Aspidosperma marcgravianum
Species
KNApSAcK Entry
| Organism name | Aspidosperma marcgravianum |
|---|---|
| Genus | Aspidosperma |
| Family | Apocynaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Aspidosperma marcgravianum |
|---|---|
| Linked NCBI taxonomy ID | 597276 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apocynaceae |
|---|---|
| ID | 4056 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (10)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001690
|
Aricine
|
CHEMBL525626
|
C017997
|
No. 246 | No. 4 |
|
||
|
C00024569
|
Limapodine
/ (+)-Limapodine / N-Acetyl-N-depropionyllimaspermine |
No. 430 | No. 4 |
|
||||
|
C00024515
|
Aspidocarpine
|
CHEMBL1173074
CHEMBL1317059 CHEMBL1338579 |
5 / 5 / 9 | No. 430 | No. 4 |
|
||
|
C00026861
|
Dihydrocorynantheol
|
C007398
|
No. 1226 |
|
||||
|
C00024518
|
Aspidolimidin
/ Aspidolimidine |
No. 1354 | No. 4 |
|
||||
|
C00024492
|
18-Oxohaplocidine
|
No. 1354 | No. 4 |
|
||||
|
C00024536
|
Haplocidine
|
No. 1354 | No. 4 |
|
||||
|
C00002173
|
Hydroquinidine
|
CHEMBL531471
CHEMBL531472 CHEMBL588934 CHEMBL602767 CHEMBL1436416 CHEMBL1531111 CHEMBL1617471 CHEMBL1740727 CHEMBL1906890 CHEMBL2079611 CHEMBL2092739 CHEMBL2305514 CHEMBL2355802 |
C014486
|
9 / 12 / 15 | 0 / 4 | No. 1378 | No. 7 |
|
|
C00024595
|
Rhazinilam
/ (-)-Rhazinilam |
CHEMBL302501
|
C009170
|
No. 3045 |
|
|||
|
C00024606
|
Tetrahydrosecodine
|
No. 4988 |
|
Human Protein / Gene in interactions
10 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002173 C00024515 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00002173 C00024515 | 2 / 5 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002173 C00024515 | 0 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002173 C00024515 | 1 / 2 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002173 | 2 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002173 | 3 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002173 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002173 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00002173 | 3 / 2 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00024515 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (13)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (16)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|