Species

KNApSAcK Entry

Organism name Thalictrum flavum L.
Genus Thalictrum
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Thalictrum flavum
Linked NCBI taxonomy ID 150094
Linked level species

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001885 External link 512 Escholin
/ Escholine
/ Thalictrin
/ Thalictrine
/ Magnoflorine
/ (+)-Magnoflorine
CHEMBL235428
C001670
No. 286 No. 4
C00027332 External link 512 Cryptopin
/ Cryptopine
/ Kryptopine
/ Kryptocavin
/ Cryptocavine
CHEMBL1339015
C007159
6 / 5 / 8 No. 820 No. 4
C00026062 External link 512 Thalflavine
No. 3603

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00027332 1 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00027332 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00027332 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00027332 0 / 0
O00255 Menin Unclassified protein C00027332 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00027332 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (8)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)