PCIDB

KNApSAcK Metabolite C00027332

Metabolite

KNApSAcK Entry

id C00027332
Name Cryptopin / Cryptopine / Kryptopine / Kryptocavin / Cryptocavine
CAS RN 482-74-6
Standard InChI InChI=1S/C21H23NO5/c1-22-7-6-14-9-19(24-2)20(25-3)10-15(14)17(23)8-13-4-5-18-21(16(13)11-22)27-12-26-18/h4-5,9-10H,6-8,11-12H2,1-3H3
Standard InChI (Main Layer) InChI=1S/C21H23NO5/c1-22-7-6-14-9-19(24-2)20(25-3)10-15(14)17(23)8-13-4-5-18-21(16(13)11-22)27-12-26-18/h4-5,9-10H,6-8,11-12H2,1-3H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 820

Link

ChEMBL

By standard InChI CHEMBL1339015
By standard InChI Main Layer CHEMBL1339015

KEGG

By LinkDB

CTD

By CAS RN C007159

Species

Summary

Plant class

class name count
eudicotyledons 24

Family

family name count
Papaveraceae 22
Ranunculaceae 2

List (24)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Corydalis esquirolii 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis gortschakovii 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis nobilis 38909 Papaveraceae eudicotyledons Viridiplantae
Corydalis omeiensis 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis sewerzovii 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis stewartii 3463 Papaveraceae eudicotyledons Viridiplantae
Dicentra chrysantha 54420 Papaveraceae eudicotyledons Viridiplantae
Fumaria agraria 1095357 Papaveraceae eudicotyledons Viridiplantae
Fumaria capreolata 1053349 Papaveraceae eudicotyledons Viridiplantae
Fumaria densiflora 1092452 Papaveraceae eudicotyledons Viridiplantae
Fumaria officinalis L. 200993 Papaveraceae eudicotyledons Viridiplantae
Fumaria parviflora Lam. 200992 Papaveraceae eudicotyledons Viridiplantae
Fumaria vaillantii 367484 Papaveraceae eudicotyledons Viridiplantae
Hypecoum procumbens 391933 Papaveraceae eudicotyledons Viridiplantae
Meconopsis robusta 72195 Papaveraceae eudicotyledons Viridiplantae
Papaver californicum 74822 Papaveraceae eudicotyledons Viridiplantae
Papaver confine 3468 Papaveraceae eudicotyledons Viridiplantae
Papaver radicatum 357475 Papaveraceae eudicotyledons Viridiplantae
Papaver rhoeas chelidonides 3468 Papaveraceae eudicotyledons Viridiplantae
Papaver rhopalothece 3468 Papaveraceae eudicotyledons Viridiplantae
Papaver somniferum 3469 Papaveraceae eudicotyledons Viridiplantae
Stylophorum lasiocarpum 72189 Papaveraceae eudicotyledons Viridiplantae
Thalictrum flavum L. 150094 Ranunculaceae eudicotyledons Viridiplantae
Thalictrum glandulosissimum 46968 Ranunculaceae eudicotyledons Viridiplantae

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1339015 CHEMBL1614110 (1)
1 / 0
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1339015 CHEMBL1794401 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1339015 CHEMBL1613777 (1)
1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL1339015 CHEMBL1613914 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL1339015 CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1339015 CHEMBL1614531 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (8)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)