Species

KNApSAcK Entry

Organism name Senecio miser
Genus Senecio
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Senecio
Linked NCBI taxonomy ID 18794
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002092 External link 512 Integerrimine
CHEMBL362153
CHEMBL488203
8 / 1 / 5 No. 622 No. 2
C00046027 External link 512 Integerrimine N-oxide
CHEMBL471683
No. 2356

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P39748 Flap endonuclease 1 Enzyme C00002092 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002092 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002092 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002092 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00002092 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00002092 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00002092 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002092 1 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)