Species

KNApSAcK Entry

Organism name Thalictrum delavayi
Genus Thalictrum
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Thalictrum delavayi
Linked NCBI taxonomy ID 1084667
Linked level species

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001872 External link 512 Isocorydine
/ (+)-Isocorydine
/ L-(+)-Isocorydine
/ (S)-(+)-Isocorydine
CHEMBL489525
CHEMBL1376826
14 / 7 / 10 No. 20 No. 4
C00027447 External link 512 Ocotein
/ Ocoteine
/ Thalicmin
/ Thalicmine
CHEMBL443099
No. 20 No. 4
C00001885 External link 512 Escholin
/ Escholine
/ Thalictrin
/ Thalictrine
/ Magnoflorine
/ (+)-Magnoflorine
CHEMBL235428
C001670
No. 286 No. 4
C00029099 External link 512 Thalicthuberine
CHEMBL518852
No. 639
C00027558 External link 512 Leucoxylonine
No. 3042
C00027375 External link 512 Hernandaline
/ (+)-Hernandaline
No. 3311

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001872 1 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00001872 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001872 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00001872 0 / 0
O75496 Geminin Unclassified protein C00001872 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001872 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001872 3 / 3
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001872 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001872 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001872 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001872 1 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001872 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001872 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001872 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196

KEGG DISEASE (10)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)