Senecio mairetianus
Species
KNApSAcK Entry
| Organism name | Senecio mairetianus |
|---|---|
| Genus | Senecio |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Senecio mairetianus |
|---|---|
| Linked NCBI taxonomy ID | 422354 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (10)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002092
|
Integerrimine
|
CHEMBL362153
CHEMBL488203 |
8 / 1 / 5 | No. 622 | No. 2 |
|
||
|
C00002116
|
Senecionine
|
CHEMBL362153
CHEMBL488203 |
C009237
|
8 / 1 / 5 | 1 / 1 | No. 622 | No. 2 |
|
|
C00041644
|
Mairetolide C
/ (-)-Mairetolide C |
No. 685 |
|
|||||
|
C00041642
|
Mairetolide A
/ (-)-Mairetolide A |
No. 685 |
|
|||||
|
C00041643
|
Mairetolide B
/ (-)-Mairetolide B |
CHEMBL470124
|
No. 685 |
|
||||
|
C00041648
|
Mairetolide H
/ (-)-Mairetolide H |
No. 685 |
|
|||||
|
C00041647
|
Mairetolide F
/ (-)-Mairetolide F |
CHEMBL1099251
|
No. 685 |
|
||||
|
C00041646
|
Mairetolide E
/ (-)-Mairetolide E |
No. 685 |
|
|||||
|
C00041645
|
Mairetolide D
/ (-)-Mairetolide D |
No. 685 |
|
|||||
|
C00041641
|
Mairetin
/ (-)-Mairetin |
No. 4184 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P39748 | Flap endonuclease 1 | Enzyme | C00002092 C00002116 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002092 C00002116 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002092 C00002116 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002092 C00002116 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002092 C00002116 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002092 C00002116 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002092 C00002116 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002092 C00002116 | 1 / 4 |
1 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 54657 | UGT1A4, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D | UDP glucuronosyltransferase 1 family, polypeptide A4 (EC:2.4.1.17) |
C00002116
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (1)
| OMIM | preferred title | UniProt |
|---|---|---|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
KEGG DISEASE (5)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|