Fumaria parviflora
Species
KNApSAcK Entry
| Organism name | Fumaria parviflora |
|---|---|
| Genus | Fumaria |
| Family | Fumariaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Fumaria |
|---|---|
| Linked NCBI taxonomy ID | 200992 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (16)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00027327
|
Corledine
|
|
||||||
|
C00005427
|
Quercetin 3,7-diglucoside
/ Quercetin 3,7-O-beta-diglucopyranoside / Quercetin 3,7-di-O-beta-D-glucopyranoside |
CHEMBL1797051
|
No. 1 | No. 15 |
|
|||
|
C00005169
|
Nicotiflorin
/ Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside |
CHEMBL431610
CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691 |
22 / 10 / 12 | No. 1 | No. 15 |
|
||
|
C00005166
|
Kaempferol 3-gentiobioside
/ Kaempferol 3-O-gentiobioside |
No. 1 | No. 15 |
|
||||
|
C00005181
|
Kaempferol 3-glucoside-7-galactoside
|
CHEMBL2206209
|
No. 1 | No. 15 |
|
|||
|
C00026095
|
Stylopine
/ (-)-Stylopine / l-Tetrahydrocoptisine / (-)-Tetrahydrocoptisine |
CHEMBL1922602
|
No. 37 | No. 4 |
|
|||
|
C00026144
|
Sinactine
/ Tetrahydroepiberberine |
No. 37 | No. 4 |
|
||||
|
C00024668
|
YHL II
/ Coptisine |
CHEMBL362071
|
C034384
|
No. 155 | No. 4 |
|
||
|
C00001847
|
Dihydrosanguinarine
|
CHEMBL465678
|
No. 195 | No. 4 |
|
|||
|
C00001900
|
Parfumine
/ d-Parfumine / (+)-Parfumine |
CHEMBL1968957
|
No. 512 | No. 4 |
|
|||
|
C00027368
|
Fumariline
|
C049095
|
No. 512 | No. 4 |
|
|||
|
C00027452
|
O-Acetylfumaricine
/ Fumaricine acetate / O-Methylfumarophycine / (-)-O-Methylfumarophycine |
No. 512 | No. 4 |
|
||||
|
C00001867
|
alpha-Hydrastine
/ (-)-alpha-Hydrastine |
CHEMBL475536
CHEMBL462731 CHEMBL1256868 CHEMBL1256919 CHEMBL1408680 CHEMBL1412842 CHEMBL1441048 |
21 / 35 / 30 | No. 605 | No. 4 |
|
||
|
C00027328
|
Corlumidine
/ (+)-Corlumidine |
No. 605 | No. 4 |
|
||||
|
C00027268
|
Adlumiceine
|
No. 2202 | No. 4 |
|
||||
|
C00027269
|
Adlumidiceine
|
No. 2202 | No. 4 |
|
Human Protein / Gene in interactions
40 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00001867 C00005169 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001867 C00005169 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001867 C00005169 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005169 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00005169 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00001867 | 6 / 4 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00005169 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005169 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001867 | 11 / 10 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001867 | 3 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00005169 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001867 | 0 / 1 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005169 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00001867 | 1 / 2 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005169 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00005169 | 2 / 3 |
| P39748 | Flap endonuclease 1 | Enzyme | C00005169 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001867 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001867 | 1 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00005169 | 1 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001867 | 2 / 2 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00001867 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001867 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001867 | 3 / 3 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001867 | 5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001867 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001867 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001867 | 0 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00005169 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00005169 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00005169 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00005169 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001867 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00005169 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00001867 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001867 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00005169 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00005169 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005169 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00005169 | 2 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (44)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (40)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|