| Organism name | Buxus sempervirens |
|---|---|
| Genus | Buxus |
| Family | Buxaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Buxus sempervirens |
|---|---|
| Linked NCBI taxonomy ID | 4002 |
| Linked level | species |
| Family in NCBI taxonomy | Buxaceae |
|---|---|
| ID | 4000 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00005681
|
Galactobuxin
|
No. 2 | No. 15 |
|
||||
|
C00004712
|
Artemetin
/ 3,6,7,3',4'-Pentamethylquercetagetin / Quercetagetin 3,6,7,3',4'-pentamethyl ether / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one |
CHEMBL225700
|
C054132
|
0 / 5 | No. 8 | No. 15 |
|
|
|
C00001816
|
(+)-Bebeerine
|
CHEMBL1169627
|
C066405
|
13 / 6 / 5 | No. 10 | No. 4 |
|
|
|
C00025479
|
Buxaminol B
|
No. 292 | No. 11 |
|
||||
|
C00002241
|
Buxamine E
|
No. 292 | No. 11 |
|
||||
|
C00049055
|
(+)-Buxamine F
|
CHEMBL491333
|
No. 292 | No. 11 |
|
|||
|
C00025532
|
Sempervirone
|
No. 845 |
|
|||||
|
C00025487
|
Cyclobuxophylline O
|
No. 845 |
|
|||||
|
C00027648
|
(Z)-Cyclobuxaphylamine
/ (-)-(Z)-Cyclobuxaphylamine |
No. 845 |
|
|||||
|
C00025483
|
Buxithienine M
|
No. 845 |
|
|||||
|
C00049054
|
(+)-17-Oxocycloprotobuxine
|
CHEMBL492177
|
No. 845 |
|
||||
|
C00002252
|
Irehine
|
No. 916 | No. 11 |
|
||||
|
C00002247
|
Cyclovirobuxine C
|
No. 917 | No. 11 |
|
||||
|
C00002246
|
Cycloprotobuxine C
|
CHEMBL1976863
|
No. 917 | No. 11 |
|
|||
|
C00025485
|
Buxozine C
|
No. 917 | No. 11 |
|
||||
|
C00025522
|
N-Benzoylbuxodienine E
|
No. 1058 |
|
|||||
|
C00002244
|
Cyclobuxine D
|
C083065
|
No. 1260 | No. 11 |
|
|||
|
C00025486
|
Cyclobuxargentine G
|
No. 1260 | No. 11 |
|
||||
|
C00025531
|
Semperviramidine
/ (+)-Semperviramidine |
No. 1367 |
|
|||||
|
C00028644
|
Na-Demethylsemperviraminone
/ (+)-Na-Demethylsemperviraminone |
No. 4653 |
|
|||||
|
C00025523
|
N-Benzoylcyclovirobuxenine E
|
No. 7441 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001816 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001816 | 1 / 1 |
| P47898 | 5-hydroxytryptamine receptor 5A | Serotonin receptor | C00001816 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00001816 | 1 / 1 |
| O75496 | Geminin | Unclassified protein | C00001816 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00001816 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001816 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001816 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001816 | 4 / 3 |
| O43603 | Galanin receptor type 2 | Galanin receptor | C00001816 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001816 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001816 | 0 / 0 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00001816 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143100 | Huntington disease; hd |
P42858
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|