Species

KNApSAcK Entry

Organism name Aconitum napellus L.ssp.vulgare
Genus Aconitum
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aconitum
Linked NCBI taxonomy ID 49188
Linked level genus

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00029224 External link 512 Virescenine
No. 31 No. 10
C00028990 External link 512 Senbusine A
No. 31 No. 10
C00027666 External link 512 12-epi-Dehydronapelline
/ (+)-12-Epidehydronapelline
No. 124 No. 10
C00024959 External link 512 Songoramine
/ Zongoramine
No. 124 No. 10
C00024807 External link 512 12-Epinapelline
/ 12-Epiluciculine
/ 12-epi-Napelline
CHEMBL1487558
CHEMBL1741394
9 / 3 / 5 No. 124 No. 10
C00001663 External link 512 Songorin
/ Napellonin
/ Napellonine
/ Bullatine G
CHEMBL1895895
CHEMBL2165580
C057217
1 / 0 / 0 No. 124 No. 10

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00024807 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00024807 0 / 1
P11308 Transcriptional regulator ERG Unclassified protein C00024807 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00024807 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00024807 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00024807 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00024807 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00024807 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001663 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00024807 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#612219 Ewing sarcoma; es P11308

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)