PCIDB

Piper lhotzkyanum

Family in NCBI taxonomy	Piperaceae
ID	16739

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	Magnoliophyta
ID	3398

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster
C00014013	Kaplanin / 8-beta-D-Glucopyranosyl-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one					No. 22	No. 15
C00000999	Sakuranetin / Naringenin 7-O-methyl ether / 5,4'-Dihydroxy-7-methoxyflavanone	CHEMBL74852 CHEMBL448297	C099724	19 / 20 / 20		No. 25	No. 14
C00000163	alpha-Eudesmol		C118684			No. 524	No. 38
C00000164	beta-Eudesmol	CHEMBL88244	C051082			No. 524	No. 38
C00033916	Hinesol / (-)-Hinesol	CHEMBL505813	C065858			No. 613	No. 38
C00042493	epi-gamma-Eudesmol / (-)-epi-gamma-Eudesmol	CHEMBL477900				No. 613	No. 38
C00003467	Phytol / trans-Phytol	CHEMBL390773 CHEMBL1644111	D010836		0 / 5	No. 641	No. 38
C00036458	2,4,5-Trimethoxystyrene	CHEMBL488200	C056257			No. 723	No. 6
C00000149	Spathulenol	CHEMBL518542 CHEMBL1774433	C013258			No. 1603
C00003139	Guaiol	CHEMBL226915				No. 1669	No. 38
C00002714	Apiol / Apiole / Parsley apiole	CHEMBL1560118		3 / 0 / 1		No. 1917	No. 6
C00042696	Lhotzchromene					No. 2800

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	C00000999	1 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00000999	0 / 0
P04062	Glucosylceramidase	Enzyme	C00000999	6 / 4
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000999	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00000999	1 / 4
P11473	Vitamin D3 receptor	NR1I1	C00000999	2 / 3
Q9Y3R4	Sialidase-2	Enzyme	C00000999	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000999	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000999	2 / 0
O75496	Geminin	Unclassified protein	C00000999	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000999	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00000999	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002714	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000999	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002714	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002714	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00000999	4 / 3
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000999	1 / 1
P59538	Taste receptor type 2 member 31	Taste receptor (taste family GPCR)	C00000999	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000999	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000999	1 / 4
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000999	1 / 1

OMIM	preferred title	UniProt
#612069	Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10	Q13148
#208900	Ataxia-telangiectasia; at	Q13315
#114500	Colorectal cancer; crc	P84022
#600274	Frontotemporal dementia; ftd	P10636
#608013	Gaucher disease, perinatal lethal	P04062
#230800	Gaucher disease, type i	P04062
#230900	Gaucher disease, type ii	P04062
#231000	Gaucher disease, type iii	P04062
#231005	Gaucher disease, type iiic	P04062
#613795	Loeys-dietz syndrome, type 3; lds3	P84022
#607948	Mycobacterium tuberculosis, susceptibility to	P11473
#168600	Parkinson disease, late-onset; pd	P04062
#260540	Parkinson-dementia syndrome	P10636
#172700	Pick disease of brain	P10636
#601399	Platelet disorder, familial, with associated myeloid malignancy	Q01196
#183090	Spinocerebellar ataxia 2; sca2	Q99700
#607250	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1	Q9NUW8
#601104	Supranuclear palsy, progressive, 1; psnp1	P10636
#277440	Vitamin d-dependent rickets, type 2a; vddr2a	P11473
#278750	Xeroderma pigmentosum, variant type; xpv	Q9Y253

KEGG	name	UniProt
H00066	Lewy body dementia (LBD)	P04062 (related)
H00126	Gaucher disease	P04062 (related)
H00426	Defects in the degradation of ganglioside	P04062 (related)
H00810	Progressive myoclonic epilepsy (PME)	P04062 (related)
H00036	Osteosarcoma	P08684 (marker)
H00058	Amyotrophic lateral sclerosis (ALS)	P10636 (related) Q13148 (related)
H00077	Progressive supranuclear palsy (PSP)	P10636 (related)
H00078	Frontotemporal lobar degeneration (FTLD)	P10636 (related)
H00342	Tuberculosis	P11473 (related)
H00784	Localized autosomal recessive hypotrichosis	P11473 (related)
H01143	Vitamin D-dependent rickets	P11473 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q01196 (related) Q01196 (marker)
H00003	Acute myeloid leukemia (AML)	Q01196 (related) Q01196 (marker) Q13951 (marker)
H00004	Chronic myeloid leukemia (CML)	Q01196 (related)
H00978	Thrombocytopenia (THC)	Q01196 (related)
H00005	Chronic lymphocytic leukemia (CLL)	Q13315 (related)
H00064	Ataxia telangiectasia (AT)	Q13315 (related)
H00094	DNA repair defects	Q13315 (related)
H00848	Ataxia with ocular apraxia (AOA)	Q13315 (related)
H00063	Spinocerebellar ataxia (SCA)	Q99700 (related) Q9NUW8 (related)
H00403	Disorders of nucleotide excision repair	Q9Y253 (related)