Species

KNApSAcK Entry

Organism name Aconitum japonicum
Genus Aconitum
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aconitum
Linked NCBI taxonomy ID 49188
Linked level genus

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025018 External link 512 Subdesculine
/ Anhydroepoxynapelline 12-acetate
No. 124 No. 10
C00001644 External link 512 Hypaconitine
CHEMBL400315
CHEMBL2062951
C058309
7 / 0 No. 138 No. 10
C00039377 External link 512 Hokbusine A
CHEMBL439232
No. 138 No. 10
C00038990 External link 512 Deoxyjesaconitine
CHEMBL247593
No. 138 No. 10
C00038407 External link 512 Aljesaconitine A
CHEMBL249661
No. 138 No. 10
C00028166 External link 512 Deoxyaconitine
/ 3-Deoxyaconitine
CHEMBL400316
CHEMBL2062827
C057219
No. 138 No. 10
C00001846 External link 512 (+)-Demethylcoclaurine
CHEMBL19344
CHEMBL501778
CHEMBL470491
2 / 2 / 0 No. 253 No. 4
C00024915 External link 512 Isohypognavine
/ Isohypognavinol 2-benzoate
No. 317
C00024912 External link 512 Ignavine
C035745
No. 317

Human Protein / Gene in interactions

2 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P14416 D(2) dopamine receptor Dopamine receptor C00001846 2 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00001846 0 / 0

7 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001644
1557 CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00001644
1558 CYP2C8, CPC8, CYPIIC8, MP-12/MP-20 cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1) C00001644
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) C00001644
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00001644
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00001644
1577 CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) C00001644

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#159900 Myoclonic dystonia P14416