Species

KNApSAcK Entry

Organism name Dehaasia incrassata
Genus Dehaasia
Family Lauraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Dehaasia incrassata
Linked NCBI taxonomy ID 128613
Linked level species

Family

Family in NCBI taxonomy Lauraceae
ID 3433

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001897 External link 512 Oxyacanthine
CHEMBL510022
CHEMBL509999
CHEMBL1983122
C092646
5 / 4 / 1 No. 10 No. 4
C00001872 External link 512 Isocorydine
/ (+)-Isocorydine
/ L-(+)-Isocorydine
/ (S)-(+)-Isocorydine
CHEMBL489525
CHEMBL1376826
14 / 7 / 10 No. 20 No. 4
C00027438 External link 512 Sanjoinine Ib
/ Norisocorydine
CHEMBL465212
No. 20 No. 4

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001872 C00001897 1 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001872 1 / 1
P24941 Cyclin-dependent kinase 2 Cdc2 C00001872 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001872 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00001872 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001897 2 / 0
O75496 Geminin Unclassified protein C00001872 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001872 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001872 3 / 3
Q99700 Ataxin-2 Unclassified protein C00001897 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001872 0 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00001897 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001872 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001872 1 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001872 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001872 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001872 0 / 0
P43351 DNA repair protein RAD52 homolog Unclassified protein C00001897 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (11)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)