Fumaria officinalis L.
Species
KNApSAcK Entry
| Organism name | Fumaria officinalis L. |
|---|---|
| Genus | Fumaria |
| Family | Fumariaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Fumaria officinalis |
|---|---|
| Linked NCBI taxonomy ID | 200993 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Natural Activity
List (26)
| Species | Activity |
|---|---|
| Fumaria officinalis L. | Amphicholeretic |
| Fumaria officinalis L. | Anesthetic |
| Fumaria officinalis L. | Antiarrhythmic |
| Fumaria officinalis L. | Anticholinergic |
| Fumaria officinalis L. | Antihistaminic |
| Fumaria officinalis L. | Antiinflammatory |
| Fumaria officinalis L. | Antilithic |
| Fumaria officinalis L. | Antiseptic |
| Fumaria officinalis L. | Antispasmodic |
| Fumaria officinalis L. | Aphrodisiac |
| Fumaria officinalis L. | Bradycardic |
| Fumaria officinalis L. | Cholagogue |
| Fumaria officinalis L. | Cholekinetic |
| Fumaria officinalis L. | Choleretic |
| Fumaria officinalis L. | Depurative |
| Fumaria officinalis L. | Diaphoretic |
| Fumaria officinalis L. | Diuretic |
| Fumaria officinalis L. | Emetic |
| Fumaria officinalis L. | Hypertensive |
| Fumaria officinalis L. | Hypotensive |
| Fumaria officinalis L. | Laxative |
| Fumaria officinalis L. | Litholytic |
| Fumaria officinalis L. | Poison |
| Fumaria officinalis L. | Sedative |
| Fumaria officinalis L. | Stomachic |
| Fumaria officinalis L. | Tonic |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00026093
|
(-)-Sinactine
|
No. 37 | No. 4 |
|
||||
|
C00026139
|
N-Methylsinactine
|
No. 234 |
|
|||||
|
C00028283
|
Fumaritine
|
No. 512 | No. 4 |
|
||||
|
C00027332
|
Cryptopin
/ Cryptopine / Kryptopine / Kryptocavin / Cryptocavine |
CHEMBL1339015
|
C007159
|
6 / 5 / 8 | No. 820 | No. 4 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00027332 | 1 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00027332 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00027332 | 1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00027332 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00027332 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00027332 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (5)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|