. Bronchodilator
Capsicum frutescens L. spp. Calcium Antagonist
Capsicum frutescens L. spp. Carcinogenic
Capsicum frutescens L. spp. Carminative
Capsicum frutescens L. spp. Catabolic
Capsicum frutescens L. spp. Choleretic
Capsicum frutescens L. spp. Circulostimulant
Capsicum frutescens L. spp. Corticosteronigenic
Capsicum frutescens L. spp. Couterirritant
Capsicum frutescens L. spp. Dart Poison
Capsicum frutescens L. spp. Decongestant
Capsicum frutescens L. spp. Diaphoretic
Capsicum frutescens L. spp. Digestive
Capsicum frutescens L. spp. Diuretic
Capsicum frutescens L. spp. Fibrinolytic
Capsicum frutescens L. spp. Gastrogogue
Capsicum frutescens L. spp. Hemolytic
Capsicum frutescens L. spp. Hemostat
Capsicum frutescens L. spp. Hyperemic
Capsicum frutescens L. spp. Hypocholesterolemic
Capsicum frutescens L. spp. Hypoglycemic
Capsicum frutescens L. spp. Hypotriglyceridemic
Capsicum frutescens L. spp. Insecticide
Capsicum frutescens L. spp. Irritant
Capsicum frutescens L. spp. Lipolytic
Capsicum frutescens L. spp. Neurotoxic
Capsicum frutescens L. spp. Radioprotective
Capsicum frutescens L. spp. Rubefacient
Capsicum frutescens L. spp. Sialagogue
Capsicum frutescens L. spp. Stimulant
Capsicum frutescens L. spp. Stomachic
Capsicum frutescens L. spp. Synergist
Capsicum frutescens L. spp. Thermogenic
Capsicum frutescens L. spp. Tonic
Capsicum frutescens L. spp. Ulcerogenic
Capsicum frutescens L. spp. Uterocontractant
Capsicum frutescens L. spp. Vasoconstrictor
Capsicum frutescens L. spp. Vulnerary
Capsicum frutescens L. spp. Water Retention

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00048640 External link 512 CAY-1
CHEMBL1988088
No. 21 No. 11
C00003108 External link 512 Capsidiol
C081843
No. 1914 No. 38
C00001425 External link 512 Octopamine
CHEMBL53929
CHEMBL1160703
D009655
16 / 8 / 6 7 / 0 No. 4586

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001425 1 / 0
Q99700 Ataxin-2 Unclassified protein C00001425 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001425 2 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001425 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001425 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001425 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001425 0 / 0
P46098 5-hydroxytryptamine receptor 3A NS C00001425 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001425 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00001425 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001425 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001425 0 / 1
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001425 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001425 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001425 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001425 0 / 0

7 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00001425
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00001425
155 ADRB3, BETA3AR adrenoceptor beta 3 C00001425
6530 SLC6A2, NAT1, NET, NET1, SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 2 C00001425
6531 SLC6A3, DAT, DAT1, PKDYS solute carrier family 6 (neurotransmitter transporter), member 3 C00001425
6532 SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT solute carrier family 6 (neurotransmitter transporter), member 4 C00001425
134864 TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 trace amine associated receptor 1 C00001425

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)