Species

KNApSAcK Entry

Organism name Guarea macrophylla ssp.tuberculata
Genus Guarea
Family Meliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Guarea
Linked NCBI taxonomy ID 43908
Linked level genus

Family

Family in NCBI taxonomy Meliaceae
ID 43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (24)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00034873 External link 512 Manoyl oxide
/ (+)-Manoyl oxide
CHEMBL432233
CHEMBL496057
No. 70
C00003161 External link 512 Ledol
/ (+)-Ledol
CHEMBL2171207
1 / 2 / 3 No. 197 No. 38
C00021212 External link 512 Palustrol
No. 197 No. 38
C00020154 External link 512 T-Muurolol
/ epi-alpha-Muurolol
CHEMBL486795
No. 205 No. 38
C00029421 External link 512 epi-Cubenol
/ 1-epi-Cubenol
/ (+)-ent-Epicubenol
No. 205 No. 38
C00034905 External link 512 tau-Cadinol
CHEMBL486795
C072576
No. 205 No. 38
C00034854 External link 512 Guai-6-en-10beta-ol
No. 205 No. 38
C00034866 External link 512 Isopimara-7,15-diene
No. 208 No. 48
C00034863 External link 512 Isopimara-7,15-dien-2alpha-ol
/ (+)-Isopimara-7,15-dien-2alpha-ol
No. 208 No. 48
C00034864 External link 512 Isopimara-7,15-dien-3beta-ol
/ (-)-Isopimara-7,15-dien-3beta-ol
CHEMBL225866
No. 208 No. 48
C00020051 External link 512 alpha-Cadinene
No. 283 No. 39
C00030345 External link 512 gamma-Cadinene
C054278
No. 283 No. 39
C00003203 External link 512 alpha-Ylangene
No. 333 No. 38
C00003120 External link 512 alpha-Cubebene
No. 333 No. 38
C00003118 External link 512 Copaene
/ alpha-Copaene
/ (-)-alpha-Copaene
No. 333 No. 38
C00003110 External link 512 Caryophyllene
/ (E)-Caryophyllene
/ beta-Caryophyllene
/ (-)-(E)-Caryophyllene
/ (E)-beta-Caryophyllene
CHEMBL445740
CHEMBL448700
2 / 3 / 7 No. 478 No. 38
C00021227 External link 512 alpha-Gurjunene
No. 595 No. 38
C00021229 External link 512 Alloaromadendrene
/ allo-Aromadendrene
CHEMBL509805
CHEMBL596664
No. 640
C00012425 External link 512 Bicyclogermacren
/ Bicyclogermacrene
/ (+)-Bicyclogermacrene
CHEMBL509566
No. 699 No. 38
C00029674 External link 512 alpha-Terpineol
CHEMBL447597
CHEMBL449810
C016775
3 / 16 / 11 No. 983 No. 35
C00034865 External link 512 Isopimara-7,15-dien-3-one
CHEMBL1097037
No. 1309 No. 48
C00003147 External link 512 Humulene
/ alpha-Caryophyllene
/ (+/-)-alpha-Humulene
CHEMBL251280
C042686
No. 1421 No. 38
C00000149 External link 512 Spathulenol
CHEMBL518542
CHEMBL1774433
C013258
No. 1603
C00011720 External link 512 Germacrene D
/ (-)-Germacrene D
CHEMBL105432
CHEMBL1836650
No. 2639 No. 38

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00029674 3 / 0
P02545 Prelamin-A/C Unclassified protein C00029674 11 / 10
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00003161 2 / 3
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00029674 5 / 1
O00255 Menin Unclassified protein C00003110 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003110 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (21)

OMIM preferred title UniProt
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#143500 Gilbert syndrome P22309
P22310
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#114550 Hepatocellular carcinoma P08581
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#145000 Hyperparathyroidism 1; hrpt1 O00255
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (21)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00018 Gastric cancer P08581 (related)
H00021 Renal cell carcinoma P08581 (related)
H00046 Cholangiocarcinoma P08581 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)