Menispermum dauricum
Species
KNApSAcK Entry
| Organism name | Menispermum dauricum |
|---|---|
| Genus | Menispermum |
| Family | Menispermaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Menispermum dauricum |
|---|---|
| Linked NCBI taxonomy ID | 49683 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Menispermaceae |
|---|---|
| ID | 3455 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (13)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001817
|
Berbamine
/ d-Berbamine / (+)-Berbamine |
CHEMBL504323
CHEMBL507540 CHEMBL1198334 |
C027870
|
4 / 3 / 4 | 9 / 1 | No. 10 | No. 4 |
|
|
C00027338
|
Daurioxoisoporphine C
|
CHEMBL1651051
|
No. 74 |
|
||||
|
C00027337
|
Daurioxoisoporphine B
|
CHEMBL446816
|
No. 74 |
|
||||
|
C00027339
|
Daurioxoisoporphine D
|
No. 74 |
|
|||||
|
C00028131
|
Dauricine
|
CHEMBL442717
CHEMBL1721004 CHEMBL1995008 |
C035934
|
2 / 2 / 2 | 1 / 2 | No. 89 | No. 4 |
|
|
C00001845
|
Dauricine
|
CHEMBL442717
CHEMBL1721004 CHEMBL1995008 |
C035934
|
2 / 2 / 2 | 1 / 2 | No. 89 | No. 4 |
|
|
C00002310
|
Acutumidine
|
CHEMBL237548
CHEMBL237765 |
No. 915 |
|
||||
|
C00027340
|
Dechloroacutumine
|
CHEMBL237764
|
No. 915 |
|
||||
|
C00027334
|
Dauricumidine
|
CHEMBL237548
CHEMBL237765 |
No. 915 |
|
||||
|
C00027335
|
Dauricumine
|
CHEMBL391628
CHEMBL391835 CHEMBL1716763 |
1 / 0 / 0 | No. 915 |
|
|||
|
C00035573
|
Dechlorodauricumine
/ (+)-Dechlorodauricumine |
CHEMBL237764
|
No. 915 |
|
||||
|
C00003486
|
Strigol
/ (+)-Strigol |
No. 1816 | No. 38 |
|
||||
|
C00027336
|
Daurioxoisoporphine A
|
CHEMBL523250
|
No. 8327 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001845 C00027335 C00028131 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001845 C00028131 | 2 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001817 | 3 / 3 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001817 | 0 / 0 |
| P54750 | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | PDE_1A | C00001817 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001817 | 0 / 1 |
10 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00001845
C00028131
|
| 1147 | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) |
C00001817
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00001817
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001817
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00001817
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00001817
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00001817
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001817
|
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) |
C00001817
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00001817
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (5)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
KEGG DISEASE (6)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|