Fumaria densiflora

• Index
• Plant Species
• Metabolite list (17)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Fumaria densiflora
Genus	Fumaria
Family	Fumariaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Fumaria densiflora
Linked NCBI taxonomy ID	1092452
Linked level	species

Family

Family in NCBI taxonomy	Papaveraceae
ID	3465

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (17)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00025655	Corytuberine / (+)-Corytuberine	CHEMBL227965	C013896	1 / 0 / 0		No. 20	No. 4
C00026092	Scoulerine / (-)-Scoulerine	CHEMBL191133 CHEMBL1235966 CHEMBL1395394		27 / 19 / 15		No. 37	No. 4
C00026095	Stylopine / (-)-Stylopine / l-Tetrahydrocoptisine / (-)-Tetrahydrocoptisine	CHEMBL1922602				No. 37	No. 4
C00026144	Sinactine / Tetrahydroepiberberine					No. 37	No. 4
C00027159	Depiline / Palmatine / Berbericinine / O,O-Dimethyldemethyleneberberine	CHEMBL206106	C005413	8 / 13 / 13	8 / 0	No. 155	No. 4
C00001859	Fumaricine					No. 512	No. 4
C00027539	Fumaritridine					No. 512	No. 4
C00001900	Parfumine / d-Parfumine / (+)-Parfumine	CHEMBL1968957				No. 512	No. 4
C00027368	Fumariline		C049095			No. 512	No. 4
C00027452	O-Acetylfumaricine / Fumaricine acetate / O-Methylfumarophycine / (-)-O-Methylfumarophycine					No. 512	No. 4
C00027369	Fumarophycine / O-Acetylfumaritine					No. 512	No. 4
C00027540	Fumarofine					No. 512	No. 4
C00001906	Fumarin / Biflorine / Protopine / Fumarine / Corydinine	CHEMBL453019	C009093	5 / 5 / 4	2 / 0	No. 820	No. 4
C00027332	Cryptopin / Cryptopine / Kryptopine / Kryptocavin / Cryptocavine	CHEMBL1339015	C007159	6 / 5 / 8		No. 820	No. 4
C00027268	Adlumiceine					No. 2202	No. 4
C00027269	Adlumidiceine					No. 2202	No. 4
C00027367	Fumaflorine					No. 3013

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001906 C00026092 C00027159 C00027332	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001906 C00026092 C00027159 C00027332	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001906 C00026092 C00027332	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001906 C00026092 C00027159	0 / 1
P02545	Prelamin-A/C	Unclassified protein	C00026092 C00027159	11 / 10
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00026092 C00027159	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00026092 C00027159	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00026092 C00027159	0 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00026092	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00027159	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00026092	0 / 0
O75496	Geminin	Unclassified protein	C00026092	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00026092	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00026092	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00026092	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00027332	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00026092	2 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00025655	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00001906	3 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00026092	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00026092	0 / 0
P29466	Caspase-1	C14	C00026092	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00026092	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00026092	0 / 0
O14727	Apoptotic protease-activating factor 1	Unclassified protein	C00026092	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00026092	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00026092	1 / 0
Q99700	Ataxin-2	Unclassified protein	C00026092	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00026092	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00026092	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00026092	0 / 0
O00255	Menin	Unclassified protein	C00027332	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00027332	1 / 2

10 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00027159
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00027159
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00027159
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00027159
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00027159
3570	IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80	interleukin 6 receptor	C00027159
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00027159
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00027159
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001906
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001906

Related Diseases

Diseases related to proteins in ChEMBL interactions