PCIDB

KNApSAcK Metabolite C00002092

Metabolite

KNApSAcK Entry

id C00002092
Name Integerrimine
CAS RN 480-79-5
Standard InChI InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3/b12-4+/t11-,14-,15-,18-/m1/s1
Standard InChI (Main Layer) InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3

Cluster

Phytochemical cluster No. 2
KCF-S cluster No. 622

Link

ChEMBL

By standard InChI CHEMBL488203
By standard InChI Main Layer CHEMBL362153 CHEMBL488203

KEGG

By LinkDB C10328

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 22
asterids 13

Family

family name count
Fabaceae 22
Asteraceae 13

List (35)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Cacalia hastata 4210 Asteraceae asterids Viridiplantae
Crotalaria brevidens 1132170 Fabaceae rosids Viridiplantae
Crotalaria brevifolia 3828 Fabaceae rosids Viridiplantae
Crotalaria incana 46447 Fabaceae rosids Viridiplantae
Crotalaria intermedia 3828 Fabaceae rosids Viridiplantae
Crotalaria naragutensis 3828 Fabaceae rosids Viridiplantae
Crotalaria tetragona 1127393 Fabaceae rosids Viridiplantae
Crotalaria trichotoma 452830 Fabaceae rosids Viridiplantae
Lotononis alpina 379258 Fabaceae rosids Viridiplantae
Lotononis azurea 76394 Fabaceae rosids Viridiplantae
Lotononis brevicaulis 508262 Fabaceae rosids Viridiplantae
Lotononis caerulescens 76394 Fabaceae rosids Viridiplantae
Lotononis divaricata 508272 Fabaceae rosids Viridiplantae
Lotononis elongata 508273 Fabaceae rosids Viridiplantae
Lotononis hirsuta 508283 Fabaceae rosids Viridiplantae
Lotononis longicephala 76394 Fabaceae rosids Viridiplantae
Lotononis lotononoides 140935 Fabaceae rosids Viridiplantae
Lotononis meyeri 508294 Fabaceae rosids Viridiplantae
Lotononis pulchella 508304 Fabaceae rosids Viridiplantae
Lotononis purpurascens 76394 Fabaceae rosids Viridiplantae
Lotononis rigida 508308 Fabaceae rosids Viridiplantae
Lotononis sericophylla 508312 Fabaceae rosids Viridiplantae
Lotononis trichodes 76394 Fabaceae rosids Viridiplantae
Petasites hybridus 278673 Asteraceae asterids Viridiplantae
Pittocaulon filare 98711 Asteraceae asterids Viridiplantae
Pittocaulon praecox 98712 Asteraceae asterids Viridiplantae
Pittocaulon velatum 98711 Asteraceae asterids Viridiplantae
Senecio alpinus 189227 Asteraceae asterids Viridiplantae
Senecio brasiliensis 183623 Asteraceae asterids Viridiplantae
Senecio glabellum 18794 Asteraceae asterids Viridiplantae
Senecio integerrimus 344069 Asteraceae asterids Viridiplantae
Senecio longibolus 18794 Asteraceae asterids Viridiplantae
Senecio mairetianus 422354 Asteraceae asterids Viridiplantae
Senecio miser 18794 Asteraceae asterids Viridiplantae
Senecio squalidus 121554 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P39748 Flap endonuclease 1 Enzyme CHEMBL362153 CHEMBL1794486 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL362153 CHEMBL836230 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL362153 CHEMBL1794483 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL362153 CHEMBL1614211 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL362153 CHEMBL1794536 (1)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL362153 CHEMBL1613829 (1)
0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL362153 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL362153 CHEMBL1613933 (1)
1 / 6

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196

KEGG DISEASE (5)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)