Species

KNApSAcK Entry

Organism name Pogonopus speciosus
Genus Pogonopus
Family Rubiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Pogonopus speciosus
Linked NCBI taxonomy ID 43555
Linked level species

Family

Family in NCBI taxonomy Rubiaceae
ID 24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001778 External link 512 Tubulosine
/ (-)-Tubulosine
CHEMBL518568
CHEMBL535307
CHEMBL1254284
CHEMBL1369261
C009805
19 / 18 / 10 No. 510 No. 4
C00001907 External link 512 Psychotrine
CHEMBL463445
No. 510 No. 4
C00049409 External link 512 1',2',3',4'-Tetradehydrotubulosine
CHEMBL481241
No. 5199 No. 4

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001778 1 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001778 4 / 1
Q99700 Ataxin-2 Unclassified protein C00001778 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001778 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001778 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001778 2 / 0
O75496 Geminin Unclassified protein C00001778 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001778 7 / 3
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase C00001778 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001778 0 / 0
P23467 Receptor-type tyrosine-protein phosphatase beta Receptor tyrosine-protein phosphatase C00001778 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001778 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001778 0 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00001778 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001778 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001778 1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001778 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00001778 0 / 0
Q06710 Paired box protein Pax-8 Unclassified protein C00001778 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (10)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00032 Thyroid cancer Q06710 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) Q06710 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)